Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD3879c_(-)_4357771_4359960
DateSat Aug 10 22:05:06 BST 2019
Unique Job IDb8773fd6f02dcd2d
SequenceMSITRPTGSY ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:21.879 Y:65.286 Z:21.000
Model (left) based on template c4iogD_
Top template information
PDB header:unknown function
Chain: D: PDB Molecule:secreted protein esxb;
PDBTitle: the crystal structure of a secreted protein esxb (wild-type, in p212 space group) from bacillus anthracis str. sterne
Confidence and coverage
Confidence: 96.8% Coverage: 11%
81 residues ( 11% of your sequence) have been modelled with 96.8% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
166 residues ( 23%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
Warning: 62% of your sequence is predicted disordered. Disordered regions cannot be meaningfully predicted.
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Sequence analysis 

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Secondary structure and disorder prediction [Show] 

Domain analysis [Show] 

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Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c4iogD_
96.8 11
PDB header:unknown function
Chain: D: PDB Molecule:secreted protein esxb;
PDBTitle: the crystal structure of a secreted protein esxb (wild-type, in p212 space group) from bacillus anthracis str. sterne
2c3gvmA_
96.8 21
PDB header:viral protein
Chain: A: PDB Molecule:putative uncharacterized protein sag1039;
PDBTitle: structure of the homodimeric wxg-100 family protein from streptococcus2 agalactiae
3c2vs0B_
96.7 12
PDB header:cell invasion
Chain: B: PDB Molecule:virulence factor esxa;
PDBTitle: structural analysis of homodimeric staphylococcal aureus2 virulence factor esxa
4c4lwsA_
96.7 13
PDB header:unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: esxa : esxb (semet) hetero-dimer from thermomonospora curvata
5c3zbhC_
96.6 16
PDB header:unknown function
Chain: C: PDB Molecule:esxa;
PDBTitle: geobacillus thermodenitrificans esxa crystal form i
6d1wa8a1
95.6 18
Fold:Ferritin-like
Superfamily:EsxAB dimer-like
Family:ESAT-6 like
7c4lwsB_
94.6 13
PDB header:unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: esxa : esxb (semet) hetero-dimer from thermomonospora curvata
8d1wa8b1
93.4 13
Fold:Ferritin-like
Superfamily:EsxAB dimer-like
Family:ESAT-6 like
9d2g38b1
91.0 14
Fold:Ferritin-like
Superfamily:PE/PPE dimer-like
Family:PPE
10c2g38B_
91.0 14
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:ppe family protein;
PDBTitle: a pe/ppe protein complex from mycobacterium tuberculosis
11c3f1iH_
87.5 14
PDB header:protein binding
Chain: H: PDB Molecule:hepatocyte growth factor-regulated tyrosine kinase
PDBTitle: human escrt-0 core complex
12c5imuA_
86.6 22
PDB header:signaling protein
Chain: A: PDB Molecule:tat (twin-arginine translocation) pathway signal sequence
PDBTitle: a fragment of conserved hypothetical protein rv3899c (residues 184-2 410) from mycobacterium tuberculosis
13c1ei3E_
84.7 12
PDB header:blood clotting
Chain: E: PDB Molecule:fibrinogen;
PDBTitle: crystal structure of native chicken fibrinogen
14c2p0pA_
80.6 47
PDB header:metal binding protein
Chain: A: PDB Molecule:alr1010 protein;
PDBTitle: calcium binding protein in the free form
