1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	E	P	T	Y	R	V	L	E	I	L	A	Q	L	L	V	L	A	T	G	T	R	I	T	Y	V	G	E	E	N	V	P	D	Q	G	G	A	V	V	A	I	N	H	T	S	Y	V	D	W	L	P	A	A	L	A	M	H	R	R
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	R	R	M	R	F	M	I	K	A	E	M	Q	R	V	R	L	V	N	F	L	I	R	H	T	R	T	I	P	V	D	R	G	A	G	G	S	A	Y	A	V	A	V	Q	R	L	R	E	G	E	L	V	G	V	Y	P	E	A	T	I
Secondary structure
SS confidence
Disorder																																		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		S	R	S	F	E	L	K	G	F	K	T	G	A	A	R	M	A	A	E	A	D	V	P	I	V	P	V	V	V	W	G	A	Q	R	I	W	T	K	D	H	P	R	Q	I	G	R	A	K	V	P	V	T	V	Q	V	G	R	P	L	R
Secondary structure
SS confidence
Disorder					?		?			?																													?		?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	A	A	G	I	E	Q	T	N	A	A	L	R	E	S	M	T	A	L	L	W	Q	A	Q	E	R	Y	P	H	P	A	G	A	Y	W	V	P	R	R	L	G	G	G	A	P	T	L	A	E	A	A	R	M	E	A	D	E	A	A	A
Secondary structure
SS confidence
Disorder																																?	?	?				?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.
Sequence		R	A	A	S	R	T	P	H	E	S	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 21%) Alpha helix ( 45%) Beta strand ( 15%) TM helix ( 6%) (View membrane topology prediction)

Rank Aligned region

PDB 5kym chain A Region: 5 - 207 Aligned: 193 Modelled: 203 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:1-acyl-sn-glycerol-3-phosphate acyltransferase; PDBTitle: crystal structure of the 1-acyl-sn-glycerophosphate (lpa)2 acyltransferase, plsc, from thermotoga maritima Phyre2 PDB 5f34 chain A Region: 1 - 207 Aligned: 192 Modelled: 192 Confidence: 99.8% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:phosphatidylinositol mannoside acyltransferase; PDBTitle: crystal structure of membrane associated pata from mycobacterium2 smegmatis in complex with s-hexadecyl coenzyme a - p21 space group Phyre2 PDB 5knk chain B Region: 1 - 228 Aligned: 205 Modelled: 212 Confidence: 99.6% Identity: 14% PDB header:transferase Chain: B: PDB Molecule:lipid a biosynthesis lauroyl acyltransferase; PDBTitle: lipid a secondary acyltransferase lpxm from acinetobacter baumannii2 with catalytic residue substitution (e127a) Phyre2 PDB 1iuq chain A Region: 30 - 205 Aligned: 171 Modelled: 176 Confidence: 99.0% Identity: 17% Fold: Glycerol-3-phosphate (1)-acyltransferase Superfamily: Glycerol-3-phosphate (1)-acyltransferase Family: Glycerol-3-phosphate (1)-acyltransferase Phyre2 PDB 4cyy chain A Region: 96 - 145 Aligned: 50 Modelled: 50 Confidence: 18.4% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:pantetheinase; PDBTitle: the structure of vanin-1: defining the link between metabolic disease,2 oxidative stress and inflammation Phyre2 PDB 1l8n chain A domain 1 Region: 171 - 244 Aligned: 74 Modelled: 74 Confidence: 13.0% Identity: 11% Fold: TIM beta/alpha-barrel Superfamily: (Trans)glycosidases Family: alpha-D-glucuronidase/Hyaluronidase catalytic domain Phyre2 PDB 5kha chain A Region: 96 - 145 Aligned: 50 Modelled: 50 Confidence: 11.6% Identity: 18% PDB header:ligase Chain: A: PDB Molecule:glutamine-dependent nad+ synthetase; PDBTitle: structure of glutamine-dependent nad+ synthetase from acinetobacter2 baumannii in complex with adenosine diphosphate (adp) Phyre2 PDB 1h41 chain A domain 1 Region: 171 - 244 Aligned: 74 Modelled: 74 