1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	D	R	V	R	R	V	V	T	D	R	D	S	G	A	G	A	L	A	R	H	P	L	A	G	R	R	T	D	P	Q	L	A	A	F	Y	H	R	L	M	T	T	Q	R	H	C	H	T	Q	A	T	I	A	V	A	R	K	L	A	E
Secondary structure
SS confidence
Disorder		?	?	?	?		?	?					?	?	?	?	?	?	?		?		?		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.
Sequence		R	T	R	V	T	I	T	T	G	R	P	Y	Q	L	R	D	T	N	G	D	P	V	T	A	R	G	A	K	E	L	I	D	A	H	Y	H	V	D	T	R	T	H	P	H	N	R	A	H	T	D	T	M	Q	N	S	K	P	A	R
Secondary structure
SS confidence
Disorder																				?	?		?	?	?															?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 39%) Alpha helix ( 63%) Beta strand ( 4%)

Rank Aligned region

PDB 5ux1 chain D Region: 29 - 55 Aligned: 26 Modelled: 27 Confidence: 31.1% Identity: 27% PDB header:lyase Chain: D: PDB Molecule:trna-(ms(2)io(6)a)-hydroxylase-like; PDBTitle: protein 43 with aldehyde deformylating oxygenase activity from2 synechococcus Phyre2 PDB 2itb chain A domain 1 Region: 29 - 67 Aligned: 38 Modelled: 39 Confidence: 29.2% Identity: 24% Fold: Ferritin-like Superfamily: Ferritin-like Family: MiaE-like Phyre2 PDB 2wgh chain A Region: 55 - 74 Aligned: 20 Modelled: 20 Confidence: 23.0% Identity: 35% PDB header:oxidoreductase Chain: A: PDB Molecule:ribonucleoside-diphosphate reductase large PDBTitle: human ribonucleotide reductase r1 subunit (rrm1) in complex2 with datp and mg. Phyre2 PDB 4txo chain B Region: 69 - 86 Aligned: 18 Modelled: 18 Confidence: 18.3% Identity: 50% PDB header:oxidodreductase/copper binding protein Chain: B: PDB Molecule:blr1131 protein; PDBTitle: crystal structure of the mixed disulfide complex of thioredoxin-like2 tlpas(c110s) and copper chaperone scois(c74s) Phyre2 PDB 1xje chain A Region: 55 - 74 Aligned: 20 Modelled: 20 Confidence: 17.4% Identity: 20% PDB header:oxidoreductase Chain: A: PDB Molecule:ribonucleotide reductase, b12-dependent; PDBTitle: structural mechanism of allosteric substrate specificity in a2 ribonucleotide reductase: dttp-gdp complex Phyre2 PDB 1r5l chain A domain 2 Region: 62 - 82 Aligned: 21 Modelled: 21 Confidence: 17.1% Identity: 29% Fold: SpoIIaa-like Superfamily: CRAL/TRIO domain Family: CRAL/TRIO domain Phyre2 PDB 1peq chain A domain 2 Region: 55 - 74 Aligned: 20 Modelled: 20 Confidence: 16.0% Identity: 25% Fold: PFL-like glycyl radical enzymes Superfamily: PFL-like glycyl radical enzymes Family: R1 subunit of ribonucleotide reductase, C-terminal domain Phyre2 PDB 6cgm chain A Region: 55 - 74 Aligned: 20 Modelled: 20 Confidence: 15.9% Identity: 35% PDB header:oxidoreductase Chain: A: PDB Molecule:ribonucleoside-diphosphate reductase; PDBTitle: x-ray crystal structure of bacillus subtilis ribonucleotide reductase2 nrde alpha subunit (nucleotide free) Phyre2 PDB 2cuq chain A domain 1 Region: 68 - 81 Aligned: 12 Modelled: 12 Confidence: 15.4% Identity: 33% Fold: Glucocorticoid receptor-like (DNA-binding domain) Superfamily: Glucocorticoid receptor-like (DNA-binding domain) Family: LIM domain Phyre2 PDB 2cvu chain A Region: 55 - 74 Aligned: 20 Modelled: 20 