1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	E	L	A	A	S	L	L	S	R	V	I	L	P	R	P	G	E	P	L	D	V	R	K	L	Y	L	E	E	S	T	T	N	A	R	R	A	H	A	P	T	R	T	S	L	Q	I	G	A	E	S	E	V	S	F	A	T	Y	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?									?	?	?	?													?	?	?	?	?						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		N	A	F	P	A	S	Y	W	R	R	W	T	T	C	K	S	V	V	L	R	V	Q	V	T	G	A	G	R	V	D	V	Y	R	T	K	A	T	G	A	R	I	F	V	E	G	H	D	F	T	G	T	E	D	Q	P	A	A	V	E	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		E	V	V	L	Q	P	F	E	D	G	G	W	V	W	F	D	I	T	T	D	T	A	V	T	L	H	S	G	G	W	Y	A	T	S	P	A	P	G	T	A	N	I	A	V	G	I	P	T	F	N	R	P	A	D	C	V	N	A	L	R
Secondary structure
SS confidence
Disorder																																		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		E	L	T	A	D	P	L	V	D	Q	V	I	G	A	V	I	V	P	D	Q	G	E	R	K	V	R	D	H	P	D	F	P	A	A	A	A	R	L	G	S	R	L	S	I	H	D	Q	P	N	L	G	G	S	G	G	Y	S	R	V	M
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		Y	E	A	L	K	N	T	D	C	Q	Q	I	L	F	M	D	D	D	I	R	L	E	P	D	S	I	L	R	V	L	A	M	H	R	F	A	K	A	P	M	L	V	G	G	Q	M	L	N	L	Q	E	P	S	H	L	H	I	M	G	E
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		V	V	D	R	S	I	F	M	W	T	A	A	P	H	A	E	Y	D	H	D	F	A	E	Y	P	L	N	D	N	N	S	R	S	K	L	L	H	R	R	I	D	V	D	Y	N	G	W	W	T	C	M	I	P	R	Q	V	A	E	E	L
Secondary structure
SS confidence
Disorder															?														?							?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		G	Q	P	L	P	L	F	I	K	W	D	D	A	D	Y	G	L	R	A	A	E	H	G	Y	P	T	V	T	L	P	G	A	A	I	W	H	M	A	W	S	D	K	D	D	A	I	D	W	Q	A	Y	F	H	L	R	N	R	L	V	V
Secondary structure
SS confidence
Disorder																																									?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		A	A	M	H	W	D	G	P	K	A	Q	V	I	G	L	V	R	S	H	L	K	A	T	L	K	H	L	A	C	L	E	Y	S	T	V	A	I	Q	N	K	A	I	D	D	F	L	A	G	P	E	H	I	F	S	I	L	E	S	A	L
Secondary structure
SS confidence
Disorder										?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		P	Q	V	H	R	I	R	K	S	Y	P	D	A	V	V	L	P	A	A	S	E	L	P	P	P	L	H	K	N	K	A	M	K	P	P	V	N	P	L	V	I	G	Y	R	L	A	R	G	I	M	H	N	L	T	A	A	N	P	Q	H
Secondary structure
SS confidence
Disorder																	?	?	?	?	?	?	?			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?										?		?		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence		H	R	R	P	E	F	N	V	P	T	Q	D	A	R	W	F	L	L	C	T	V	D	G	A	T	V	T	T	A	D	G	C	G	V	V	Y	R	Q	R	D	R	A	K	M	F	A	L	L	W	Q	S	L	R	R	Q	R	Q	L	L	K
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.
Sequence		R	F	E	E	M	R	R	I	Y	R	D	A	L	P	T	L	S	S	K	Q	K	W	E	T	A	L	L	P	A	A	N	Q	E	P	E	H	G
Secondary structure
SS confidence
Disorder														?		?															?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 13%) Alpha helix ( 36%) Beta strand ( 27%) TM helix ( 3%) (View membrane topology prediction)

Rank Aligned region

PDB 4fix chain A Region: 1 - 629 Aligned: 629 Modelled: 629 Confidence: 100.0% Identity: 100% PDB header:transferase Chain: A: PDB Molecule:udp-galactofuranosyl transferase glft2; PDBTitle: crystal structure of glft2 Phyre2 PDB 1xhb chain A Region: 156 - 397 Aligned: 230 Modelled: 242 Confidence: 100.0% Identity: 12% PDB header:transferase Chain: A: PDB Molecule:polypeptide n-acetylgalactosaminyltransferase 1; PDBTitle: the crystal structure of udp-galnac: polypeptide alpha-n-2 acetylgalactosaminyltransferase-t1 Phyre2 PDB 2ffu chain A Region: 156 - 423 Aligned: 251 Modelled: 268 Confidence: 100.0% Identity: 12% PDB header:transferase Chain: A: PDB Molecule:polypeptide n-acetylgalactosaminyltransferase 2; PDBTitle: crystal structure of human ppgalnact-2 complexed with udp and ea2 Phyre2 PDB 6e4r chain B Region: 155 - 397 Aligned: 231 Modelled: 243 Confidence: 100.0% Identity: 10% PDB header:transferase Chain: B: PDB Molecule:polypeptide n-acetylgalactosaminyltransferase 9; PDBTitle: crystal structure of the drosophila melanogaster polypeptide n-2 acetylgalactosaminyl transferase pgant9b Phyre2 PDB 2d7i chain A Region: 160 - 421 Aligned: 246 Modelled: 262 Confidence: 100.0% Identity: 12% PDB header:transferase Chain: A: PDB Molecule:polypeptide n-acetylgalactosaminyltransferase 10; PDBTitle: crystal structure of pp-galnac-t10 with udp, galnac and mn2+ Phyre2 PDB 5nqa chain A Region: 155 - 397 Aligned: 230 