15c1deqF_
79.8 9
PDB header:blood clotting
Chain: F: PDB Molecule:fibrinogen (gamma chain);
PDBTitle: the crystal structure of modified bovine fibrinogen (at ~42 angstrom resolution)
16c2kg7B_
79.7 6
PDB header:unknown function
Chain: B: PDB Molecule:esat-6-like protein esxh;
PDBTitle: structure and features of the complex formed by the tuberculosis2 virulence factors rv0287 and rv0288
17c1deqO_
72.3 10
PDB header:blood clotting
Chain: O: PDB Molecule:fibrinogen (beta chain);
PDBTitle: the crystal structure of modified bovine fibrinogen (at ~42 angstrom resolution)
18c6e2jB_
72.1 10
PDB header:protein fibril
Chain: B: PDB Molecule:keratin, type i cytoskeletal 10;
PDBTitle: crystal structure of the heterocomplex between human keratin 1 coil 1b2 containing s233l mutation and wild-type human keratin 10 coil 1b
19c2gl2B_
69.0 18
PDB header:cell adhesion
Chain: B: PDB Molecule:adhesion a;
PDBTitle: crystal structure of the tetra muntant (t66g,r67g,f68g,y69g) of2 bacterial adhesin fada
20c6ec0A_
67.3 8
PDB header:protein fibril
Chain: A: PDB Molecule:keratin 1;
PDBTitle: crystal structure of the wild-type heterocomplex between coil 1b2 domains of human intermediate filament proteins keratin 1 (krt1) and3 keratin 10 (krt10)
21c3ghgI_
not modelled 63.3 8
PDB header:blood clotting
Chain: I: PDB Molecule:fibrinogen gamma chain;
PDBTitle: crystal structure of human fibrinogen
22c5xfsB_
not modelled 61.2 12
PDB header:protein transport
Chain: B: PDB Molecule:ppe family protein ppe15;
PDBTitle: crystal structure of pe8-ppe15 in complex with espg5 from m.2 tuberculosis
23c1ei3C_
not modelled 60.4 13
PDB header:blood clotting
Chain: C: PDB Molecule:fibrinogen;
PDBTitle: crystal structure of native chicken fibrinogen
24c6a9pD_
not modelled 59.7 11
PDB header:structural protein
Chain: D: PDB Molecule:glial fibrillary acidic protein;
PDBTitle: crystal structure of the human glial fibrillary acidic protein 1b2 domain
25c3ojaB_
not modelled 59.1 10
PDB header:protein binding
Chain: B: PDB Molecule:anopheles plasmodium-responsive leucine-rich repeat protein
PDBTitle: crystal structure of lrim1/apl1c complex
26c4i0xA_
not modelled 59.0 13
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:esat-6-like protein mab_3112;
PDBTitle: crystal structure of the mycobacterum abscessus esxef (mab_3112-2 mab_3113) complex
27c3ghgK_
not modelled 58.9 10
PDB header:blood clotting
Chain: K: PDB Molecule:fibrinogen beta chain;
PDBTitle: crystal structure of human fibrinogen
28c3ol1A_
not modelled 57.6 11
PDB header:structural protein
Chain: A: PDB Molecule:vimentin;
PDBTitle: crystal structure of vimentin (fragment 144-251) from homo sapiens,2 northeast structural genomics consortium target hr4796b
29c5ew5C_
not modelled 49.7 7
PDB header:hydrolase
Chain: C: PDB Molecule:colicin-e9;
PDBTitle: crystal structure of colicin e9 in complex with its immunity protein2 im9
30c4l6rA_
not modelled 49.6 7
PDB header:membrane protein
Chain: A: PDB Molecule:soluble cytochrome b562 and glucagon receptor chimera;
PDBTitle: structure of the class b human glucagon g protein coupled receptor
31c4wj2A_
not modelled 48.9 12
PDB header:unknown function
Chain: A: PDB Molecule:antigen mtb48;
PDBTitle: mycobacterial protein
32c4pjuB_
not modelled 48.8 37
PDB header:cell cycle
