Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD3823c_(mmpL8)_4288438_4291707
DateFri Aug 9 18:20:53 BST 2019
Unique Job ID101488b9319a0c5f
SequenceMCDVLMQPVR ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:65.563 Y:90.785 Z:114.961
Model (left) based on template c6ajjA_
Top template information
PDB header:membrane protein, hydrolase
Chain: A: PDB Molecule:drug exporters of the rnd superfamily-like protein,
PDBTitle: crystal structure of mycolic acid transporter mmpl3 from mycobacterium2 smegmatis complexed with ica38
Confidence and coverage
Confidence:100.0% Coverage: 66%
723 residues ( 66% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
1039 residues ( 95%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
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Sequence analysis 

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Secondary structure and disorder prediction [Show] 

Domain analysis [Show] 

Detailed template information [Hide] 

 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c6ajjA_
100.0 23
PDB header:membrane protein, hydrolase
Chain: A: PDB Molecule:drug exporters of the rnd superfamily-like protein,
PDBTitle: crystal structure of mycolic acid transporter mmpl3 from mycobacterium2 smegmatis complexed with ica38
2c5lq3F_
100.0 14
PDB header:transport protein
Chain: F: PDB Molecule:cmeb;
PDBTitle: structures and transport dynamics of the campylobacter jejuni2 multidrug efflux pump cmeb
3c3k07A_
100.0 16
PDB header:transport protein
Chain: A: PDB Molecule:cation efflux system protein cusa;
PDBTitle: crystal structure of cusa
4c4mt1A_
100.0 16
PDB header:membrane protein, tranport protein
Chain: A: PDB Molecule:drug efflux protein;
PDBTitle: crystal structure of the neisseria gonorrhoeae mtrd inner membrane2 multidrug efflux pump
5c6owsB_
100.0 14
PDB header:membrane protein
Chain: B: PDB Molecule:efflux pump membrane transporter;
PDBTitle: cryo-em structure of an acinetobacter baumannii multidrug efflux pump
6c2v50A_
100.0 13
PDB header:membrane protein
Chain: A: PDB Molecule:multidrug resistance protein mexb;
PDBTitle: the missing part of the bacterial mexab-oprm system: structural2 determination of the multidrug exporter mexb
7c4k0eA_
100.0 14
PDB header:transport protein
Chain: A: PDB Molecule:heavy metal cation tricomponent efflux pump znea(czca-
PDBTitle: x-ray crystal structure of a heavy metal efflux pump, crystal form ii
8c1oy8A_
100.0 14
PDB header:membrane protein
Chain: A: PDB Molecule:acriflavine resistance protein b;
PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump
9c5khnB_
100.0 18
PDB header:membrane protein
Chain: B: PDB Molecule:rnd transporter;
PDBTitle: crystal structures of the burkholderia multivorans hopanoid2 transporter hpnn
10c6dmoA_
100.0 13
PDB header:protein binding
Chain: A: PDB Molecule:protein patched homolog 1;
PDBTitle: cryo-em structure of human ptch1 with three mutations2 l282q/t500f/p504l
11c4k0eC_
100.0 15
PDB header:transport protein
Chain: C: PDB Molecule:heavy metal cation tricomponent efflux pump znea(czca-
PDBTitle: x-ray crystal structure of a heavy metal efflux pump, crystal form ii
12c6csxA_
100.0 14
PDB header:transport protein
Chain: A: PDB Molecule:multidrug efflux pump subunit acrb;
PDBTitle: single particles cryo-em structure of acrb d407a associated with lipid2 bilayer at 3.0 angstrom
13c3jd8A_
100.0 18
PDB header:membrane protein
Chain: A: PDB Molecule:niemann-pick c1 protein;
PDBTitle: cryo-em structure of the full-length human npc1 at 4.4 angstrom
14c3aqpB_
100.0 18
PDB header:membrane protein
Chain: B: PDB Molecule:probable secdf protein-export membrane protein;
