1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	G	L	F	G	K	R	K	S	R	A	T	R	R	A	E	A	R	A	I	K	A	R	A	K	L	E	A	K	L	S	A	K	N	E	A	R	R	I	K	A	A	Q	R	A	E	S	K	A	L	K	A	Q	L	K	A	R	R	D	S
Secondary structure
SS confidence
Disorder		?	?	?	?				?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	R	A	A	L	K	V	A	E	A	E	L	K	V	A	R	E	G	K	L	L	S	P	T	R	I	R	R	L	L	T	V	S	R	L	L	A	P	I	L	T	P	V	I	Y	R	A	A	M	A	A	R	G	L	I	D	Q	R	R	A
Secondary structure
SS confidence
Disorder																		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		D	Q	L	G	V	P	L	A	Q	I	G	R	F	S	G	H	G	A	R	L	S	A	R	V	G	G	A	E	R	S	L	R	M	V	Q	E	K	K	P	K	D	V	E	T	K	Q	F	V	S	A	V	T	N	R	L	T	D	L	S	A
Secondary structure
SS confidence
Disorder				?	?	?	?					?	?	?	?	?	?		?	?																	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.
Sequence		A	V	A	A	A	E	H	M	P	A	K	R	R	R	T	A	H	S	A	I	S	S	Q	L	D	G	I	E	A	D	L	M	A	R	L	G	L	T
Secondary structure
SS confidence
Disorder								?	?	?																										?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 18%) Alpha helix ( 87%) Beta strand ( 0%)

Rank Aligned region

PDB 4dnd chain A Region: 171 - 211 Aligned: 41 Modelled: 40 Confidence: 71.1% Identity: 17% PDB header:transport protein Chain: A: PDB Molecule:syntaxin-10; PDBTitle: crystal structure of syntaxin 10 from homo sapiens Phyre2 PDB 5frg chain A Region: 186 - 213 Aligned: 25 Modelled: 28 Confidence: 68.8% Identity: 24% PDB header:protein binding Chain: A: PDB Molecule:formin-binding protein 1-like; PDBTitle: the nmr structure of the cdc42-interacting region of toca1 Phyre2 PDB 2ke4 chain A Region: 186 - 213 Aligned: 25 Modelled: 28 Confidence: 66.6% Identity: 24% PDB header:membrane protein Chain: A: PDB Molecule:cdc42-interacting protein 4; PDBTitle: the nmr structure of the tc10 and cdc42 interacting domain2 of cip4 Phyre2 PDB 1lvf chain A Region: 168 - 213 Aligned: 46 Modelled: 46 Confidence: 65.5% Identity: 17% Fold: STAT-like Superfamily: t-snare proteins Family: t-snare proteins Phyre2 PDB 1f4j chain C Region: 188 - 214 Aligned: 27 Modelled: 27 Confidence: 39.2% Identity: 11% PDB header:oxidoreductase Chain: C: PDB Molecule:catalase; PDBTitle: structure of tetragonal crystals of human erythrocyte catalase Phyre2 PDB 1szp chain A domain 1 Region: 65 - 99 Aligned: 35 Modelled: 35 Confidence: 36.3% Identity: 31% Fold: SAM domain-like Superfamily: Rad51 N-terminal domain-like Family: DNA repair protein Rad51, N-terminal domain Phyre2 PDB 4blc chain A Region: 188 - 214 Aligned: 27 Modelled: 27 Confidence: 34.5% Identity: 11% Fold: Heme-dependent catalase-like Superfamily: Heme-dependent catalase-like Family: Heme-dependent catalases Phyre2 PDB 4cab chain A Region: 187 - 214 Aligned: 28 Modelled: 28 Confidence: 34.3% Identity: 18% PDB header:oxidoreductase Chain: A: PDB Molecule:catalase; PDBTitle: the refined structure of catalase dr1998 from deinococcus radiodurans2 at 2.6 a resolution Phyre2 PDB 1e93 chain A Region: 186 - 214 