Chain: B: PDB Molecule:double-strand-break repair protein rad21 homolog;
PDBTitle: crystal structure of human stromal antigen 2 (sa2) in complex with2 sister chromatid cohesion protein 1 (scc1)
33c4yiiA_
not modelled 47.7 36
PDB header:ligase/cell cycle
Chain: A: PDB Molecule:anaphase-promoting complex subunit 2;
PDBTitle: structure of an apc2-ubch10 complex reveals distinctive cullin-ring2 ligase mechanism for anaphase-promoting complex/cyclosome
34c6gajA_
not modelled 47.5 7
PDB header:viral protein
Chain: A: PDB Molecule:outer capsid protein sigma-1;
PDBTitle: crystal structure of the t1l reovirus sigma1 coiled coil tail (iodide)
35c3terA_
not modelled 45.6 5
PDB header:metal binding protein
Chain: A: PDB Molecule:mammalian stromal interaction molecule-1;
PDBTitle: crystal structure of soar domain with inhibition helix from c. elegans
36c3g67A_
not modelled 45.2 10
PDB header:signaling protein
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein;
PDBTitle: crystal structure of a soluble chemoreceptor from thermotoga2 maritima
37d1ldda_
not modelled 45.1 18
Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:SCF ubiquitin ligase complex WHB domain
38c4kkpA_
not modelled 40.2 38
PDB header:structural protein
Chain: A: PDB Molecule:rbma protein;
PDBTitle: crystal structure of vibrio cholerae rbma (crystal form 2)
39c1bf5A_
not modelled 40.1 7
PDB header:gene regulation/dna
Chain: A: PDB Molecule:signal transducer and activator of transcription 1-
PDBTitle: tyrosine phosphorylated stat-1/dna complex
40c4rh7A_
not modelled 40.1 12
PDB header:motor protein
Chain: A: PDB Molecule:green fluorescent protein/cytoplasmic dynein 2 heavy chain
PDBTitle: crystal structure of human cytoplasmic dynein 2 motor domain in2 complex with adp.vi
41c3ceyA_
not modelled 39.6 20
PDB header:transcription regulator
Chain: A: PDB Molecule:lethal(3)malignant brain tumor-like 2 protein;
PDBTitle: crystal structure of l3mbtl2
42c4ll8E_
not modelled 38.6 7
PDB header:motor protein/transport protein
Chain: E: PDB Molecule:swi5-dependent ho expression protein 3;
PDBTitle: complex of carboxy terminal domain of myo4p and she3p middle fragment
43c3q8tB_
not modelled 35.8 9
PDB header:apoptosis
Chain: B: PDB Molecule:beclin-1;
PDBTitle: crystal structure of the coiled coil domain of beclin 1, an essential2 autophagy protein
44c4cg4D_
not modelled 35.6 5
PDB header:actin-binding protein
Chain: D: PDB Molecule:pyrin;
PDBTitle: crystal structure of the chs-b30.2 domains of trim20
45c6gapB_
not modelled 35.0 11
PDB header:viral protein
Chain: B: PDB Molecule:outer capsid protein sigma-1;
PDBTitle: crystal structure of the t3d reovirus sigma1 coiled coil tail and body
46c5d3aA_
not modelled 31.7 8
PDB header:motor protein
Chain: A: PDB Molecule:kinesin-like protein kif21a;
PDBTitle: kif21a regulatory coiled coil
47d1qb5d_
not modelled 30.4 33
Fold:OB-fold
Superfamily:Bacterial enterotoxins
Family:Bacterial AB5 toxins, B-subunits
48c6ogdB_
not modelled 29.3 7
PDB header:toxin
Chain: B: PDB Molecule:toxin subunit yena2;
PDBTitle: cryo-em structure of yentca in its prepore state
49c4ll7C_
not modelled 28.8 10
PDB header:transport protein
Chain: C: PDB Molecule:swi5-dependent ho expression protein 3;
PDBTitle: structure of she3p amino terminus.
