1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	G	L	W	F	G	T	L	I	A	L	I	L	L	I	A	P	G	A	M	V	A	R	I	A	Q	L	R	W	P	V	A	I	A	V	G	P	A	L	T	Y	G	V	V	A	L	A	I	I	P	Y	G	A	L	G	I	P	W	N	G
Secondary structure
SS confidence
Disorder		?	?	?																						?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		W	T	A	L	A	A	L	A	V	T	C	A	V	A	T	G	L	Q	L	L	L	A	R	F	R	D	L	D	A	E	A	L	A	V	S	R	W	P	A	V	T	V	A	A	G	V	L	L	G	A	L	L	I	G	W	A	A	Y	R	G
Secondary structure
SS confidence
Disorder																								?		?	?	?	?	?	?	?	?	?	?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	P	H	W	Q	S	I	P	S	T	W	D	A	V	W	H	A	N	T	V	R	F	I	L	D	T	G	Q	A	S	S	T	H	M	G	E	L	R	N	V	E	T	H	A	P	L	Y	Y	P	S	V	F	H	G	L	V	A	V	F	C
Secondary structure
SS confidence
Disorder			?	?																																		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Q	L	T	G	A	A	P	T	T	G	Y	T	L	S	S	L	A	A	S	V	W	L	F	P	V	S	A	A	V	L	T	W	R	A	V	R	S	H	P	G	A	L	W	S	A	S	C	A	S	A	E	W	R	A	A	G	A	A	G	T
Secondary structure
SS confidence
Disorder			?	?	?	?																															?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	A	A	L	S	A	S	F	T	A	V	P	Y	V	E	F	D	T	A	A	M	P	N	L	A	A	Y	G	I	A	V	P	T	M	V	L	I	T	S	T	L	R	H	R	D	R	I	P	V	A	V	L	A	L	V	G	V	F	S	L
Secondary structure
SS confidence
Disorder																																							?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		H	I	T	G	G	I	V	V	A	L	L	V	S	A	W	W	L	F	E	A	L	R	H	P	V	R	S	R	L	A	D	L	L	T	L	A	G	V	A	A	M	A	G	L	V	M	L	P	Q	F	L	S	V	R	Q	Q	E	D	I	I
Secondary structure
SS confidence
Disorder																							?	?	?	?	?	?	?	?	?	?																					?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		A	G	H	A	F	P	T	Y	L	S	K	K	R	G	L	F	D	A	V	F	Q	H	S	R	H	L	N	D	F	P	V	Q	Y	A	L	I	V	L	A	A	I	G	G	L	I	L	L	V	K	K	I	W	W	P	L	A	V	W	L	L
Secondary structure
SS confidence
Disorder		?	?	?				?																		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		L	I	V	M	N	V	D	A	G	T	P	L	G	G	P	I	G	G	V	A	G	A	L	G	E	F	F	Y	H	D	P	R	R	I	A	A	A	T	T	L	L	L	M	L	M	A	G	V	A	L	F	A	T	V	M	L	L	V	A	A
Secondary structure
SS confidence
Disorder											?			?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		A	K	R	L	T	D	R	F	R	P	Q	P	V	S	V	W	A	S	A	T	A	T	L	L	I	G	A	T	L	V	S	A	W	H	Y	F	P	R	H	R	F	L	F	G	D	K	Y	D	S	V	M	I	D	Q	K	D	L	D	A	M
Secondary structure
SS confidence
Disorder				?	?	?	?	?	?	?	?	?																					?							?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence		A	Y	L	A	S	L	P	G	A	R	D	T	L	I	G	N	A	N	T	D	G	T	A	W	M	Y	A	V	A	G	L	H	P	L	W	T	H	Y	D	Y	P	L	Q	Q	G	P	G	Y	H	R	F	I	F	W	A	Y	G	R	N	G
Secondary structure
SS confidence
Disorder																																									?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence		E	S	D	P	R	V	L	E	A	I	Q	V	L	R	I	R	Y	I	L	T	S	T	P	T	V	R	G	F	A	V	P	D	G	L	V	S	L	E	T	S	R	S	W	A	K	I	Y	D	N	G	E	A	R	I	Y	E	W	R	G	T
Secondary structure
SS confidence
Disorder																										?	?																																		?