PDBTitle: crystal structure of secdf, a translocon-associated membrane protein,2 from thermus thrmophilus
15c5xamA_
100.0 17
PDB header:membrane protein
Chain: A: PDB Molecule:protein translocase subunit secd;
PDBTitle: crystal structure of secdf in i form at 4 a resolution
16c5mg3D_
100.0 16
PDB header:chaperone
Chain: D: PDB Molecule:protein translocase subunit secd;
PDBTitle: em fitted model of bacterial holo-translocon
17d1iwga8
99.9 16
Fold:Multidrug efflux transporter AcrB transmembrane domain
Superfamily:Multidrug efflux transporter AcrB transmembrane domain
Family:Multidrug efflux transporter AcrB transmembrane domain
18c5mg3F_
99.9 12
PDB header:chaperone
Chain: F: PDB Molecule:protein translocase subunit secf;
PDBTitle: em fitted model of bacterial holo-translocon
19d1iwga7
99.9 16
Fold:Multidrug efflux transporter AcrB transmembrane domain
Superfamily:Multidrug efflux transporter AcrB transmembrane domain
Family:Multidrug efflux transporter AcrB transmembrane domain
20c5ensA_
99.2 10
PDB header:transport protein
Chain: A: PDB Molecule:multidrug efflux pump subunit acrb,multidrug efflux pump
PDBTitle: rhodamine bound structure of bacterial efflux pump.
21c4r86B_
not modelled 98.1 10
PDB header:protein transport
Chain: B: PDB Molecule:rnd family aminoglycoside/multidrug efflux pump;
PDBTitle: crystal structure of aminoglycoside/multidrug efflux system acrd from2 salmonella typhimurium
22d1iwga3
not modelled 81.3 8
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
23c2yvxD_
not modelled 73.7 14
PDB header:transport protein
Chain: D: PDB Molecule:mg2+ transporter mgte;
PDBTitle: crystal structure of magnesium transporter mgte
24d1iwga6
not modelled 62.7 6
Fold:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
25d1iwga2
not modelled 48.9 16
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
26d1iwga4
not modelled 47.6 20
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
27c5sxpG_
not modelled 46.3 47
PDB header:signaling protein/ligase
Chain: G: PDB Molecule:e3 ubiquitin-protein ligase itchy homolog;
PDBTitle: structural basis for the interaction between itch prr and beta-pix
28c4av3A_
not modelled 46.2 23
PDB header:hydrolase
Chain: A: PDB Molecule:k(+)-stimulated pyrophosphate-energized sodium pump;
PDBTitle: crystal structure of thermotoga maritima sodium pumping membrane2 integral pyrophosphatase with metal ions in active site
29c4b03D_
not modelled 27.8 20
PDB header:virus
Chain: D: PDB Molecule:dengue virus 1 prm protein;
PDBTitle: 6a electron cryomicroscopy structure of immature dengue virus serotype2 1
30c6n52B_
not modelled 26.3 14
PDB header:membrane protein
Chain: B: PDB Molecule:metabotropic glutamate receptor 5;
PDBTitle: metabotropic glutamate receptor 5 apo form
31c2mk9A_
not modelled 25.9 4
PDB header:immune system
Chain: A: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the dimeric transmembrane domain of toll-like2 receptor 3
32c2mkaB_
not modelled 25.9 4
PDB header:immune system
Chain: B: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the toll-like receptor 3 transmembrane domain in2 the trimeric state
33c2mkaA_
not modelled 25.9 4
PDB header:immune system
Chain: A: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the toll-like receptor 3 transmembrane domain in2 the trimeric state
34c2mkaC_
not modelled 25.9 4
PDB header:immune system
Chain: C: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the toll-like receptor 3 transmembrane domain in2 the trimeric state
35c2mk9B_
not modelled 25.9 4
PDB header:immune system
Chain: B: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the dimeric transmembrane domain of toll-like2 receptor 3
36c4a2nB_
not modelled 22.8 7
PDB header:transferase
