1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	A	I	S	F	R	P	T	A	D	L	V	D	D	I	G	P	D	V	R	S	C	D	L	Q	F	R	Q	F	G	G	R	S	Q	F	A	G	P	I	S	T	V	R	C	F	Q	D	N	A	L	L	K	S	V	L	S	Q	P	S	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?													?									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	G	V	L	V	I	D	G	A	G	S	L	H	T	A	L	V	G	D	V	I	A	E	L	A	R	S	T	G	W	T	G	L	I	V	H	G	A	V	R	D	A	A	A	L	R	G	I	D	I	G	I	K	A	L	G	T	N	P	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.
Sequence		K	S	T	K	T	G	A	G	E	R	D	V	E	I	T	L	G	G	V	T	F	V	P	G	D	I	A	Y	S	D	D	D	G	I	I	V	V
Secondary structure
SS confidence
Disorder																																						?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 6%) Alpha helix ( 20%) Beta strand ( 37%)

Rank Aligned region

PDB 1nxj chain A Region: 2 - 157 Aligned: 156 Modelled: 156 Confidence: 100.0% Identity: 100% PDB header:unknown function Chain: A: PDB Molecule:probable s-adenosylmethionine:2- PDBTitle: structure of rv3853 from mycobacterium tuberculosis Phyre2 PDB 1nxj chain A Region: 2 - 157 Aligned: 156 Modelled: 156 Confidence: 100.0% Identity: 100% Fold: The "swivelling" beta/beta/alpha domain Superfamily: RraA-like Family: RraA-like Phyre2 PDB 2pcn chain A Region: 6 - 157 Aligned: 152 Modelled: 152 Confidence: 100.0% Identity: 44% PDB header:transferase Chain: A: PDB Molecule:s-adenosylmethionine:2-demethylmenaquinone PDBTitle: crystal structure of s-adenosylmethionine: 2-dimethylmenaquinone2 methyltransferase (gk_1813) from geobacillus kaustophilus hta426 Phyre2 PDB 1vi4 chain A Region: 8 - 157 Aligned: 150 Modelled: 148 Confidence: 100.0% Identity: 47% Fold: The "swivelling" beta/beta/alpha domain Superfamily: RraA-like Family: RraA-like Phyre2 PDB 1q5x chain A Region: 6 - 157 Aligned: 152 Modelled: 152 Confidence: 100.0% Identity: 45% Fold: The "swivelling" beta/beta/alpha domain Superfamily: RraA-like Family: RraA-like Phyre2 PDB 3c8o chain B Region: 5 - 157 Aligned: 153 Modelled: 153 Confidence: 100.0% Identity: 44% PDB header:hydrolase regulator Chain: B: PDB Molecule:regulator of ribonuclease activity a; PDBTitle: the crystal structure of rraa from pao1 Phyre2 PDB 3noj chain A Region: 2 - 157 Aligned: 155 Modelled: 156 Confidence: 100.0% Identity: 27% PDB header:lyase Chain: A: PDB Molecule:4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate PDBTitle: the structure of hmg/cha aldolase from the protocatechuate degradation2 pathway of pseudomonas putida Phyre2 PDB 1j3l chain A Region: 6 - 157 Aligned: 151 Modelled: 152 Confidence: 100.0% Identity: 45% Fold: The "swivelling" beta/beta/alpha domain Superfamily: RraA-like Family: RraA-like Phyre2 PDB 5ir2 chain A Region: 2 - 157 Aligned: 156 Modelled: 154 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:cellulase; PDBTitle: crystal structure of novel cellulases from microbes associated with2 the gut ecosystem Phyre2 PDB 3k4i chain C Region: 2 - 157 Aligned: 155 Modelled: 155 Confidence: 100.0% Identity: 21% PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein pspto_3204 from2 pseudomonas syringae pv. tomato str. dc3000 Phyre2 PDB 5x15 chain C Region: 2 - 157 Aligned: 155 Modelled: 156 Confidence: 100.0% Identity: 28% PDB header:transferase inhibitor Chain: C: PDB Molecule:putative transferase; PDBTitle: crystal structure of streptomyces coelicolor rraas2, an unusual member2 of the rnase es inhibitor rraa protein family Phyre2 PDB 2c5q chain E Region: 2 - 157 Aligned: 156 Modelled: 156 Confidence: 100.0% Identity: 20% PDB header:structural genomics,unknown function Chain: E: PDB Molecule:rraa-like protein yer010c; PDBTitle: crystal structure of yeast yer010cp Phyre2 PDB 2gp4 chain A domain 1 Region: 33 - 98 Aligned: 63 Modelled: 66 Confidence: 72.3% Identity: 17% Fold: The "swivelling" beta/beta/alpha domain Superfamily: LeuD/IlvD-like Family: IlvD/EDD C-terminal domain-like Phyre2 PDB 2gp4 chain A Region: 33 - 98 Aligned: 63 Modelled: 66 Confidence: 70.7% Identity: 16% PDB header:lyase Chain: A: PDB Molecule:6-phosphogluconate dehydratase; PDBTitle: structure of [fes]cluster-free apo form of 6-phosphogluconate2 dehydratase from shewanella oneidensis Phyre2 PDB 2gp4 chain B Region: 33 - 98 Aligned: 63 Modelled: 66 Confidence: 66.8% Identity: 16% PDB header:lyase Chain: B: PDB Molecule:6-phosphogluconate dehydratase; PDBTitle: structure of [fes]cluster-free apo form of 6-phosphogluconate2 dehydratase from shewanella oneidensis Phyre2 PDB 6ovt chain D Region: 19 - 97 Aligned: 76 Modelled: 79 Confidence: 56.9% Identity: 18% PDB header:lyase Chain: D: PDB Molecule:dihydroxy-acid dehydratase; PDBTitle: crystal structure of ilvd from mycobacterium tuberculosis Phyre2 PDB 5j84 chain A Region: 33 - 98 Aligned: 63 Modelled: 65 Confidence: 55.7% Identity: 14% PDB header:lyase Chain: A: PDB Molecule:dihydroxy-acid dehydratase; PDBTitle: crystal structure of l-arabinonate dehydratase in holo-form Phyre2 PDB 5oyn chain B Region: 30 - 98 Aligned: 66 Modelled: 69 Confidence: 53.1% Identity: 20% PDB header:lyase Chain: B: PDB Molecule:dehydratase, ilvd/edd family; PDBTitle: crystal structure of d-xylonate dehydratase in holo-form Phyre2 PDB 1kbl chain A domain 2 Region: 53 - 156 Aligned: 88 Modelled: 104 Confidence: 48.9% Identity: 23% Fold: The "swivelling" beta/beta/alpha domain Superfamily: Phosphohistidine domain Family: Pyruvate phosphate dikinase, central domain Phyre2 PDB 5ze4 chain A Region: 33 - 97 Aligned: 62 Modelled: 65 Confidence: 48.4% Identity: 26% PDB header:lyase Chain: A: PDB Molecule:dihydroxy-acid dehydratase, chloroplastic; PDBTitle: the structure of holo- structure of dhad complex with [2fe-2s] cluster Phyre2 1 c1nxjA_ 2 d1nxja_ 3 c2pcnA_ 4 d1vi4a_ 5 d1q5xa_ 6 c3c8oB_ 7 c3nojA_ 8 d1j3la_ 9 c5ir2A_ 10 c3k4iC_ 11 c5x15C_ 12 c2c5qE_ 13 d2gp4a1 14 c2gp4A_ 15 c2gp4B_ 16 c6ovtD_ 17 c5j84A_ 18 c5oynB_ 19 d1kbla2 20 c5ze4A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81