1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	E	P	F	F	R	M	M	E	I	L	V	P	S	I	V	A	A	N	G	N	K	I	T	F	E	G	L	E	N	I	P	E	R	G	G	A	L	I	A	L	N	H	T	S	Y	V	D	W	V	P	A	S	I	A	A	H	H	R
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	R	R	L	R	F	M	I	K	A	E	M	Q	D	V	R	A	V	N	Y	V	I	K	H	A	Q	L	I	P	V	D	R	S	V	G	A	D	A	Y	A	V	A	V	Q	R	L	R	A	G	E	L	V	G	L	H	P	E	A	T	I
Secondary structure
SS confidence
Disorder																																		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		S	R	S	L	E	L	R	E	F	K	T	G	A	A	R	M	A	L	E	A	Q	V	P	I	I	P	M	I	V	W	G	A	H	R	I	W	P	K	D	H	P	K	N	L	F	R	N	K	I	P	I	V	A	A	I	G	S	P	V	R
Secondary structure
SS confidence
Disorder					?		?			?																																?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		P	E	G	N	A	E	Q	L	N	A	V	L	R	Q	A	M	N	A	I	L	Y	R	V	Q	E	E	Y	P	H	P	K	G	E	H	W	V	P	R	R	L	G	G	G	A	P	T	V	E	E	S	R	Q	L	R	I	A	E	L	A	K
Secondary structure
SS confidence
Disorder																																?	?							?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.
Sequence		R	R	Q	K	R	G	Y	D	G	V	T	S	S	R	R	S	Q	V	G	P	H
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 19%) Alpha helix ( 45%) Beta strand ( 14%) TM helix ( 6%) (View membrane topology prediction)

Rank Aligned region

PDB 5kym chain A Region: 3 - 207 Aligned: 195 Modelled: 205 Confidence: 100.0% Identity: 23% PDB header:transferase Chain: A: PDB Molecule:1-acyl-sn-glycerol-3-phosphate acyltransferase; PDBTitle: crystal structure of the 1-acyl-sn-glycerophosphate (lpa)2 acyltransferase, plsc, from thermotoga maritima Phyre2 PDB 5f34 chain A Region: 5 - 233 Aligned: 203 Modelled: 212 Confidence: 99.8% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:phosphatidylinositol mannoside acyltransferase; PDBTitle: crystal structure of membrane associated pata from mycobacterium2 smegmatis in complex with s-hexadecyl coenzyme a - p21 space group Phyre2 PDB 5knk chain B Region: 5 - 255 Aligned: 227 Modelled: 237 Confidence: 99.7% Identity: 17% PDB header:transferase Chain: B: PDB Molecule:lipid a biosynthesis lauroyl acyltransferase; PDBTitle: lipid a secondary acyltransferase lpxm from acinetobacter baumannii2 with catalytic residue substitution (e127a) Phyre2 PDB 1iuq chain A Region: 5 - 225 Aligned: 214 Modelled: 221 Confidence: 99.1% Identity: 14% Fold: Glycerol-3-phosphate (1)-acyltransferase Superfamily: Glycerol-3-phosphate (1)-acyltransferase Family: Glycerol-3-phosphate (1)-acyltransferase Phyre2 PDB 6g2d chain C Region: 42 - 146 Aligned: 78 Modelled: 80 Confidence: 35.5% Identity: 12% PDB header:ligase Chain: C: PDB Molecule:acetyl-coa carboxylase 1; PDBTitle: citrate-induced acetyl-coa carboxylase (acc-cit) filament at 5.4 a2 resolution Phyre2 PDB 4mxn chain B Region: 83 - 119 Aligned: 37 Modelled: 35 Confidence: 31.7% Identity: 8% PDB header:hydrolase Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a putative glycosyl hydrolase (parmer_00599) from2 parabacteroides merdae atcc 43184 at 1.95 a resolution Phyre2 PDB 3hkx chain A Region: 96 - 145 Aligned: 50 Modelled: 50 Confidence: 22.7% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:amidase; PDBTitle: crystal structure analysis of an amidase from nesterenkonia sp. Phyre2 PDB 2ov3 chain A Region: 72 - 147 Aligned: 68 Modelled: 76 Confidence: 21.9% Identity: 13% PDB header:transport protein Chain: A: PDB Molecule:periplasmic binding protein component of an abc type zinc