Chain: B: PDB Molecule:isoprenylcysteine carboxyl methyltransferase;
PDBTitle: crystal structure of ma-icmt
37c5sxpF_
not modelled 22.7 50
PDB header:signaling protein/ligase
Chain: F: PDB Molecule:e3 ubiquitin-protein ligase itchy homolog;
PDBTitle: structural basis for the interaction between itch prr and beta-pix
38c1p58E_
not modelled 19.1 24
PDB header:virus
Chain: E: PDB Molecule:envelope protein m;
PDBTitle: complex organization of dengue virus membrane proteins as revealed by2 9.5 angstrom cryo-em reconstruction
39c1p58F_
not modelled 19.1 24
PDB header:virus
Chain: F: PDB Molecule:envelope protein m;
PDBTitle: complex organization of dengue virus membrane proteins as revealed by2 9.5 angstrom cryo-em reconstruction
40c1a87A_
not modelled 18.6 20
PDB header:bacteriocin
Chain: A: PDB Molecule:colicin n;
PDBTitle: colicin n
41d1a87a_
not modelled 18.6 20
Fold:Toxins' membrane translocation domains
Superfamily:Colicin
Family:Colicin
42c5zlgA_
not modelled 16.9 9
PDB header:oxidoreductase
Chain: A: PDB Molecule:cytochrome b reductase 1;
PDBTitle: human duodenal cytochrome b (dcytb) in zinc ion and ascorbate bound2 form
43c2bbjB_
not modelled 15.5 8
PDB header:metal transport/membrane protein
Chain: B: PDB Molecule:divalent cation transport-related protein;
PDBTitle: crystal structure of the cora mg2+ transporter
44c2m67A_
not modelled 14.6 14
PDB header:transport protein
Chain: A: PDB Molecule:merf;
PDBTitle: full-length mercury transporter protein merf in lipid bilayer2 membranes
45d2yvxa3
not modelled 14.5 14
Fold:MgtE membrane domain-like
Superfamily:MgtE membrane domain-like
Family:MgtE membrane domain-like
46c1ciiA_
not modelled 13.8 16
PDB header:transmembrane protein
Chain: A: PDB Molecule:colicin ia;
PDBTitle: colicin ia
47c3chxF_
not modelled 13.5 21
PDB header:membrane protein
Chain: F: PDB Molecule:pmoa;
PDBTitle: crystal structure of methylosinus trichosporium ob3b particulate2 methane monooxygenase (pmmo)
48c1rijA_
not modelled 13.3 55
PDB header:de novo protein
Chain: A: PDB Molecule:e6apn1 peptide;
PDBTitle: e6-bind trp-cage (e6apn1)
49c4or2A_
not modelled 12.3 13
PDB header:signaling protein
Chain: A: PDB Molecule:soluble cytochrome b562, metabotropic glutamate receptor 1;
PDBTitle: human class c g protein-coupled metabotropic glutamate receptor 1 in2 complex with a negative allosteric modulator
50c1qu7A_
not modelled 11.4 12
PDB header:signaling protein
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein i;
PDBTitle: four helical-bundle structure of the cytoplasmic domain of a serine2 chemotaxis receptor
51c4kppA_
not modelled 11.3 7
PDB header:membrane protein
Chain: A: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of h+/ca2+ exchanger cax
52c6o7ua_
not modelled 11.2 13
PDB header:membrane protein
Chain: A: PDB Molecule:
PDBTitle: saccharomyces cerevisiae v-atpase stv1-vo
53c2lj2A_
not modelled 11.2 12
PDB header:membrane protein
Chain: A: PDB Molecule:merf;
PDBTitle: integral membrane core domain of the mercury transporter merf in lipid2 bilayer membranes
54c1yewF_
not modelled 11.1 13
PDB header:oxidoreductase, membrane protein
Chain: F: PDB Molecule:particulate methane monooxygenase, a subunit;
PDBTitle: crystal structure of particulate methane monooxygenase
55c2kseA_
not modelled 11.1 20
PDB header:transferase
Chain: A: PDB Molecule:sensor protein qsec;
PDBTitle: backbone structure of the membrane domain of e. coli histidine kinase2 receptor qsec, center for structures of membrane proteins (csmp)3 target 4311c
56d1jb0i_
not modelled 10.9 16
Fold:Single transmembrane helix
Superfamily:Subunit VIII of photosystem I reaction centre, PsaI
Family:Subunit VIII of photosystem I reaction centre, PsaI
