1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	E	P	V	Y	G	T	V	I	R	L	A	R	L	S	W	R	I	Q	G	L	K	I	T	V	T	G	V	D	N	L	P	T	S	G	G	A	V	V	A	I	N	H	T	S	Y	L	D	F	T	F	A	G	L	P	A	Y	Q	Q	G
Secondary structure
SS confidence
Disorder		?	?	?																																																						?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	G	R	K	V	R	F	M	A	K	Q	E	V	F	D	H	K	I	T	G	P	I	M	R	S	L	R	H	I	P	V	D	R	Q	D	G	S	A	S	Y	D	A	A	V	R	M	L	K	A	G	E	L	V	G	V	Y	P	E	A	T
Secondary structure
SS confidence
Disorder																																			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	S	R	S	F	E	I	K	E	F	K	T	G	A	A	R	M	A	I	E	A	G	V	P	I	V	P	H	I	V	W	G	A	Q	R	I	W	T	K	D	R	P	K	K	L	F	R	P	K	V	P	V	T	I	V	V	G	E	R	I
Secondary structure
SS confidence
Disorder						?		?			?																																?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		E	P	T	L	P	T	A	E	L	N	G	L	L	H	S	R	M	Q	H	L	L	E	R	A	Q	E	L	Y	G	P	H	P	A	G	E	F	W	V	P	H	R	L	G	G	G	A	P	S	L	A	E	A	A	R	L	D	A	Q	E	A
Secondary structure
SS confidence
Disorder					?		?																										?	?		?						?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.
Sequence		A	V	R	A	A	R	R	A	Q	R	A	H	P	A	G	A	P	E	Q
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 22%) Alpha helix ( 46%) Beta strand ( 14%) TM helix ( 6%) (View membrane topology prediction)

Rank Aligned region

PDB 5kym chain A Region: 4 - 208 Aligned: 193 Modelled: 205 Confidence: 100.0% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:1-acyl-sn-glycerol-3-phosphate acyltransferase; PDBTitle: crystal structure of the 1-acyl-sn-glycerophosphate (lpa)2 acyltransferase, plsc, from thermotoga maritima Phyre2 PDB 5f34 chain A Region: 22 - 208 Aligned: 171 Modelled: 172 Confidence: 99.7% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:phosphatidylinositol mannoside acyltransferase; PDBTitle: crystal structure of membrane associated pata from mycobacterium2 smegmatis in complex with s-hexadecyl coenzyme a - p21 space group Phyre2 PDB 5knk chain B Region: 23 - 258 Aligned: 210 Modelled: 222 Confidence: 99.6% Identity: 12% PDB header:transferase Chain: B: PDB Molecule:lipid a biosynthesis lauroyl acyltransferase; PDBTitle: lipid a secondary acyltransferase lpxm from acinetobacter baumannii2 with catalytic residue substitution (e127a) Phyre2 PDB 1iuq chain A Region: 29 - 208 Aligned: 175 Modelled: 180 Confidence: 99.2% Identity: 17% Fold: Glycerol-3-phosphate (1)-acyltransferase Superfamily: Glycerol-3-phosphate (1)-acyltransferase Family: Glycerol-3-phosphate (1)-acyltransferase Phyre2 PDB 4mxn chain B Region: 84 - 120 Aligned: 37 Modelled: 35 Confidence: 37.1% Identity: 11% PDB header:hydrolase Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a putative glycosyl hydrolase (parmer_00599) from2 parabacteroides merdae atcc 43184 at 1.95 a resolution Phyre2 PDB 4cyy chain A Region: 97 - 146 Aligned: 50 Modelled: 50 Confidence: 25.6% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:pantetheinase; PDBTitle: the structure of vanin-1: defining the link between metabolic disease,2 oxidative stress and inflammation Phyre2 PDB 3hkx chain A Region: 97 - 146 Aligned: 50 Modelled: 50 Confidence: 18.6% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:amidase; PDBTitle: crystal structure analysis of an amidase from nesterenkonia sp. Phyre2 PDB 2e11 chain B