Confidence: 15.0% Identity: 30% PDB header:oxidoreductase Chain: A: PDB Molecule:ribonucleoside-diphosphate reductase large chain PDBTitle: structures of yeast ribonucleotide reductase i Phyre2 PDB 3wl7 chain A Region: 68 - 93 Aligned: 25 Modelled: 26 Confidence: 14.4% Identity: 28% PDB header:hydrolase Chain: A: PDB Molecule:oxidized polyvinyl alcohol hydrolase; PDBTitle: the complex structure of poph s172c with ligand, aca Phyre2 PDB 2jph chain A Region: 66 - 97 Aligned: 32 Modelled: 32 Confidence: 12.8% Identity: 22% PDB header:signaling protein, protein binding Chain: A: PDB Molecule:plexin-b1; PDBTitle: nmr solution structure of the rho gtpase binding domain of2 human plexin-b1 Phyre2 PDB 6n5u chain C Region: 69 - 86 Aligned: 18 Modelled: 18 Confidence: 11.6% Identity: 33% PDB header:metal binding protein Chain: C: PDB Molecule:protein sco1 homolog 1, mitochondrial; PDBTitle: crystal structure of arabidopsis thaliana scoi with copper bound Phyre2 PDB 1pem chain A Region: 55 - 74 Aligned: 20 Modelled: 20 Confidence: 11.1% Identity: 25% PDB header:oxidoreductase Chain: A: PDB Molecule:ribonucleoside-diphosphate reductase 2 alpha PDBTitle: ribonucleotide reductase protein r1e from salmonella2 typhimurium Phyre2 PDB 6dqw chain D Region: 55 - 74 Aligned: 20 Modelled: 20 Confidence: 10.8% Identity: 20% PDB header:oxidoreductase Chain: D: PDB Molecule:ribonucleoside-diphosphate reductase, alpha chain; PDBTitle: flavobacterium johnsoniae class id ribonucleotide reductase alpha2 subuint Phyre2 PDB 6dqx chain A Region: 55 - 74 Aligned: 20 Modelled: 20 Confidence: 10.7% Identity: 30% PDB header:oxidoreductase Chain: A: PDB Molecule:ribonucleoside-diphosphate reductase, alpha chain; PDBTitle: actinobacillus ureae class id ribonucleotide reductase alpha subunit Phyre2 PDB 1xou chain B Region: 27 - 42 Aligned: 16 Modelled: 16 Confidence: 10.1% Identity: 38% Fold: EspA/CesA-like Superfamily: EspA/CesA-like Family: EspA chaperone CesA Phyre2 PDB 3hnf chain A Region: 55 - 74 Aligned: 20 Modelled: 20 Confidence: 9.6% Identity: 35% PDB header:oxidoreductase Chain: A: PDB Molecule:ribonucleoside-diphosphate reductase large subunit; PDBTitle: crystal structure of human ribonucleotide reductase 1 bound to the2 effectors ttp and datp Phyre2 PDB 6fh4 chain D Region: 79 - 95 Aligned: 17 Modelled: 17 Confidence: 9.3% Identity: 6% PDB header:signaling protein Chain: D: PDB Molecule:transcriptional regulator ctsr; PDBTitle: ctsr c-terminal domain with bound phospho-arginine Phyre2 PDB 1cwv chain A domain 3 Region: 72 - 83 Aligned: 12 Modelled: 12 Confidence: 8.7% Identity: 25% Fold: Immunoglobulin-like beta-sandwich Superfamily: Invasin/intimin cell-adhesion fragments Family: Invasin/intimin cell-adhesion fragments Phyre2 1 c5ux1D_ 2 d2itba1 3 c2wghA_ 4 c4txoB_ 5 c1xjeA_ 6 d1r5la2 7 d1peqa2 8 c6cgmA_ 9 d2cuqa1 10 c2cvuA_ 11 c3wl7A_ 12 c2jphA_ 13 c6n5uC_ 14 c1pemA_ 15 c6dqwD_ 16 c6dqxA_ 17 d1xoub_ 18 c3hnfA_ 19 c6fh4D_ 20 d1cwva3 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46