57c4fe1I_
not modelled 10.9 16
PDB header:photosynthesis
Chain: I: PDB Molecule:photosystem i reaction center subunit viii;
PDBTitle: improving the accuracy of macromolecular structure refinement at 7 a2 resolution
58c3ex7I_
not modelled 10.9 55
PDB header:hydrolase/rna binding protein/rna
Chain: I: PDB Molecule:protein casc3;
PDBTitle: the crystal structure of ejc in its transition state
59c5lnka_
not modelled 10.8 25
PDB header:oxidoreductase
Chain: A: PDB Molecule:mitochondrial complex i, nd3 subunit;
PDBTitle: entire ovine respiratory complex i
60c3j2pD_
not modelled 10.4 23
PDB header:viral protein
Chain: D: PDB Molecule:small envelope protein m;
PDBTitle: cryoem structure of dengue virus envelope protein heterotetramer
61d1sd4a_
not modelled 10.0 7
Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Penicillinase repressor
62c2ch7A_
not modelled 9.9 14
PDB header:chemotaxis
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein;
PDBTitle: crystal structure of the cytoplasmic domain of a bacterial2 chemoreceptor from thermotoga maritima
63c3n4dF_
not modelled 9.8 8
PDB header:hydrolase
Chain: F: PDB Molecule:putative tautomerase;
PDBTitle: crystal structure of cg10062 inactivated by(r)-oxirane-2-carboxylate
64c2k1aA_
not modelled 9.7 23
PDB header:cell adhesion
Chain: A: PDB Molecule:integrin alpha-iib;
PDBTitle: bicelle-embedded integrin alpha(iib) transmembrane segment
65c3javD_
not modelled 9.5 16
PDB header:transport protein
Chain: D: PDB Molecule:inositol 1,4,5-trisphosphate receptor type 1;
PDBTitle: structure of full-length ip3r1 channel in the apo-state determined by2 single particle cryo-em
66c5lpcA_
not modelled 9.4 20
PDB header:oxidoreductase
Chain: A: PDB Molecule:vanadium-dependent bromoperoxidase;
PDBTitle: crystal structure of vanadium-dependent haloperoxidase from a. marina
67c4p6vE_
not modelled 9.4 10
PDB header:oxidoreductase
Chain: E: PDB Molecule:na(+)-translocating nadh-quinone reductase subunit e;
PDBTitle: crystal structure of the na+-translocating nadh: ubiquinone2 oxidoreductase from vibrio cholerae
68c3j20P_
not modelled 9.2 9
PDB header:ribosome
Chain: P: PDB Molecule:30s ribosomal protein s14p type z;
PDBTitle: promiscuous behavior of proteins in archaeal ribosomes revealed by2 cryo-em: implications for evolution of eukaryotic ribosomes (30s3 ribosomal subunit)
69c2lugA_
not modelled 9.2 56
PDB header:lipid binding protein
Chain: A: PDB Molecule:myelin basic protein;
PDBTitle: solution nmr structure of a s72-s107 peptide of 18.5kda murine myelin2 basic protein (mbp) in association with dodecylphosphocholine3 micelles
70c5ws4A_
not modelled 9.1 12
PDB header:membrane protein
Chain: A: PDB Molecule:macrolide export atp-binding/permease protein macb;
PDBTitle: crystal structure of tripartite-type abc transporter macb from2 acinetobacter baumannii
71c5n9yB_
not modelled 9.0 13
PDB header:membrane protein
Chain: B: PDB Molecule:zinc transport protein zntb;
PDBTitle: the full-length structure of zntb
72c1fv1C_
not modelled 8.8 63
PDB header:immune system
Chain: C: PDB Molecule:myelin basic protein;
PDBTitle: structural basis for the binding of an immunodominant peptide from2 myelin basic protein in different registers by two hla-dr2 alleles
73c6f0kA_
not modelled 8.7 28
PDB header:membrane protein
Chain: A: PDB Molecule:cytochrome c family protein;
PDBTitle: alternative complex iii
74c2kncA_
not modelled 8.7 21
PDB header:cell adhesion
Chain: A: PDB Molecule:integrin alpha-iib;
PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex
75c6bqiA_
not modelled 8.4 10
PDB header:translation
Chain: A: PDB Molecule:protein impact homolog;