Modelled: 243 Confidence: 100.0% Identity: 10% PDB header:transferase Chain: A: PDB Molecule:polypeptide n-acetylgalactosaminyltransferase 4; PDBTitle: crystal structure of galnac-t4 in complex with the monoglycopeptide 3 Phyre2 PDB 6iwq chain E Region: 156 - 421 Aligned: 258 Modelled: 266 Confidence: 100.0% Identity: 12% PDB header:transferase Chain: E: PDB Molecule:n-acetylgalactosaminyltransferase 7; PDBTitle: crystal structure of galnac-t7 with mn2+ Phyre2 PDB 1xhb chain A domain 2 Region: 145 - 396 Aligned: 240 Modelled: 252 Confidence: 100.0% Identity: 10% Fold: Nucleotide-diphospho-sugar transferases Superfamily: Nucleotide-diphospho-sugar transferases Family: Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain Phyre2 PDB 3zf8 chain A Region: 152 - 397 Aligned: 237 Modelled: 246 Confidence: 100.0% Identity: 11% PDB header:transferase Chain: A: PDB Molecule:mannan polymerase complexes subunit mnn9; PDBTitle: crystal structure of saccharomyces cerevisiae mnn9 in2 complex with gdp and mn. Phyre2 PDB 2z86 chain D Region: 154 - 397 Aligned: 236 Modelled: 244 Confidence: 100.0% Identity: 12% PDB header:transferase Chain: D: PDB Molecule:chondroitin synthase; PDBTitle: crystal structure of chondroitin polymerase from escherichia coli2 strain k4 (k4cp) complexed with udp-glcua and udp Phyre2 PDB 6h4m chain A Region: 160 - 467 Aligned: 272 Modelled: 280 Confidence: 100.0% Identity: 10% PDB header:transferase Chain: A: PDB Molecule:probable ss-1,3-n-acetylglucosaminyltransferase; PDBTitle: tarp-udp-glcnac-3rbop Phyre2 PDB 5tz8 chain C Region: 161 - 467 Aligned: 263 Modelled: 277 Confidence: 99.9% Identity: 13% PDB header:transferase Chain: C: PDB Molecule:glycosyl transferase; PDBTitle: crystal structure of s. aureus tars Phyre2 PDB 4hg6 chain A Region: 153 - 423 Aligned: 241 Modelled: 253 Confidence: 99.9% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:cellulose synthase subunit a; PDBTitle: structure of a cellulose synthase - cellulose translocation2 intermediate Phyre2 PDB 3bcv chain A Region: 160 - 390 Aligned: 192 Modelled: 201 Confidence: 99.9% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:putative glycosyltransferase protein; PDBTitle: crystal structure of a putative glycosyltransferase from bacteroides2 fragilis Phyre2 PDB 5hea chain A Region: 160 - 463 Aligned: 267 Modelled: 283 Confidence: 99.9% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:putative glycosyltransferase (galt1); PDBTitle: cgt structure in hexamer Phyre2 PDB 6p61 chain D Region: 157 - 396 Aligned: 190 Modelled: 200 Confidence: 99.9% Identity: 14% PDB header:transferase Chain: D: PDB Molecule:glycosyltransferase; PDBTitle: structure of a glycosyltransferase from leptospira borgpetersenii2 serovar hardjo-bovis (strain jb197) Phyre2 PDB 1qg8 chain A Region: 160 - 418 Aligned: 218 Modelled: 227 Confidence: 99.9% Identity: 14% Fold: Nucleotide-diphospho-sugar transferases Superfamily: Nucleotide-diphospho-sugar transferases Family: Spore coat polysaccharide biosynthesis protein SpsA Phyre2 PDB 5z8b chain B Region: 162 - 395 Aligned: 189 Modelled: 208 Confidence: 99.9% Identity: 16% PDB header:transferase Chain: B: PDB Molecule:kfia protein; PDBTitle: truncated n-acetylglucosaminyl transferase kfia from e. coli k5 strain2 apo form Phyre2 PDB 3f1y chain C Region: 160 - 425 Aligned: 228 Modelled: 240 Confidence: 99.9% Identity: 13% PDB header:transferase Chain: C: PDB Molecule:mannosyl-3-phosphoglycerate synthase; PDBTitle: mannosyl-3-phosphoglycerate synthase from rubrobacter xylanophilus Phyre2 PDB 5mm1 chain A Region: 161 - 450 Aligned: 249 Modelled: 268 Confidence: 99.9% Identity: 12% PDB header:membrane protein Chain: A: PDB Molecule:dolichol monophosphate mannose synthase; PDBTitle: dolichyl phosphate mannose synthase in complex with gdp and dolichyl2 phosphate mannose Phyre2 1 c4fixA_ 2 c1xhbA_ 3 c2ffuA_ 4 c6e4rB_ 5 c2d7iA_ 6 c5nqaA_ 7 c6iwqE_ 8 d1xhba2 9 c3zf8A_ 10 c2z86D_ 11 c6h4mA_ 12 c5tz8C_ 13 c4hg6A_ 14 c3bcvA_ 15 c5heaA_ 16 c6p61D_ 17 d1qg8a_ 18 c5z8bB_ 19 c3f1yC_ 20 c5mm1A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118