Region: 92 - 146 Aligned: 55 Modelled: 55 Confidence: 18.2% Identity: 20% PDB header:hydrolase Chain: B: PDB Molecule:hydrolase; PDBTitle: the crystal structure of xc1258 from xanthomonas campestris: a cn-2 hydrolase superfamily protein with an arsenic adduct in the active3 site Phyre2 PDB 5vrh chain A Region: 98 - 146 Aligned: 49 Modelled: 49 Confidence: 15.2% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:apolipoprotein n-acyltransferase; PDBTitle: apolipoprotein n-acyltransferase c387s active site mutant Phyre2 PDB 3jur chain A Region: 84 - 120 Aligned: 37 Modelled: 37 Confidence: 14.7% Identity: 27% PDB header:hydrolase Chain: A: PDB Molecule:exo-poly-alpha-d-galacturonosidase; PDBTitle: the crystal structure of a hyperthermoactive exopolygalacturonase from2 thermotoga maritima Phyre2 PDB 3zpp chain A Region: 84 - 120 Aligned: 37 Modelled: 37 Confidence: 14.1% Identity: 16% PDB header:cell adhesion Chain: A: PDB Molecule:cell wall surface anchor family protein; PDBTitle: structure of the streptococcus pneumoniae surface protein2 and adhesin pfba Phyre2 PDB 5olp chain B Region: 84 - 120 Aligned: 37 Modelled: 37 Confidence: 12.7% Identity: 24% PDB header:hydrolase Chain: B: PDB Molecule:pectate lyase; PDBTitle: galacturonidase Phyre2 PDB 5kha chain A Region: 97 - 146 Aligned: 50 Modelled: 50 Confidence: 12.1% Identity: 16% PDB header:ligase Chain: A: PDB Molecule:glutamine-dependent nad+ synthetase; PDBTitle: structure of glutamine-dependent nad+ synthetase from acinetobacter2 baumannii in complex with adenosine diphosphate (adp) Phyre2 PDB 3eqn chain B Region: 84 - 120 Aligned: 37 Modelled: 37 Confidence: 9.7% Identity: 16% PDB header:hydrolase Chain: B: PDB Molecule:glucan 1,3-beta-glucosidase; PDBTitle: crystal structure of beta-1,3-glucanase from phanerochaete2 chrysosporium (lam55a) Phyre2 PDB 2pyh chain B Region: 84 - 120 Aligned: 37 Modelled: 37 Confidence: 8.0% Identity: 22% PDB header:isomerase Chain: B: PDB Molecule:poly(beta-d-mannuronate) c5 epimerase 4; PDBTitle: azotobacter vinelandii mannuronan c-5 epimerase alge4 a-module2 complexed with mannuronan trisaccharide Phyre2 PDB 1v7z chain A Region: 101 - 154 Aligned: 54 Modelled: 54 Confidence: 6.9% Identity: 17% Fold: Creatininase Superfamily: Creatininase Family: Creatininase Phyre2 PDB 1ems chain B Region: 97 - 147 Aligned: 51 Modelled: 51 Confidence: 6.9% Identity: 14% PDB header:antitumor protein Chain: B: PDB Molecule:nit-fragile histidine triad fusion protein; PDBTitle: crystal structure of the c. elegans nitfhit protein Phyre2 PDB 1bhe chain A Region: 88 - 120 Aligned: 32 Modelled: 33 Confidence: 6.8% Identity: 13% Fold: Single-stranded right-handed beta-helix Superfamily: Pectin lyase-like Family: Galacturonase Phyre2 PDB 1hru chain A Region: 97 - 120 Aligned: 23 Modelled: 24 Confidence: 6.8% Identity: 26% Fold: YrdC/RibB Superfamily: YrdC/RibB Family: YrdC-like Phyre2 PDB 2csu chain A domain 1 Region: 95 - 146 Aligned: 52 Modelled: 51 Confidence: 6.4% Identity: 15% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: CoA-binding domain Phyre2 1 c5kymA_ 2 c5f34A_ 3 c5knkB_ 4 d1iuqa_ 5 c4mxnB_ 6 c4cyyA_ 7 c3hkxA_ 8 c2e11B_ 9 c5vrhA_ 10 c3jurA_ 11 c3zppA_ 12 c5olpB_ 13 c5khaA_ 14 c3eqnB_ 15 c2pyhB_ 16 d1v7za_ 17 c1emsB_ 18 d1bhea_ 19 d1hrua_ 20 d2csua1 21 22 23 24 25 26