1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	Q	R	P	A	A	D	T	P	D	G	F	G	V	A	V	V	R	E	E	G	R	W	R	C	S	P	M	G	P	K	A	L	T	S	L	R	A	A	E	T	E	L	R	E	L	R	S	A	G	A	V	F	G	L	L	D	V	D	D
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?		?																																				?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		E	F	F	V	I	V	R	P	A	P	S	G	T	R	L	L	L	S	D	A	T	A	A	L	D	Y	D	I	A	A	E	V	L	D	N	L	D	A	E	I	D	P	E	D	L	E	D	A	D	P	F	E	E	G	D	L	G	L	L	S
Secondary structure
SS confidence
Disorder																							?	?	?	?													?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.
Sequence		D	I	G	L	P	E	A	V	L	G	V	I	L	D	E	T	D	L	Y	A	D	E	Q	L	G	R	I	A	R	E	M	G	F	A	D	Q	L	S	A	V	I	D	R	L	G	R
Secondary structure
SS confidence
Disorder																	?																											?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 19%) Alpha helix ( 40%) Beta strand ( 20%)

Rank Aligned region

PDB 6b9r chain D Region: 117 - 152 Aligned: 36 Modelled: 36 Confidence: 20.0% Identity: 19% PDB header:oxidoreductase Chain: D: PDB Molecule:hydroxyethylphosphonate dioxygenase; PDBTitle: streptomyces albus hepd with substrate 2-hydroxyethylphosphonate (2-2 hep) and fe(ii) bound Phyre2 PDB 5lc5 chain E Region: 127 - 152 Aligned: 26 Modelled: 26 Confidence: 17.5% Identity: 12% PDB header:oxidoreductase Chain: E: PDB Molecule:nadh dehydrogenase [ubiquinone] flavoprotein 2, PDBTitle: structure of mammalian respiratory complex i, class2 Phyre2 PDB 1q1a chain A Region: 141 - 163 Aligned: 23 Modelled: 23 Confidence: 17.0% Identity: 17% Fold: DHS-like NAD/FAD-binding domain Superfamily: DHS-like NAD/FAD-binding domain Family: Sir2 family of transcriptional regulators Phyre2 PDB 6gcs chain H Region: 127 - 152 Aligned: 26 Modelled: 26 Confidence: 15.9% Identity: 8% PDB header:oxidoreductase Chain: H: PDB Molecule:24-kda subunit (nuhm); PDBTitle: cryo-em structure of respiratory complex i from yarrowia lipolytica Phyre2 PDB 5lnk chain 2 Region: 127 - 152 Aligned: 26 Modelled: 26 Confidence: 14.8% Identity: 12% PDB header:oxidoreductase Chain: 2: PDB Molecule:mitochondrial complex i, 24 kda subunit; PDBTitle: entire ovine respiratory complex i Phyre2 PDB 2fug chain 2 domain 1 Region: 127 - 152 Aligned: 26 Modelled: 26 Confidence: 12.9% Identity: 27% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: NQO2-like Phyre2 PDB 2l9f chain A Region: 115 - 153 Aligned: 28 Modelled: 39 Confidence: 11.7% Identity: 29% PDB header:transferase Chain: A: PDB Molecule:cale8; PDBTitle: nmr solution structure of meacp Phyre2 PDB 6f3t chain K Region: 138 - 164 Aligned: 27 Modelled: 27 Confidence: 11.5% Identity: 22% PDB header:transcription Chain: K: PDB Molecule:transcription initiation factor tfiid subunit 6; PDBTitle: crystal structure of the human taf5-taf6-taf9 complex Phyre2 PDB 3cm1 chain C Region: 64 - 115 Aligned: 50 Modelled: 52 Confidence: 11.3% Identity: 12% PDB header:cell cycle Chain: C: PDB Molecule:ssga-like sporulation-specific cell division protein; PDBTitle: crystal structure of ssga-like