PDBTitle: structure of two-domain translational regulator yih1 reveals a2 possible mechanism of action
76c4gn0D_
not modelled 8.3 13
PDB header:signaling protein
Chain: D: PDB Molecule:hamp domain of af1503;
PDBTitle: de novo phasing of a hamp-complex using an improved arcimboldo method
77d1kf6d_
not modelled 8.3 8
Fold:Heme-binding four-helical bundle
Superfamily:Fumarate reductase respiratory complex transmembrane subunits
Family:Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD)
78c6hu9u_
not modelled 8.1 20
PDB header:oxidoreductase/electron transport
Chain: U: PDB Molecule:cytochrome b-c1 complex subunit 10;
PDBTitle: iii2-iv2 mitochondrial respiratory supercomplex from s. cerevisiae
79c3vepC_
not modelled 7.9 50
PDB header:membrane protein/transcription
Chain: C: PDB Molecule:uncharacterized protein rv3413c/mt3522;
PDBTitle: crystal structure of sigd4 in complex with its negative regulator rsda
80c5ireD_
not modelled 7.8 24
PDB header:virus
Chain: D: PDB Molecule:m protein;
PDBTitle: the cryo-em structure of zika virus
81c6mctE_
not modelled 7.8 33
PDB header:de novo protein
Chain: E: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
82c6mctA_
not modelled 7.8 33
PDB header:de novo protein
Chain: A: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
83c6mctN_
not modelled 7.8 33
PDB header:de novo protein
Chain: N: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
84c6mctB_
not modelled 7.8 33
PDB header:de novo protein
Chain: B: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
85c6mctG_
not modelled 7.8 33
PDB header:de novo protein
Chain: G: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
86c6mctH_
not modelled 7.8 33
PDB header:de novo protein
Chain: H: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
87c6mctJ_
not modelled 7.8 33
PDB header:de novo protein
Chain: J: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
88c6mctM_
not modelled 7.8 33
PDB header:de novo protein
Chain: M: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
89c6mctC_
not modelled 7.8 33
PDB header:de novo protein
Chain: C: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
90c6mctL_
not modelled 7.8 33
PDB header:de novo protein
Chain: L: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
91c6mctO_
not modelled 7.8 33
PDB header:de novo protein
Chain: O: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
92c6mpwA_
not modelled 7.8 33
PDB header:de novo protein
Chain: A: PDB Molecule:mini-evgl membrane protein;
PDBTitle: de novo design of membrane protein--mini-evgl membrane protein, c22212 form-1
93c6mctF_
not modelled 7.8 33
PDB header:de novo protein
Chain: F: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
94c6mctD_
not modelled 7.8 33
PDB header:de novo protein
Chain: D: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
95c6mq2D_
not modelled 7.8 33
PDB header:de novo protein
Chain: D: PDB Molecule:mini-evgl membrane protein;
PDBTitle: de novo design of membrane protein--mini-evgl membrane protein, c22212 form-2
96c6mctI_
not modelled 7.8 33
PDB header:de novo protein
Chain: I: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
97c6mctK_
not modelled 7.8 33
PDB header:de novo protein
Chain: K: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
98c6adqP_
not modelled 7.8 23
PDB header:electron transport
Chain: P: PDB Molecule:prokaryotic respiratory supercomplex associate factor 1
PDBTitle: respiratory complex ciii2civ2sod2 from mycobacterium smegmatis
99c3w66A_
not modelled 7.7 11
PDB header:metal transport
Chain: A: PDB Molecule:magnetosome protein mamm;
PDBTitle: mamm-ctd d249a and h285a

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Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below