Disorder confidence
		.	.	.	.	.	.
Sequence		A	A	A	T	H	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 18%) Alpha helix ( 66%) Beta strand ( 3%) TM helix ( 45%) (View membrane topology prediction)

Rank Aligned region

PDB 6ezn chain F Region: 102 - 666 Aligned: 516 Modelled: 527 Confidence: 99.9% Identity: 14% PDB header:membrane protein Chain: F: PDB Molecule:dolichyl-diphosphooligosaccharide--protein PDBTitle: cryo-em structure of the yeast oligosaccharyltransferase (ost) complex Phyre2 PDB 3waj chain A Region: 100 - 621 Aligned: 468 Modelled: 494 Confidence: 99.8% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:transmembrane oligosaccharyl transferase; PDBTitle: crystal structure of the archaeoglobus fulgidus2 oligosaccharyltransferase (o29867_arcfu) complex with zn and sulfate Phyre2 PDB 3rce chain A Region: 103 - 617 Aligned: 434 Modelled: 457 Confidence: 99.6% Identity: 12% PDB header:transferase/peptide Chain: A: PDB Molecule:oligosaccharide transferase to n-glycosylate proteins; PDBTitle: bacterial oligosaccharyltransferase pglb Phyre2 PDB 5f15 chain A Region: 107 - 663 Aligned: 516 Modelled: 542 Confidence: 99.4% Identity: 11% PDB header:transferase Chain: A: PDB Molecule:4-amino-4-deoxy-l-arabinose (l-ara4n) transferase; PDBTitle: crystal structure of arnt from cupriavidus metallidurans bound to2 undecaprenyl phosphate Phyre2 PDB 3vu0 chain B Region: 532 - 658 Aligned: 116 Modelled: 126 Confidence: 98.5% Identity: 15% PDB header:transferase Chain: B: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of the c-terminal globular domain of2 oligosaccharyltransferase (afaglb-s2, af_0040, o30195_arcfu) from3 archaeoglobus fulgidus Phyre2 PDB 3vgp chain A Region: 529 - 660 Aligned: 121 Modelled: 129 Confidence: 98.3% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:transmembrane oligosaccharyl transferase, putative; PDBTitle: crystal structure of the c-terminal globular domain of2 oligosaccharyltransferase (af_0329) from archaeoglobus fulgidus Phyre2 PDB 6p2r chain B Region: 105 - 356 Aligned: 224 Modelled: 225 Confidence: 96.3% Identity: 13% PDB header:transferase Chain: B: PDB Molecule:dolichyl-phosphate-mannose--protein mannosyltransferase 2; PDBTitle: structure of s. cerevisiae protein o-mannosyltransferase pmt1-pmt22 complex bound to the sugar donor Phyre2 PDB 6p25 chain A Region: 105 - 356 Aligned: 218 Modelled: 218 Confidence: 95.5% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:dolichyl-phosphate-mannose--protein mannosyltransferase 1; PDBTitle: structure of s. cerevisiae protein o-mannosyltransferase pmt1-pmt22 complex bound to the sugar donor and a peptide acceptor Phyre2 PDB 2lgz chain A Region: 509 - 620 Aligned: 103 Modelled: 112 Confidence: 94.2% Identity: 11% PDB header:transferase, membrane protein Chain: A: PDB Molecule:dolichyl-diphosphooligosaccharide--protein PDBTitle: solution structure of stt3p Phyre2 PDB 3wai chain A Region: 537 - 621 Aligned: 81 Modelled: 85 Confidence: 92.6% Identity: 16% PDB header:transferase, transport protein Chain: A: PDB Molecule:maltose-binding periplasmic protein, transmembrane PDBTitle: crystal structure of the c-terminal globular domain of2 oligosaccharyltransferase (afaglb-l, o29867_arcfu) from archaeoglobus3 fulgidus as a mbp fusion Phyre2 PDB 3vu1 chain A Region: 537 - 664 Aligned: 107 Modelled: 128 Confidence: 83.0% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:putative uncharacterized protein ph0242; PDBTitle: crystal structure of the c-terminal globular domain of2 oligosaccharyltransferase (phaglb-l, o74088_pyrho) from pyrococcus3 horikoshii Phyre2 PDB 2nac chain A Region: 553 - 638 Aligned: 86 Modelled: 86 Confidence: 67.5% Identity: 13% PDB header:oxidoreductase(aldehyde(d),nad+(a)) Chain: A: PDB Molecule:nad-dependent formate dehydrogenase; PDBTitle: high resolution structures of holo and apo formate dehydrogenase Phyre2 PDB 5svb chain D Region: 538 - 575 Aligned: 38 Modelled: 38 Confidence: 57.2% Identity: 16% PDB header:ligase Chain: D: PDB Molecule:acetone carboxylase alpha subunit; PDBTitle: mechanism of atp-dependent acetone carboxylation, acetone carboxylase2 amp bound structure Phyre2 PDB 5l9w chain A Region: 537 - 575 Aligned: 39 Modelled: 39 Confidence: 55.8% Identity: 10% PDB header:ligase Chain: A: PDB Molecule:acetophenone carboxylase delta subunit; PDBTitle: crystal structure of the apc core complex Phyre2 PDB 3fn4 chain A Region: 553 - 638 Aligned: 86 Modelled: 86 Confidence: 52.4% Identity: 14% PDB header:oxidoreductase Chain: A: PDB Molecule:nad-dependent formate dehydrogenase; PDBTitle: apo-form of nad-dependent formate dehydrogenase from bacterium2 moraxella sp.c-1 in closed conformation Phyre2 PDB 2b5d chain X Region: 603 - 655 Aligned: 47 Modelled: 53 Confidence: 50.6% Identity: 4% PDB header:hydrolase Chain: X: PDB Molecule:alpha-amylase; PDBTitle: crystal structure of the novel alpha-amylase amyc from thermotoga2 maritima Phyre2 PDB 2nac chain A domain 2 Region: 553 - 638 Aligned: 86 Modelled: 86 Confidence: 46.5% Identity: 13% Fold: Flavodoxin-like Superfamily: Formate/glycerate dehydrogenase catalytic domain-like Family: Formate/glycerate dehydrogenases, substrate-binding domain Phyre2 PDB 2odg chain C domain 1 Region: 602 - 617 Aligned: 16 Modelled: 16 Confidence: 40.6% Identity: 19% Fold: LEM/SAP HeH motif Superfamily: LEM domain Family: LEM domain Phyre2 PDB 2hyx chain A Region: 601 - 659 Aligned: 54 Modelled: 59 Confidence: 35.8% Identity: 15% PDB header:unknown function Chain: A: PDB Molecule:protein dipz; PDBTitle: structure of the c-terminal domain of dipz from mycobacterium2 tuberculosis Phyre2 PDB 1c01 chain A Region: 642 - 665 Aligned: 24 Modelled: 24 Confidence: 34.8% Identity: 21% Fold: gamma-Crystallin-like Superfamily: gamma-Crystallin-like Family: Plant antimicrobial protein MIAMP1 Phyre2 1 c6eznF_ 2 c3wajA_ 3 c3rceA_ 4 c5f15A_ 5 c3vu0B_ 6 c3vgpA_ 7 c6p2rB_ 8 c6p25A_ 9 c2lgzA_ 10 c3waiA_ 11 c3vu1A_ 12 c2nacA_ 13 c5svbD_ 14 c5l9wA_ 15 c3fn4A_ 16 c2b5dX_ 17 d2naca2 18 d2odgc1 19 c2hyxA_ 20 d1c01a_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99