sporulation-specific cell division2 protein (yp_290167.1) from thermobifida fusca yx-er1 at 2.60 a3 resolution Phyre2 PDB 2mmp chain A Region: 53 - 68 Aligned: 16 Modelled: 16 Confidence: 11.3% Identity: 25% PDB header:ribosomal protein Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution structure of a ribosomal protein Phyre2 PDB 1bl0 chain A domain 2 Region: 144 - 156 Aligned: 13 Modelled: 13 Confidence: 11.1% Identity: 31% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: AraC type transcriptional activator Phyre2 PDB 6hl2 chain C Region: 127 - 152 Aligned: 26 Modelled: 26 Confidence: 10.4% Identity: 19% PDB header:electron transport Chain: C: PDB Molecule:nadh-quinone oxidoreductase subunit e; PDBTitle: wild-type nuoef from aquifex aeolicus - oxidized form Phyre2 PDB 5up5 chain A Region: 14 - 26 Aligned: 13 Modelled: 13 Confidence: 10.0% Identity: 54% PDB header:de novo protein Chain: A: PDB Molecule:ehee_rd1_0284; PDBTitle: solution structure of the de novo mini protein ehee_rd1_0284 Phyre2 PDB 3d0f chain A Region: 21 - 86 Aligned: 66 Modelled: 66 Confidence: 9.6% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:penicillin-binding 1 transmembrane protein mrca; PDBTitle: structure of the big_1156.2 domain of putative penicillin-binding2 protein mrca from nitrosomonas europaea atcc 19718 Phyre2 PDB 1d5y chain A domain 2 Region: 144 - 156 Aligned: 13 Modelled: 13 Confidence: 8.9% Identity: 31% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: AraC type transcriptional activator Phyre2 PDB 4h2u chain C Region: 112 - 132 Aligned: 18 Modelled: 21 Confidence: 7.7% Identity: 22% PDB header:ligase Chain: C: PDB Molecule:aminoacyl carrier protein 1; PDBTitle: crystal structure of bradyrhizobium japonicum glycine:[carrier2 protein] ligase complexed with cognate carrier protein and atp Phyre2 PDB 4yf1 chain D Region: 116 - 166 Aligned: 49 Modelled: 51 Confidence: 7.6% Identity: 16% PDB header:hydrolase Chain: D: PDB Molecule:lmo0812 protein; PDBTitle: 1.85 angstrom crystal structure of lmo0812 from listeria monocytogenes2 egd-e Phyre2 PDB 5vwx chain B Region: 141 - 159 Aligned: 19 Modelled: 19 Confidence: 7.5% Identity: 32% PDB header:apoptosis Chain: B: PDB Molecule:bcl-2-like protein 11; PDBTitle: bak core latch dimer in complex with bim-h0-h3glt Phyre2 PDB 1taf chain B Region: 138 - 164 Aligned: 27 Modelled: 27 Confidence: 6.8% Identity: 19% Fold: Histone-fold Superfamily: Histone-fold Family: TBP-associated factors, TAFs Phyre2 PDB 4dkk chain A Region: 140 - 153 Aligned: 14 Modelled: 14 Confidence: 6.6% Identity: 43% PDB header:rna binding protein Chain: A: PDB Molecule:double-stranded rna-binding protein staufen homolog 1; PDBTitle: the x-ray crystal structure of the human stau1 ssm-'rbd'5 domain-2 swapped dimer Phyre2 1 c6b9rD_ 2 c5lc5E_ 3 d1q1aa_ 4 c6gcsH_ 5 c5lnk2_ 6 d2fug21 7 c2l9fA_ 8 c6f3tK_ 9 c3cm1C_ 10 c2mmpA_ 11 d1bl0a2 12 c6hl2C_ 13 c5up5A_ 14 c3d0fA_ 15 d1d5ya2 16 c4h2uC_ 17 c4yf1D_ 18 c5vwxB_ 19 d1tafb_ 20 c4dkkA_ 21 22 23 24 25 26 27 28