Aligned: 29 Modelled: 29 Confidence: 31.7% Identity: 14% Fold: Heme-dependent catalase-like Superfamily: Heme-dependent catalase-like Family: Heme-dependent catalases Phyre2 PDB 1dgf chain A Region: 188 - 214 Aligned: 27 Modelled: 27 Confidence: 31.5% Identity: 11% Fold: Heme-dependent catalase-like Superfamily: Heme-dependent catalase-like Family: Heme-dependent catalases Phyre2 PDB 6fia chain B Region: 139 - 186 Aligned: 48 Modelled: 48 Confidence: 29.2% Identity: 27% PDB header:rna binding protein Chain: B: PDB Molecule:line-1 retrotransposable element orf1 protein; PDBTitle: structure of the human line-1 orf1p coiled coil domain Phyre2 PDB 1u9p chain A Region: 187 - 215 Aligned: 29 Modelled: 29 Confidence: 29.0% Identity: 7% PDB header:unknown function Chain: A: PDB Molecule:parc; PDBTitle: permuted single-chain arc Phyre2 PDB 1mnt chain A Region: 187 - 215 Aligned: 29 Modelled: 29 Confidence: 27.9% Identity: 14% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: Arc/Mnt-like phage repressors Phyre2 PDB 1m7s chain A Region: 186 - 214 Aligned: 29 Modelled: 29 Confidence: 27.9% Identity: 10% Fold: Heme-dependent catalase-like Superfamily: Heme-dependent catalase-like Family: Heme-dependent catalases Phyre2 PDB 3gei chain B Region: 126 - 215 Aligned: 85 Modelled: 90 Confidence: 27.0% Identity: 26% PDB header:hydrolase Chain: B: PDB Molecule:trna modification gtpase mnme; PDBTitle: crystal structure of mnme from chlorobium tepidum in complex2 with gcp Phyre2 PDB 1ye9 chain E Region: 186 - 214 Aligned: 29 Modelled: 29 Confidence: 26.6% Identity: 14% PDB header:oxidoreductase Chain: E: PDB Molecule:catalase hpii; PDBTitle: crystal structure of proteolytically truncated catalase2 hpii from e. coli Phyre2 PDB 1gwe chain A Region: 186 - 214 Aligned: 29 Modelled: 29 Confidence: 26.0% Identity: 24% Fold: Heme-dependent catalase-like Superfamily: Heme-dependent catalase-like Family: Heme-dependent catalases Phyre2 PDB 4qoq chain C Region: 187 - 214 Aligned: 28 Modelled: 28 Confidence: 24.7% Identity: 7% PDB header:oxidoreductase Chain: C: PDB Molecule:catalase; PDBTitle: structure of bacillus pumilus catalase with guaiacol bound Phyre2 PDB 6g18 chain T Region: 29 - 78 Aligned: 50 Modelled: 50 Confidence: 23.2% Identity: 24% PDB header:ribosome Chain: T: PDB Molecule:40s ribosomal protein s19; PDBTitle: cryo-em structure of a late human pre-40s ribosomal subunit - state c Phyre2 PDB 6g53 chain T Region: 29 - 78 Aligned: 50 Modelled: 50 Confidence: 23.1% Identity: 24% PDB header:ribosome Chain: T: PDB Molecule:40s ribosomal protein s19; PDBTitle: cryo-em structure of a late human pre-40s ribosomal subunit - state e Phyre2 1 c4dndA_ 2 c5frgA_ 3 c2ke4A_ 4 d1lvfa_ 5 c1f4jC_ 6 d1szpa1 7 d4blca_ 8 c4cabA_ 9 d1e93a_ 10 d1dgfa_ 11 c6fiaB_ 12 c1u9pA_ 13 d1mnta_ 14 d1m7sa_ 15 c3geiB_ 16 c1ye9E_ 17 d1gwea_ 18 c4qoqC_ 19 c6g18t_ 20 c6g53t_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85