1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	A	A	A	E	E	L	D	V	D	G	I	A	V	R	L	T	S	P	D	R	M	Y	F	P	K	L	G	S	H	G	T	K	R	R	L	V	E	Y	Y	F	A	V	A	G	G	P	M	L	T	A	L	R	D	R	P	T	H	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?				?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	R	F	P	D	G	V	D	G	E	Q	I	Y	Q	K	R	I	P	R	H	R	P	D	Y	L	Q	T	C	R	V	T	F	P	S	G	R	M	A	D	A	L	K	V	T	H	P	A	A	I	V	W	A	A	Q	M	G	T	I	T	L
Secondary structure
SS confidence
Disorder																																	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		H	P	W	Q	V	R	C	P	D	T	E	H	P	D	E	L	R	I	D	L	D	P	Q	P	G	T	G	F	V	E	A	R	T	V	A	V	D	V	L	R	S	V	L	D	D	L	G	L	V	G	Y	P	K	T	S	G	G	R	G	I
Secondary structure
SS confidence
Disorder								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		H	V	F	L	R	I	A	T	D	W	D	F	V	E	V	R	R	A	G	I	A	L	A	R	E	V	E	R	R	A	P	D	A	V	T	T	S	W	W	K	E	E	R	G	A	R	I	F	I	D	F	N	Q	N	A	R	D	R	T	M
Secondary structure
SS confidence
Disorder																																						?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	S	A	Y	S	V	R	P	T	P	I	A	T	V	S	M	P	L	T	W	E	E	L	A	G	A	D	P	D	D	Y	T	M	T	T	V	P	E	L	V	K	I	R	D	D	P	W	A	G	M	D	D	V	A	Q	S	I	A	P	L
Secondary structure
SS confidence
Disorder																													?																								?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.
Sequence		L	D	L	A	A	A	D	E	E	R	G	L	G	D	M	P	Y	P	P	N	Y	P	K	M	P	G	E	P	K	R	V	Q	P	S	R	D	T	D	L	K	G	G	N	T	S	K
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 18%) Alpha helix ( 29%) Beta strand ( 23%)

Rank Aligned region

PDB 5op0 chain B Region: 5 - 335 Aligned: 330 Modelled: 331 Confidence: 100.0% Identity: 80% PDB header:transferase Chain: B: PDB Molecule:dna polymerase ligd, polymerase domain; PDBTitle: structure of prim-polc from mycobacterium smegmatis Phyre2 PDB 5dmu chain A Region: 2 - 300 Aligned: 294 Modelled: 299 Confidence: 100.0% Identity: 32% PDB header:transferase Chain: A: PDB Molecule:nhej polymerase; PDBTitle: structure of the nhej polymerase from methanocella paludicola Phyre2 PDB 2fao chain B Region: 7 - 302 Aligned: 289 Modelled: 296 Confidence: 100.0% Identity: 30% PDB header:hydrolase/transferase Chain: B: PDB Molecule:probable atp-dependent dna ligase; PDBTitle: crystal structure of pseudomonas aeruginosa ligd polymerase2 domain Phyre2 PDB 2iru chain A Region: 10 - 291 Aligned: 277 Modelled: 282 Confidence: 100.0% Identity: 27% PDB header:transferase Chain: A: PDB Molecule:putative dna ligase-like protein rv0938/mt0965; PDBTitle: crystal structure of the polymerase domain from mycobacterium2 tuberculosis ligase d Phyre2 PDB 1zt2 chain A domain 1 Region: 34 - 202 Aligned: 139 Modelled: 140 Confidence: 97.7% Identity: 20% Fold: Prim-pol domain Superfamily: Prim-pol domain Family: PriA-like Phyre2 PDB 4bpx chain C Region: 86 - 184 Aligned: 99 Modelled: 99 Confidence: 96.7% Identity: 14% PDB header:transferase Chain: C: PDB Molecule:dna primase small subunit; PDBTitle: crystal structure of human primase in complex with the primase-2 binding motif of dna polymerase alpha Phyre2 PDB 1v33 chain A Region: 135 - 184 Aligned: 49 Modelled: 49 Confidence: 96.6% Identity: 31% Fold: Prim-pol domain Superfamily: Prim-pol domain Family: PriA-like Phyre2 PDB 1g71 chain A Region: 135 - 184 