1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	F	P	V	V	L	D	A	C	V	L	V	P	H	P	L	V	D	A	L	L	R	F	A	D	E	G	T	Y	R	P	L	W	S	E	D	I	L	A	E	T	R	R	T	M	V	D	R	L	N	I	S	T	E	R	A	D	Y	R
Secondary structure
SS confidence
Disorder		?	?	?																																															?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.
Sequence		I	R	F	R	V	Q	R	P	H	R	R	H	E	Q	P	L	Q	R	S	T	C	A	S	C	S	G	P	R	A	R	G	G	D	S	H	D	K	P	Q	A	L	P
Secondary structure
SS confidence
Disorder									?					?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 37%) Alpha helix ( 52%) Beta strand ( 5%)

Rank Aligned region

PDB 2hww chain C Region: 2 - 64 Aligned: 58 Modelled: 63 Confidence: 63.6% Identity: 21% PDB header:rna binding protein Chain: C: PDB Molecule:telomerase-binding protein est1a; PDBTitle: structure of pin domain of human smg6 Phyre2 PDB 2fe1 chain A domain 1 Region: 4 - 101 Aligned: 98 Modelled: 98 Confidence: 59.2% Identity: 9% Fold: PIN domain-like Superfamily: PIN domain-like Family: PIN domain Phyre2 PDB 2fe1 chain A Region: 4 - 101 Aligned: 98 Modelled: 98 Confidence: 59.2% Identity: 9% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein pae0151; PDBTitle: crystal structure of pae0151 from pyrobaculum aerophilum Phyre2 PDB 6a7v chain G Region: 4 - 101 Aligned: 96 Modelled: 98 Confidence: 57.0% Identity: 13% PDB header:toxin/antitoxin Chain: G: PDB Molecule:ribonuclease vapc11; PDBTitle: crystal structure of mycobacterium tuberculosis vapbc11 toxin-2 antitoxin complex Phyre2 PDB 3ix7 chain A Region: 6 - 61 Aligned: 53 Modelled: 56 Confidence: 50.2% Identity: 23% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein ttha0540; PDBTitle: crystal structure of a domain of functionally unknown protein from2 thermus thermophilus hb8 Phyre2 PDB 5jpq chain D Region: 2 - 44 Aligned: 43 Modelled: 43 Confidence: 45.0% Identity: 19% PDB header:ribosome Chain: D: PDB Molecule:wd40 domain proteins; PDBTitle: cryo-em structure of the 90s pre-ribosome Phyre2 PDB 4ndk chain A Region: 41 - 76 Aligned: 28 Modelled: 36 Confidence: 40.6% Identity: 39% PDB header:fluorescent protein, de novo protein Chain: A: PDB Molecule:e23p-yfp, gfp-like fluorescent chromoprotein fp506, PDBTitle: crystal structure of a computational designed engrailed homeodomain2 variant fused with yfp Phyre2 PDB 3tnd chain C Region: 4 - 101 Aligned: 98 Modelled: 98 Confidence: 39.6% Identity: 9% PDB header:translation, toxin Chain: C: PDB Molecule:trna(fmet)-specific endonuclease vapc; PDBTitle: crystal structure of shigella flexneri vapbc toxin-antitoxin complex Phyre2 PDB 1v8p chain A Region: 4 - 89 Aligned: 86 Modelled: 86 Confidence: 38.2% Identity: 8% Fold: PIN domain-like Superfamily: PIN domain-like Family: PIN domain Phyre2 PDB 3i8o chain A Region: 4 - 64 Aligned: 59 Modelled: 61 Confidence: 37.7% Identity: 14% PDB header:rna binding protein Chain: A: PDB Molecule:kh domain-containing protein mj1533; PDBTitle: a domain of a functionally unknown protein from methanocaldococcus2 jannaschii dsm 2661. Phyre2 PDB 1o4w chain A Region: 4 - 85 Aligned: 81 Modelled: 82 Confidence: 36.9% Identity: 15% Fold: PIN domain-like Superfamily: PIN domain-like Family: PIN domain Phyre2 PDB 4ndl chain C Region: 41 - 62 Aligned: 22 Modelled: 22 Confidence: 35.3% Identity: 32% PDB header:de novo protein Chain: C: PDB Molecule:enh-c2b, computational designed homodimer; PDBTitle: computational design and experimental verification of a symmetric2 homodimer Phyre2 PDB 5yz4 chain A Region: 2 - 44 Aligned: 43 Modelled: 43 Confidence: 33.8% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:rrna-processing protein fcf1; PDBTitle: structure of the pin domain endonuclease utp24 Phyre2 PDB 1v8p chain K Region: 4 - 100 Aligned: 96 Modelled: 97 Confidence: 32.1% Identity: 9% PDB header:structural genomics, unknown function Chain: K: PDB Molecule:hypothetical protein pae2754; PDBTitle: crystal structure of pae2754 from pyrobaculum aerophilum Phyre2 PDB 5wzf chain B Region: 4 - 51 Aligned: 48 Modelled: 48 Confidence: 25.1% Identity: 17% PDB header:hydrolase Chain: B: PDB Molecule:23s rrna-specific endonuclease vapc20; PDBTitle: crystal structure of mycobacterium tuberculosis vapc20 (rv2549c),2 sarcin-ricin loop cleaving toxin Phyre2 PDB 4mj7 chain B Region: 2 - 44 Aligned: 43 Modelled: 43 Confidence: 21.4% Identity: 7% PDB header:rna binding protein Chain: B: PDB Molecule:rrna-processing protein utp23; PDBTitle: crystal structure of the pin domain of saccharomyces cerevisiae utp23 Phyre2 PDB 1v96 chain A domain 1 Region: 1 - 12 Aligned: 12 Modelled: 12 Confidence: 16.2% Identity: 25% Fold: PIN domain-like Superfamily: PIN domain-like Family: PIN domain Phyre2 PDB 1g3w chain A domain 2 Region: 42 - 93 Aligned: 49 Modelled: 52 Confidence: 16.0% Identity: 12% Fold: Iron-dependent repressor protein, dimerization domain Superfamily: Iron-dependent repressor protein, dimerization domain Family: Iron-dependent repressor protein, dimerization domain Phyre2 PDB 5npv chain B Region: 31 - 44 Aligned: 14 Modelled: 14 Confidence: 11.9% Identity: 43% PDB header:cell cycle Chain: B: PDB Molecule:autophagy-related protein 16-1; PDBTitle: structure of human atg5-atg16l1(atg5bd) complex (i4) Phyre2 PDB 5npw chain F Region: 31 - 44 Aligned: 14 Modelled: 14 Confidence: 11.8% Identity: 43% PDB header:cell cycle Chain: F: PDB Molecule:autophagy-related protein 16-1; PDBTitle: structure of human atg5-atg16l1(atg5bd) complex (c2) Phyre2 1 c2hwwC_ 2 d2fe1a1 3 c2fe1A_ 4 c6a7vG_ 5 c3ix7A_ 6 c5jpqd_ 7 c4ndkA_ 8 c3tndC_ 9 d1v8pa_ 10 c3i8oA_ 11 d1o4wa_ 12 c4ndlC_ 13 c5yz4A_ 14 c1v8pK_ 15 c5wzfB_ 16 c4mj7B_ 17 d1v96a1 18 d1g3wa2 19 c5npvB_ 20 c5npwF_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41