1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	H	Y	L	M	T	H	P	G	A	A	W	A	L	T	V	V	H	L	R	L	S	L	L	P	V	L	I	G	L	M	S	A	V	P	L	G	L	L	V	Q	R	A	P	L	L	R	R	L	T	T	A	T	A	S	V	I	F	T	I
Secondary structure
SS confidence
Disorder		?	?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	S	L	A	L	F	V	V	L	P	L	I	I	G	T	R	I	L	D	E	A	N	V	I	V	A	L	A	A	Y	T	T	A	L	L	V	R	A	V	L	E	A	L	D	A	V	P	A	Q	V	H	D	A	A	T	A	I	G	Y	S
Secondary structure
SS confidence
Disorder																?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	I	A	Q	M	L	K	V	E	L	P	L	S	I	P	V	L	V	A	G	L	R	V	V	A	V	T	N	I	A	M	V	S	V	G	S	V	I	G	I	G	G	L	G	T	W	F	T	A	G	Y	Q	T	N	K	S	D	Q	I	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.
Sequence		A	G	V	V	A	M	F	L	L	A	I	V	V	D	V	V	I	N	L	A	G	R	L	A	T	P	W	E	R	A	P	R	A	A	R	R	R	R	Q	V	A	A	P	I	T	G	G	A	R
Secondary structure
SS confidence
Disorder																														?	?	?	?	?	?	?	?	?	?	?	?	?		?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 12%) Alpha helix ( 79%) Beta strand ( 0%) TM helix ( 54%) (View membrane topology prediction)

Rank Aligned region

PDB 4ymu chain C Region: 2 - 204 Aligned: 203 Modelled: 203 Confidence: 99.9% Identity: 17% PDB header:protein binding/transport protein Chain: C: PDB Molecule:abc-type amino acid transport system, permease component; PDBTitle: crystal structure of an amino acid abc transporter complex with2 arginines and atps Phyre2 PDB 2onk chain C domain 1 Region: 8 - 200 Aligned: 193 Modelled: 193 Confidence: 99.9% Identity: 19% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2onk chain C Region: 8 - 200 Aligned: 193 Modelled: 193 Confidence: 99.9% Identity: 19% PDB header:membrane protein Chain: C: PDB Molecule:molybdate/tungstate abc transporter, permease PDBTitle: abc transporter modbc in complex with its binding protein2 moda Phyre2 PDB 3d31 chain C domain 1 Region: 8 - 198 Aligned: 191 Modelled: 191 Confidence: 99.9% Identity: 18% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 3d31 chain D Region: 8 - 198 Aligned: 191 Modelled: 191 Confidence: 99.9% Identity: 18% PDB header:transport protein Chain: D: PDB Molecule:sulfate/molybdate abc transporter, permease protein; PDBTitle: modbc from methanosarcina acetivorans Phyre2 PDB 4tqv chain I Region: 7 - 206 Aligned: 200 Modelled: 200 Confidence: 99.9% Identity: 16% PDB header:transport protein Chain: I: PDB Molecule:algm1; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 3dhw chain A domain 1 Region: 11 - 198 Aligned: 188 Modelled: 188 Confidence: 99.9% Identity: 23% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2r6g chain F Region: 6 - 196 Aligned: 191 Modelled: 191 Confidence: 99.9% Identity: 18% PDB header:hydrolase/transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: the crystal structure of the e. coli maltose transporter Phyre2 PDB 2r6g chain F domain 2 Region: 6 - 196 Aligned: 191 Modelled: 191 Confidence: 99.9% Identity: 18% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 4tqv chain J Region: 7 - 206 Aligned: 199 Modelled: 200 Confidence: 99.9% Identity: 15% PDB header:transport protein Chain: J: PDB Molecule:algm2; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 3fh6 chain F Region: 6 - 210 Aligned: 205 Modelled: 205 Confidence: 99.9% Identity: 17% PDB header:transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: crystal structure of the resting state maltose transporter from e.2 coli Phyre2 PDB 2r6g chain G domain 1 Region: 2 - 198 Aligned: 197 Modelled: 197 Confidence: 99.8% Identity: 17% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 5kbu chain A Region: 13 - 218 Aligned: 170 Modelled: 170 Confidence: 93.3% Identity: 14% PDB header:transport protein Chain: A: PDB Molecule:glutamate receptor 2,voltage-dependent calcium channel PDBTitle: cryo-em structure of glua2-2xstz complex at 7.8 angstrom resolution Phyre2 PDB 2m8g chain X Region: 98 - 128 Aligned: 31 Modelled: 31 Confidence: 32.8% Identity: 23% PDB header:transcription Chain: X: PDB Molecule:transcriptional regulator; PDBTitle: structure, function, and tethering of dna-binding domains in 542 transcriptional activators Phyre2 PDB 1umq chain A Region: 98 - 128 Aligned: 31 Modelled: 31 Confidence: 28.8% Identity: 10% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 1umq chain A Region: 98 - 128 Aligned: 31 Modelled: 31 Confidence: 28.8% Identity: 10% PDB header:dna-binding protein Chain: A: PDB Molecule:photosynthetic apparatus regulatory protein; PDBTitle: solution structure and dna binding of the effector domain2 from the global regulator prra(rega) from r. sphaeroides:3 insights into dna binding specificity Phyre2 PDB 1ntc chain A Region: 97 - 128 Aligned: 32 Modelled: 32 Confidence: 28.4% Identity: 19% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 4l5e chain A Region: 97 - 128 Aligned: 32 Modelled: 32 Confidence: 27.1% Identity: 13% PDB header:protein binding Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: crystal structure of a. aeolicus ntrc1 dna binding domain Phyre2 PDB 1fip chain A Region: 98 - 128 Aligned: 31 Modelled: 31 Confidence: 18.0% Identity: 16% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 1eto chain B Region: 97 - 128 Aligned: 32 Modelled: 32 Confidence: 15.4% Identity: 16% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 1 c4ymuC_ 2 d2onkc1 3 c2onkC_ 4 d3d31c1 5 c3d31D_ 6 c4tqvI_ 7 d3dhwa1 8 c2r6gF_ 9 d2r6gf2 10 c4tqvJ_ 11 c3fh6F_ 12 d2r6gg1 13 c5kbuA_ 14 c2m8gX_ 15 d1umqa_ 16 c1umqA_ 17 d1ntca_ 18 c4l5eA_ 19 d1fipa_ 20 d1etob_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37