Aligned: 49 Modelled: 49 Confidence: 96.3% Identity: 35% Fold: Prim-pol domain Superfamily: Prim-pol domain Family: PriA-like Phyre2 PDB 4lim chain A Region: 135 - 202 Aligned: 68 Modelled: 68 Confidence: 96.2% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:dna primase small subunit; PDBTitle: crystal structure of the catalytic subunit of yeast primase Phyre2 PDB 6a9w chain A Region: 134 - 184 Aligned: 45 Modelled: 51 Confidence: 81.6% Identity: 29% PDB header:replication Chain: A: PDB Molecule:primase; PDBTitle: structure of the bifunctional dna primase-polymerase from phage nrs-1 Phyre2 PDB 1k1s chain A domain 2 Region: 40 - 180 Aligned: 135 Modelled: 141 Confidence: 79.7% Identity: 10% Fold: DNA/RNA polymerases Superfamily: DNA/RNA polymerases Family: Lesion bypass DNA polymerase (Y-family), catalytic domain Phyre2 PDB 5gl6 chain A Region: 157 - 219 Aligned: 63 Modelled: 63 Confidence: 74.9% Identity: 8% PDB header:ribosomal protein Chain: A: PDB Molecule:ribosome maturation factor rimp; PDBTitle: msmeg rimp Phyre2 PDB 1ro0 chain A Region: 134 - 184 Aligned: 43 Modelled: 51 Confidence: 72.4% Identity: 19% Fold: Prim-pol domain Superfamily: Prim-pol domain Family: Bifunctional DNA primase/polymerase N-terminal domain Phyre2 PDB 4bax chain H Region: 106 - 186 Aligned: 77 Modelled: 81 Confidence: 63.2% Identity: 17% PDB header:ligase Chain: H: PDB Molecule:glutamine synthetase; PDBTitle: crystal structure of glutamine synthetase from streptomyces2 coelicolor Phyre2 PDB 1jx4 chain A domain 2 Region: 40 - 178 Aligned: 132 Modelled: 139 Confidence: 61.7% Identity: 12% Fold: DNA/RNA polymerases Superfamily: DNA/RNA polymerases Family: Lesion bypass DNA polymerase (Y-family), catalytic domain Phyre2 PDB 2d3a chain J Region: 106 - 229 Aligned: 120 Modelled: 124 Confidence: 61.4% Identity: 23% PDB header:ligase Chain: J: PDB Molecule:glutamine synthetase; PDBTitle: crystal structure of the maize glutamine synthetase2 complexed with adp and methionine sulfoximine phosphate Phyre2 PDB 3ebk chain A Region: 212 - 246 Aligned: 33 Modelled: 35 Confidence: 57.8% Identity: 24% PDB header:allergen Chain: A: PDB Molecule:allergen bla g 4; PDBTitle: crystal structure of major allergens, bla g 4 from cockroaches Phyre2 PDB 4is4 chain G Region: 106 - 186 Aligned: 77 Modelled: 81 Confidence: 52.7% Identity: 21% PDB header:ligase Chain: G: PDB Molecule:glutamine synthetase; PDBTitle: the glutamine synthetase from the dicotyledonous plant m. truncatula2 is a decamer Phyre2 PDB 4kl0 chain A Region: 126 - 177 Aligned: 50 Modelled: 52 Confidence: 51.6% Identity: 18% PDB header:calcium binding protein Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of the effector protein xoo4466 Phyre2 PDB 5yrz chain D Region: 160 - 182 Aligned: 23 Modelled: 23 Confidence: 47.1% Identity: 35% PDB header:antitoxin/hydrolase Chain: D: PDB Molecule:hica; PDBTitle: toxin-antitoxin complex from streptococcus pneumoniae Phyre2 1 c5op0B_ 2 c5dmuA_ 3 c2faoB_ 4 c2iruA_ 5 d1zt2a1 6 c4bpxC_ 7 d1v33a_ 8 d1g71a_ 9 c4limA_ 10 c6a9wA_ 11 d1k1sa2 12 c5gl6A_ 13 d1ro0a_ 14 c4baxH_ 15 d1jx4a2 16 c2d3aJ_ 17 c3ebkA_ 18 c4is4G_ 19 c4kl0A_ 20 c5yrzD_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99