PDBTitle: crystal structure of 138-173 znua deletion mutant plus zinc bound Phyre2 PDB 3zpp chain A Region: 83 - 119 Aligned: 37 Modelled: 37 Confidence: 20.3% Identity: 19% PDB header:cell adhesion Chain: A: PDB Molecule:cell wall surface anchor family protein; PDBTitle: structure of the streptococcus pneumoniae surface protein2 and adhesin pfba Phyre2 PDB 4cyy chain A Region: 96 - 145 Aligned: 50 Modelled: 50 Confidence: 19.4% Identity: 12% PDB header:hydrolase Chain: A: PDB Molecule:pantetheinase; PDBTitle: the structure of vanin-1: defining the link between metabolic disease,2 oxidative stress and inflammation Phyre2 PDB 3jur chain A Region: 83 - 119 Aligned: 37 Modelled: 37 Confidence: 18.5% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:exo-poly-alpha-d-galacturonosidase; PDBTitle: the crystal structure of a hyperthermoactive exopolygalacturonase from2 thermotoga maritima Phyre2 PDB 5olp chain B Region: 83 - 119 Aligned: 37 Modelled: 37 Confidence: 17.3% Identity: 19% PDB header:hydrolase Chain: B: PDB Molecule:pectate lyase; PDBTitle: galacturonidase Phyre2 PDB 1pq4 chain A Region: 72 - 147 Aligned: 68 Modelled: 76 Confidence: 17.1% Identity: 12% Fold: Chelatase-like Superfamily: "Helical backbone" metal receptor Family: TroA-like Phyre2 PDB 2e11 chain B Region: 85 - 145 Aligned: 61 Modelled: 61 Confidence: 16.0% Identity: 16% PDB header:hydrolase Chain: B: PDB Molecule:hydrolase; PDBTitle: the crystal structure of xc1258 from xanthomonas campestris: a cn-2 hydrolase superfamily protein with an arsenic adduct in the active3 site Phyre2 PDB 5kha chain A Region: 96 - 145 Aligned: 50 Modelled: 50 Confidence: 15.1% Identity: 12% PDB header:ligase Chain: A: PDB Molecule:glutamine-dependent nad+ synthetase; PDBTitle: structure of glutamine-dependent nad+ synthetase from acinetobacter2 baumannii in complex with adenosine diphosphate (adp) Phyre2 PDB 1r0l chain D Region: 88 - 147 Aligned: 54 Modelled: 60 Confidence: 15.0% Identity: 15% PDB header:oxidoreductase Chain: D: PDB Molecule:1-deoxy-d-xylulose 5-phosphate reductoisomerase; PDBTitle: 1-deoxy-d-xylulose 5-phosphate reductoisomerase from zymomonas mobilis2 in complex with nadph Phyre2 PDB 2ogw chain B Region: 72 - 147 Aligned: 68 Modelled: 76 Confidence: 14.5% Identity: 18% PDB header:transport protein Chain: B: PDB Molecule:high-affinity zinc uptake system protein znua PDBTitle: structure of abc type zinc transporter from e. coli Phyre2 PDB 5uyv chain A Region: 74 - 148 Aligned: 67 Modelled: 75 Confidence: 14.0% Identity: 18% PDB header:metal transport Chain: A: PDB Molecule:periplasmic chelated iron-binding protein yfea; PDBTitle: yfea ancillary sites that do not co-load with site 2 Phyre2 PDB 4hnv chain B Region: 42 - 146 Aligned: 78 Modelled: 80 Confidence: 12.9% Identity: 13% PDB header:ligase Chain: B: PDB Molecule:pyruvate carboxylase; PDBTitle: crystal structure of r54e mutant of s. aureus pyruvate carboxylase Phyre2 PDB 1v7z chain A Region: 100 - 151 Aligned: 52 Modelled: 52 Confidence: 12.5% Identity: 17% Fold: Creatininase Superfamily: Creatininase Family: Creatininase Phyre2 1 c5kymA_ 2 c5f34A_ 3 c5knkB_ 4 d1iuqa_ 5 c6g2dC_ 6 c4mxnB_ 7 c3hkxA_ 8 c2ov3A_ 9 c3zppA_ 10 c4cyyA_ 11 c3jurA_ 12 c5olpB_ 13 d1pq4a_ 14 c2e11B_ 15 c5khaA_ 16 c1r0lD_ 17 c2ogwB_ 18 c5uyvA_ 19 c4hnvB_ 20 d1v7za_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58