1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	E	D	V	V	T	Q	P	P	A	N	L	V	A	G	V	V	K	A	I	R	P	R	Q	W	V	K	N	V	L	V	L	A	A	P	L	A	A	L	G	G	G	V	R	Y	D	Y	V	E	V	L	S	K	V	S	M	A	F	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?																															?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	F	S	L	A	A	S	A	V	Y	L	V	N	D	V	R	D	V	E	A	D	R	E	H	P	T	K	R	F	R	P	I	A	A	G	V	V	P	E	W	L	A	Y	T	V	A	V	V	L	G	V	T	S	L	A	G	A	W	M	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	P	N	L	A	L	V	M	V	V	Y	L	A	M	Q	L	A	Y	C	F	G	L	K	H	Q	A	V	V	E	I	C	V	V	S	S	A	Y	L	I	R	A	I	A	G	G	V	A	T	K	I	P	L	S	K	W	F	L	L	I	M
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	F	G	S	L	F	M	V	A	G	K	R	Y	A	E	L	H	L	A	E	R	T	G	A	A	I	R	K	S	L	E	S	Y	T	S	T	Y	L	R	F	V	W	T	L	S	A	T	A	V	V	L	C	Y	G	L	W	A	F	E	R
Secondary structure
SS confidence
Disorder																					?	?	?	?	?	?	?	?																																?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		D	G	Y	S	G	S	W	F	A	V	S	M	I	P	F	T	I	A	I	L	R	Y	A	V	D	V	D	G	G	L	A	G	E	P	E	D	I	A	L	R	D	R	V	L	Q	L	L	A	L	A	W	I	A	T	V	G	A	A	V	A
Secondary structure
SS confidence
Disorder		?	?																									?	?		?
Disorder confidence
		.	.
Sequence		F	G
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 11%) Alpha helix ( 75%) Beta strand ( 0%) TM helix ( 57%) (View membrane topology prediction)

Rank Aligned region

PDB 4od5 chain C Region: 19 - 299 Aligned: 264 Modelled: 281 Confidence: 100.0% Identity: 15% PDB header:transferase Chain: C: PDB Molecule:4-hydroxybenzoate octaprenyltransferase; PDBTitle: substrate-bound structure of a ubia homolog from aeropyrum pernix k1 Phyre2 PDB 3dh4 chain A Region: 55 - 236 Aligned: 173 Modelled: 182 Confidence: 60.9% Identity: 12% PDB header:transport protein Chain: A: PDB Molecule:sodium/glucose cotransporter; PDBTitle: crystal structure of sodium/sugar symporter with bound galactose from2 vibrio parahaemolyticus Phyre2 PDB 2l4f chain A Region: 70 - 81 Aligned: 12 Modelled: 12 Confidence: 32.8% Identity: 42% PDB header:protein binding Chain: A: PDB Molecule:defective in cullin neddylation protein 1; PDBTitle: nmr structure of the uba domain of s. cerevisiae dcn1 bound to2 ubiquitin Phyre2 PDB 2xq2 chain A Region: 52 - 267 Aligned: 207 Modelled: 216 Confidence: 28.1% Identity: 12% PDB header:transport protein Chain: A: PDB Molecule:sodium/glucose cotransporter; PDBTitle: structure of the k294a mutant of vsglt Phyre2 PDB 1dih chain A domain 2 Region: 60 - 91 Aligned: 32 Modelled: 32 Confidence: 23.9% Identity: 28% Fold: FwdE/GAPDH domain-like Superfamily: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Family: Dihydrodipicolinate reductase-like Phyre2 PDB 5us6 chain L Region: 60 - 91 Aligned: 32 Modelled: 32 Confidence: 20.7% Identity: 31% PDB header:oxidoreductase Chain: L: PDB Molecule:4-hydroxy-tetrahydrodipicolinate reductase; PDBTitle: structure of dihydrodipicolinate reductase from vibrio vulnificus2 bound to nadh and 2,6 pyridine dicarboxylic acid with intact3 polyhistidine tag Phyre2 PDB 4o6m chain A Region: 75 - 268 Aligned: 180 Modelled: 180 Confidence: 16.9% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:af2299, a cdp-alcohol phosphotransferase; PDBTitle: structure of af2299, a cdp-alcohol phosphotransferase (cmp-bound) Phyre2 PDB 3npk chain B Region: 19 - 118 Aligned: 83 Modelled: 86 Confidence: 16.4% Identity: 18% PDB header:transferase Chain: B: PDB Molecule:geranyltranstransferase; PDBTitle: the crystal structure of geranyltranstransferase from campylobacter2 jejuni Phyre2 PDB 4ksn chain C Region: 73 - 101 Aligned: 24 Modelled: 29 Confidence: 14.3% Identity: 33% PDB header:structural genomics, unknown function Chain: C: PDB Molecule:sdbc; PDBTitle: c-terminal domain of sdbc protein from legionella pneumophila. Phyre2 PDB 5ten chain H Region: 60 - 91 Aligned: 32 Modelled: 32 Confidence: 13.2% Identity: 31% PDB header:oxidoreductase Chain: H: PDB Molecule:4-hydroxy-tetrahydrodipicolinate reductase; PDBTitle: structure of 4-hydroxy-tetrahydrodipicolinate reductase from vibrio2 vulnificus with 2,5 furan dicarboxylic and nadh with intact3 polyhistidine tag Phyre2 PDB 2ww9 chain O Region: 87 - 94 Aligned: 8 Modelled: 8 Confidence: 7.5% Identity: 38% PDB header:ribosome Chain: O: PDB Molecule:60s ribosomal protein l39; PDBTitle: cryo-em structure of the active yeast ssh1 complex bound to the yeast2 80s ribosome Phyre2 PDB 3m9u chain D Region: 36 - 211 Aligned: 170 Modelled: 173 Confidence: 7.4% Identity: 12% PDB header:transferase Chain: D: PDB Molecule:farnesyl-diphosphate synthase; PDBTitle: crystal structure of geranylgeranyl pyrophosphate synthase from2 lactobacillus brevis atcc 367 Phyre2 PDB 5wwo chain B Region: 9 - 39 Aligned: 31 Modelled: 31 Confidence: 7.3% Identity: 23% PDB header:rna binding protein Chain: B: PDB Molecule:essential nuclear protein 1; PDBTitle: crystal structure of enp1 Phyre2 PDB 1drw chain A Region: 60 - 91 Aligned: 32 Modelled: 32 Confidence: 7.2% Identity: 28% PDB header:oxidoreductase Chain: A: PDB Molecule:dihydrodipicolinate reductase; PDBTitle: escherichia coli dhpr/nhdh complex Phyre2 PDB 6g4w chain W Region: 9 - 41 Aligned: 33 Modelled: 33 Confidence: 7.0% Identity: 15% PDB header:ribosome Chain: W: PDB Molecule:40s ribosomal protein s15a; PDBTitle: cryo-em structure of a late human pre-40s ribosomal subunit - state a Phyre2 PDB 4heo chain A Region: 65 - 77 Aligned: 13 Modelled: 13 Confidence: 6.7% Identity: 31% PDB header:viral protein Chain: A: PDB Molecule:phosphoprotein; PDBTitle: hendra virus phosphoprotein c terminal domain Phyre2 PDB 2ogd chain B Region: 19 - 119 Aligned: 90 Modelled: 101 Confidence: 6.6% Identity: 14% PDB header:transferase Chain: B: PDB Molecule:farnesyl pyrophosphate synthase; PDBTitle: t. brucei farnesyl diphosphate synthase complexed with bisphosphonate2 bph-527 Phyre2 PDB 3ijp chain A Region: 60 - 91 Aligned: 32 Modelled: 32 Confidence: 6.4% Identity: 25% PDB header:oxidoreductase Chain: A: PDB Molecule:dihydrodipicolinate reductase; PDBTitle: crystal structure of dihydrodipicolinate reductase from bartonella2 henselae at 2.0a resolution Phyre2 PDB 1vm6 chain A domain 2 Region: 60 - 91 Aligned: 31 Modelled: 32 Confidence: 6.2% Identity: 26% Fold: FwdE/GAPDH domain-like Superfamily: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Family: Dihydrodipicolinate reductase-like Phyre2 PDB 2v6q chain B Region: 21 - 29 Aligned: 9 Modelled: 9 Confidence: 6.2% Identity: 33% PDB header:apoptosis Chain: B: PDB Molecule:bcl-2-like protein 11; PDBTitle: crystal structure of a bhrf-1 : bim bh3 complex Phyre2 1 c4od5C_ 2 c3dh4A_ 3 c2l4fA_ 4 c2xq2A_ 5 d1diha2 6 c5us6L_ 7 c4o6mA_ 8 c3npkB_ 9 c4ksnC_ 10 c5tenH_ 11 c2ww9O_ 12 c3m9uD_ 13 c5wwoB_ 14 c1drwA_ 15 c6g4ww_ 16 c4heoA_ 17 c2ogdB_ 18 c3ijpA_ 19 d1vm6a2 20 c2v6qB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37