Confidence: 11.5% Identity: 11% Fold: TIM beta/alpha-barrel Superfamily: (Trans)glycosidases Family: alpha-D-glucuronidase/Hyaluronidase catalytic domain Phyre2 PDB 3hkx chain A Region: 96 - 145 Aligned: 50 Modelled: 50 Confidence: 10.5% Identity: 12% PDB header:hydrolase Chain: A: PDB Molecule:amidase; PDBTitle: crystal structure analysis of an amidase from nesterenkonia sp. Phyre2 PDB 1mqr chain A Region: 171 - 244 Aligned: 74 Modelled: 74 Confidence: 9.8% Identity: 11% PDB header:hydrolase Chain: A: PDB Molecule:alpha-d-glucuronidase; PDBTitle: the crystal structure of alpha-d-glucuronidase (e386q) from bacillus2 stearothermophilus t-6 Phyre2 PDB 5vrh chain A Region: 97 - 145 Aligned: 49 Modelled: 49 Confidence: 9.5% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:apolipoprotein n-acyltransferase; PDBTitle: apolipoprotein n-acyltransferase c387s active site mutant Phyre2 PDB 1wx4 chain B Region: 21 - 56 Aligned: 36 Modelled: 36 Confidence: 8.8% Identity: 22% PDB header:oxidoreductase/metal transport Chain: B: PDB Molecule:melc; PDBTitle: crystal structure of the oxy-form of the copper-bound streptomyces2 castaneoglobisporus tyrosinase complexed with a caddie protein3 prepared by the addition of dithiothreitol Phyre2 PDB 1ems chain B Region: 96 - 146 Aligned: 51 Modelled: 51 Confidence: 8.8% Identity: 8% PDB header:antitumor protein Chain: B: PDB Molecule:nit-fragile histidine triad fusion protein; PDBTitle: crystal structure of the c. elegans nitfhit protein Phyre2 PDB 1gqk chain B Region: 171 - 244 Aligned: 74 Modelled: 74 Confidence: 8.7% Identity: 11% PDB header:hydrolase Chain: B: PDB Molecule:alpha-d-glucuronidase; PDBTitle: structure of pseudomonas cellulosa alpha-d-glucuronidase complexed2 with glucuronic acid Phyre2 PDB 1uf5 chain A Region: 96 - 145 Aligned: 50 Modelled: 49 Confidence: 7.8% Identity: 16% Fold: Carbon-nitrogen hydrolase Superfamily: Carbon-nitrogen hydrolase Family: Carbamilase Phyre2 PDB 1o59 chain A domain 2 Region: 112 - 122 Aligned: 11 Modelled: 11 Confidence: 7.5% Identity: 18% Fold: Galactose-binding domain-like Superfamily: Galactose-binding domain-like Family: Allantoicase repeat Phyre2 PDB 1aop chain A domain 2 Region: 111 - 144 Aligned: 34 Modelled: 34 Confidence: 7.3% Identity: 15% Fold: Ferredoxin-like Superfamily: Nitrite/Sulfite reductase N-terminal domain-like Family: Duplicated SiR/NiR-like domains 1 and 3 Phyre2 PDB 2q8z chain A domain 1 Region: 169 - 205 Aligned: 37 Modelled: 37 Confidence: 6.9% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Decarboxylase Phyre2 PDB 6ehr chain D Region: 28 - 43 Aligned: 16 Modelled: 16 Confidence: 6.9% Identity: 44% PDB header:signaling protein Chain: D: PDB Molecule:ragulator complex protein lamtor4; PDBTitle: the crystal structure of the human lamtor-raga ctd-ragc ctd complex Phyre2 PDB 1o59 chain A domain 1 Region: 111 - 122 Aligned: 12 Modelled: 12 Confidence: 5.9% Identity: 33% Fold: Galactose-binding domain-like Superfamily: Galactose-binding domain-like Family: Allantoicase repeat Phyre2 1 c5kymA_ 2 c5f34A_ 3 c5knkB_ 4 d1iuqa_ 5 c4cyyA_ 6 d1l8na1 7 c5khaA_ 8 d1h41a1 9 c3hkxA_ 10 c1mqrA_ 11 c5vrhA_ 12 c1wx4B_ 13 c1emsB_ 14 c1gqkB_ 15 d1uf5a_ 16 d1o59a2 17 d1aopa2 18 d2q8za1 19 c6ehrD_ 20 d1o59a1 21 22