1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	G	S	T	P	W	C	P	N	P	C	Q	C	T	L	R	T	P	V	E	V	L	E	L	A	V	A	L	R	P	E	N	P	D	R	T	A	G	A	I	Q	R	I	L	R	A	Q	L	A	G	D	R	I	A	L	R	G	R	G	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																									?		?	?	?	?													?	?		?			?	?	?	?	?	?
Disorder confidence
Sequence
Secondary structure
SS confidence
Disorder
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 33%) Alpha helix ( 42%) Beta strand ( 13%)

Rank Aligned region

PDB 1xku chain A Region: 5 - 17 Aligned: 13 Modelled: 13 Confidence: 72.7% Identity: 62% Fold: Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) Superfamily: L domain-like Family: Ngr ectodomain-like Phyre2 PDB 1xku chain A Region: 5 - 17 Aligned: 13 Modelled: 13 Confidence: 72.7% Identity: 62% PDB header:structural protein Chain: A: PDB Molecule:decorin; PDBTitle: crystal structure of the dimeric protein core of decorin, the2 archetypal small leucine-rich repeat proteoglycan Phyre2 PDB 3j32 chain B Region: 2 - 10 Aligned: 9 Modelled: 9 Confidence: 45.6% Identity: 67% PDB header:oxygen transport Chain: B: PDB Molecule:hemocyanin isoform 1; PDBTitle: an asymmetric unit map from electron cryo-microscopy of haliotis2 diversicolor molluscan hemocyanin isoform 1 (hdh1) Phyre2 PDB 4wal chain A Region: 47 - 60 Aligned: 14 Modelled: 14 Confidence: 43.2% Identity: 50% PDB header:protein binding/rna Chain: A: PDB Molecule:branchpoint-bridging protein; PDBTitle: crystal structure of selenomethionine msl5 protein in complex with rna2 at 2.2 a Phyre2 PDB 2bl5 chain A domain 1 Region: 47 - 60 Aligned: 14 Modelled: 14 Confidence: 35.7% Identity: 43% Fold: Eukaryotic type KH-domain (KH-domain type I) Superfamily: Eukaryotic type KH-domain (KH-domain type I) Family: Eukaryotic type KH-domain (KH-domain type I) Phyre2 PDB 4jvh chain A Region: 38 - 60 Aligned: 22 Modelled: 23 Confidence: 35.2% Identity: 41% PDB header:rna binding protein Chain: A: PDB Molecule:protein quaking; PDBTitle: structure of the star domain of quaking protein in complex with rna Phyre2 PDB 4bst chain B Region: 7 - 13 Aligned: 7 Modelled: 7 Confidence: 31.8% Identity: 57% PDB header:signaling protein Chain: B: PDB Molecule:leucine-rich repeat-containing g-protein coupled receptor PDBTitle: structure of the ectodomain of lgr5 in complex with r-spondin-12 (fu1fu2) in p6122 crystal form Phyre2 PDB 1k1g chain A Region: 47 - 60 Aligned: 14 Modelled: 14 Confidence: 31.5% Identity: 36% Fold: Eukaryotic type KH-domain (KH-domain type I) Superfamily: Eukaryotic type KH-domain (KH-domain type I) Family: Eukaryotic type KH-domain (KH-domain type I) Phyre2 PDB 2phn chain A domain 1 Region: 26 - 48 Aligned: 23 Modelled: 23 Confidence: 29.4% Identity: 26% Fold: CofE-like Superfamily: CofE-like Family: CofE-like Phyre2 PDB 5el3 chain D Region: 47 - 60 Aligned: 14 Modelled: 14 Confidence: 28.2% Identity: 21% PDB header:rna binding protein Chain: D: PDB Molecule:kh domain-containing, rna-binding, signal transduction- PDBTitle: structure of the kh domain of t-star Phyre2 PDB 1myk chain A Region: 12 - 53 Aligned: 42 Modelled: 42 Confidence: 26.9% Identity: 36% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: Arc/Mnt-like phage repressors Phyre2 PDB 4pbw chain B Region: 7 - 17 Aligned: 11 Modelled: 11 Confidence: 26.4% Identity: 36% PDB header:signaling protein Chain: B: PDB Molecule:nt-3 growth factor receptor; PDBTitle: crystal structure of chicken receptor protein tyrosine phosphatase2 sigma in complex with trkc Phyre2 PDB 1baz chain A Region: 12 - 53 Aligned: 42 Modelled: 42 Confidence: 26.1% Identity: 36% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: Arc/Mnt-like phage repressors Phyre2 PDB 4u7l chain A Region: 7 - 17 Aligned: 11 Modelled: 11 Confidence: 24.7% Identity: 36% PDB header:signaling protein Chain: A: PDB Molecule:leucine-rich repeats and immunoglobulin-like domains PDBTitle: lrig1 extracellular domain: structure and function analysis Phyre2 PDB 5elt chain B Region: 47 - 60 Aligned: 14 Modelled: 14 Confidence: 23.6% Identity: 21% PDB header:rna binding protein Chain: B: PDB Molecule:kh domain-containing, rna-binding, signal transduction- PDBTitle: structure of the qua1-kh domain of t-star in complex with uaau rna Phyre2 PDB 1bdt chain A Region: 12 - 53 Aligned: 42 Modelled: 42 Confidence: 23.2% Identity: 36% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: Arc/Mnt-like phage repressors Phyre2 PDB 4jvy chain A Region: 47 - 60 Aligned: 14 Modelled: 14 Confidence: 20.7% Identity: 50% PDB header:rna binding protein Chain: A: PDB Molecule:female germline-specific tumor suppressor gld-1; PDBTitle: structure of the star (signal transduction and activation of rna)2 domain of gld-1 bound to rna Phyre2 PDB 4qxe chain A Region: 5 - 14 Aligned: 10 Modelled: 10 Confidence: 20.5% Identity: 50% PDB header:membrane protein Chain: A: PDB Molecule:leucine-rich repeat-containing g-protein coupled receptor PDBTitle: crystal structure of lgr4 fused with hagfish vlr Phyre2 PDB 4qdh chain A Region: 7 - 17 Aligned: 11 Modelled: 11 Confidence: 20.1% Identity: 36% PDB header:immune system Chain: A: PDB Molecule:variable lymphocyte receptor b, toll-like receptor 9 PDBTitle: crystal structure of the c-terminal domain of mouse tlr9 Phyre2 PDB 4kt1 chain A Region: 5 - 14 Aligned: 10 Modelled: 10 Confidence: 19.9% Identity: 50% PDB header:hormone receptor/cell adhesion Chain: A: PDB Molecule:leucine-rich repeat-containing g-protein coupled receptor PDBTitle: complex of r-spondin 1 with lgr4 extracellular domain Phyre2 1 d1xkua_ 2 c1xkuA_ 3 c3j32B_ 4 c4walA_ 5 d2bl5a1 6 c4jvhA_ 7 c4bstB_ 8 d1k1ga_ 9 d2phna1 10 c5el3D_ 11 d1myka_ 12 c4pbwB_ 13 d1baza_ 14 c4u7lA_ 15 c5eltB_ 16 d1bdta_ 17 c4jvyA_ 18 c4qxeA_ 19 c4qdhA_ 20 c4kt1A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99