1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	C	P	G	V	S	D	C	V	A	T	V	R	H	D	N	V	F	A	I	A	A	G	L	R	W	S	A	A	V	P	P	L	H	K	G	D	A	V	T	K	L	L	V	G	A	I	A	G	G	M	L	A	C	A	A	I	L	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?													?			?	?													?				?																			?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	G	I	A	S	A	D	T	A	L	I	V	P	G	T	A	P	S	P	Y	G	P	L	R	S	L	Y	H	F	N	P	A	M	Q	P	Q	I	G	A	N	Y	Y	N	P	T	A	T	R	H	V	V	S	Y	P	G	S	F	W	P	V
Secondary structure
SS confidence
Disorder		?	?	?																	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	G	L	N	S	P	T	V	G	S	S	V	S	A	G	T	N	N	L	D	A	A	I	R	S	T	D	G	P	I	F	V	A	G	L	S	Q	G	T	L	V	L	D	R	E	Q	A	R	L	A	N	D	P	T	A	P	P	P	G	Q
Secondary structure
SS confidence
Disorder																																																					?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	T	F	I	K	A	G	D	P	N	N	L	L	W	R	A	F	R	P	G	T	H	V	P	I	I	D	Y	T	V	P	A	P	A	E	S	Q	Y	D	T	I	N	I	V	G	Q	Y	D	I	F	S	D	P	P	N	R	P	G	N	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	A	D	L	N	A	I	A	A	G	G	Y	Y	G	H	S	A	T	A	F	S	D	P	A	R	V	A	P	R	D	I	T	T	T	T	N	S	L	G	A	T	T	T	T	Y	F	I	R	T	D	Q	L	P	L	V	R	A	L	V	D
Secondary structure
SS confidence
Disorder																											?	?	?	?	?						?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		M	A	G	L	P	P	Q	A	A	G	T	V	D	A	A	L	R	P	I	I	D	R	A	Y	Q	P	G	P	A	P	A	V	N	P	R	D	L	V	Q	G	I	R	G	I	P	A	I	A	P	A	I	A	I	P	I	G	S	T	T	G
Secondary structure
SS confidence
Disorder			?																																						?	?	?	?	?		?		?	?	?	?								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.
Sequence		A	S	A	A	T	S	T	A	A	A	T	A	A	A	T	N	A	L	R	G	A	N	V	G	P	G	A	N	K	A	L	S	M	V	R	G	L	L	P	K	G	K	K	H
Secondary structure
SS confidence
Disorder			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?							?		?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 21%) Alpha helix ( 36%) Beta strand ( 11%) TM helix ( 6%) (View membrane topology prediction)

Rank Aligned region

PDB 3aja chain A Region: 68 - 262 Aligned: 195 Modelled: 195 Confidence: 99.9% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of msmeg_6394 Phyre2 PDB 3hc7 chain A Region: 68 - 235 Aligned: 152 Modelled: 168 Confidence: 99.3% Identity: 18% PDB header:cell adhesion Chain: A: PDB Molecule:gene 12 protein; PDBTitle: crystal structure of lysin b from mycobacteriophage d29 Phyre2 PDB 1g66 chain A Region: 68 - 191 Aligned: 115 Modelled: 124 Confidence: 99.2% Identity: 23% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 1qoz chain A Region: 103 - 237 Aligned: 134 Modelled: 135 Confidence: 99.2% Identity: 23% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 2czq chain B Region: 68 - 239 Aligned: 152 Modelled: 172 Confidence: 99.0% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:cutinase-like protein; PDBTitle: a novel cutinase-like protein from cryptococcus sp. Phyre2 PDB 1cex chain A Region: 68 - 202 Aligned: 123 Modelled: 135 Confidence: 98.9% Identity: 14% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 3dd5 chain F Region: 68 - 202 Aligned: 124 Modelled: 135 Confidence: 98.9% Identity: 18% PDB header:hydrolase Chain: F: PDB Molecule:cutinase; PDBTitle: glomerella cingulata e600-cutinase complex Phyre2 PDB 5x88 chain A Region: 68 - 202 Aligned: 124 Modelled: 135 Confidence: 98.9% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:cutinase; PDBTitle: a crystal structure of cutinases from malbranchea cinnamomea Phyre2 PDB 3gbs chain A Region: 68 - 202 Aligned: 124 Modelled: 135 Confidence: 98.9% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:cutinase 1; PDBTitle: crystal structure of aspergillus oryzae cutinase Phyre2 PDB 4psd chain A Region: 109 - 192 Aligned: 73 Modelled: 84 Confidence: 98.7% Identity: 25% PDB header:hydrolase Chain: A: PDB Molecule:carbohydrate esterase family 5; PDBTitle: structure of trichoderma reesei cutinase native form. Phyre2 PDB 4oyl chain C Region: 68 - 202 Aligned: 121 Modelled: 131 Confidence: 98.5% Identity: 15% PDB header:hydrolase Chain: C: PDB Molecule:cutinase; PDBTitle: humicola insolens cutinase in complex with mono-ethylphosphate Phyre2 PDB 3icv chain A Region: 69 - 230 Aligned: 139 Modelled: 147 Confidence: 97.2% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:lipase b; PDBTitle: structural consequences of a circular permutation on lipase b from2 candida antartica Phyre2 PDB 1tca chain A Region: 69 - 230 Aligned: 139 Modelled: 154 Confidence: 96.9% Identity: 17% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Fungal lipases Phyre2 PDB 3ds8 chain A Region: 131 - 192 Aligned: 60 Modelled: 62 Confidence: 95.6% Identity: 27% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lin2722 protein; PDBTitle: the crysatl structure of the gene lin2722 products from listeria2 innocua Phyre2 PDB 5xav chain B Region: 105 - 189 Aligned: 79 Modelled: 85 Confidence: 95.5% Identity: 13% PDB header:biosynthetic protein Chain: B: PDB Molecule:intracellular polyhydroxyalkanoate synthase; PDBTitle: structure of phac from chromobacterium sp. usm2 Phyre2 PDB 5t6o chain A Region: 124 - 189 Aligned: 63 Modelled: 66 Confidence: 94.9% Identity: 21% PDB header:biosynthetic protein Chain: A: PDB Molecule:poly-beta-hydroxybuterate polymerase; PDBTitle: structure of the catalytic domain of the class i polyhydroxybutyrate2 synthase from cupriavidus necator Phyre2 PDB 6e6u chain A Region: 64 - 184 Aligned: 98 Modelled: 121 Confidence: 94.3% Identity: 17% PDB header:biosynthetic protein Chain: A: PDB Molecule:dieckmann cyclase, ncmc; PDBTitle: variant c89s of dieckmann cyclase, ncmc Phyre2 PDB 1ei9 chain A Region: 128 - 195 Aligned: 62 Modelled: 68 Confidence: 93.5% Identity: 18% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Thioesterases Phyre2 PDB 1jmk chain C Region: 118 - 190 Aligned: 66 Modelled: 73 Confidence: 93.4% Identity: 12% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Thioesterase domain of polypeptide, polyketide and fatty acid synthases Phyre2 PDB 3lp5 chain A Region: 124 - 247 Aligned: 122 Modelled: 124 Confidence: 91.9% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:putative cell surface hydrolase; PDBTitle: the crystal structure of the putative cell surface hydrolase from2 lactobacillus plantarum wcfs1 Phyre2 1 c3ajaA_ 2 c3hc7A_ 3 d1g66a_ 4 d1qoza_ 5 c2czqB_ 6 d1cexa_ 7 c3dd5F_ 8 c5x88A_ 9 c3gbsA_ 10 c4psdA_ 11 c4oylC_ 12 c3icvA_ 13 d1tcaa_ 14 c3ds8A_ 15 c5xavB_ 16 c5t6oA_ 17 c6e6uA_ 18 d1ei9a_ 19 d1jmkc_ 20 c3lp5A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122