50c6hk5A_
not modelled 28.0 31
PDB header:metal binding protein
Chain: A: PDB Molecule:cooj;
PDBTitle: x-ray structure of a truncated mutant of the metallochaperone cooj2 with a high-affinity nickel-binding site
51c3vkhA_
not modelled 26.7 7
PDB header:motor protein
Chain: A: PDB Molecule:dynein heavy chain, cytoplasmic;
PDBTitle: x-ray structure of a functional full-length dynein motor domain
52d2gtsa1
not modelled 25.2 7
Fold:Ferritin-like
Superfamily:HP0062-like
Family:HP0062-like
53c5ed8A_
not modelled 25.0 15
PDB header:transport protein
Chain: A: PDB Molecule:mkiaa0668 protein;
PDBTitle: crystal structure of cc2-sun of mouse sun2
54c5tbyA_
not modelled 23.5 8
PDB header:contractile protein
Chain: A: PDB Molecule:myosin-7;
PDBTitle: human beta cardiac heavy meromyosin interacting-heads motif obtained2 by homology modeling (using swiss-model) of human sequence from3 aphonopelma homology model (pdb-3jbh), rigidly fitted to human beta-4 cardiac negatively stained thick filament 3d-reconstruction (emd-5 2240)
55c3teqB_
not modelled 22.2 9
PDB header:signaling protein
Chain: B: PDB Molecule:stromal interaction molecule 1;
PDBTitle: crystal structure of soar domain
56c3s4rB_
not modelled 21.9 11
PDB header:structural protein
Chain: B: PDB Molecule:vimentin;
PDBTitle: crystal structure of vimentin coil1a/1b fragment with a stabilizing2 mutation
57c5cqvB_
not modelled 21.8 8
PDB header:unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of uncharacterized protein q8dwv2 from streptococcus2 agalactiae
58c3vkhB_
not modelled 20.6 9
PDB header:motor protein
Chain: B: PDB Molecule:dynein heavy chain, cytoplasmic;
PDBTitle: x-ray structure of a functional full-length dynein motor domain
59d1m0wa1
not modelled 20.6 18
Fold:PreATP-grasp domain
Superfamily:PreATP-grasp domain
Family:Eukaryotic glutathione synthetase, substrate-binding domain
60c6gaoC_
not modelled 20.5 11
PDB header:viral protein
Chain: C: PDB Molecule:outer capsid protein sigma-1;
PDBTitle: crystal structure of the t1l reovirus sigma1 coiled coil tail and body
61c3jcuO_
not modelled 20.2 21
PDB header:membrane protein
Chain: O: PDB Molecule:oxygen-evolving enhancer protein 1, chloroplastic;
PDBTitle: cryo-em structure of spinach psii-lhcii supercomplex at 3.2 angstrom2 resolution
62c3a6mB_
not modelled 19.4 7
PDB header:chaperone
Chain: B: PDB Molecule:protein grpe;
PDBTitle: crystal structure of grpe from thermus thermophilus hb8
63d1vp5a_
not modelled 19.2 9
Fold:TIM beta/alpha-barrel
Superfamily:NAD(P)-linked oxidoreductase
Family:Aldo-keto reductases (NADP)
64c1dkgB_
not modelled 19.2 20
PDB header:complex (hsp24/hsp70)
Chain: B: PDB Molecule:nucleotide exchange factor grpe;
PDBTitle: crystal structure of the nucleotide exchange factor grpe2 bound to the atpase domain of the molecular chaperone dnak
65c6o7xa_
not modelled 18.8 11
PDB header:membrane protein
Chain: A: PDB Molecule:vacuolar atp synthase catalytic subunit a;
PDBTitle: saccharomyces cerevisiae v-atpase stv1-v1vo state 3
66d1kqfb2
not modelled 18.8 33
Fold:Single transmembrane helix
Superfamily:Iron-sulfur subunit of formate dehydrogenase N, transmembrane anchor
Family:Iron-sulfur subunit of formate dehydrogenase N, transmembrane anchor
67d2gu2a1
not modelled 18.8 15
Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:AstE/AspA-like
68c5cofA_
not modelled 18.6 8
PDB header:unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of uncharacterised protein q1r1x2 from escherichia2 coli uti89
69c5jxfA_
not modelled 18.4 9
PDB header:hydrolase
Chain: A: PDB Molecule:asp/glu-specific dipeptidyl-peptidase;
PDBTitle: crystal structure of flavobacterium psychrophilum dpp11 in complex2 with dipeptide arg-asp
70c5wwlN_
not modelled 18.0 10
PDB header:cell cycle
Chain: N: PDB Molecule:kinetochore protein nnf1;
PDBTitle: crystal structure of the schizogenesis pombe kinetochore mis12c2 subcomplex
71c5ywzA_
not modelled 17.6 12
PDB header:nuclear protein
Chain: A: PDB Molecule:sun domain-containing protein 1;
PDBTitle: aid-sun tandem of sun1
72c3ibpA_
not modelled 17.0 5
PDB header:cell cycle
Chain: A: PDB Molecule:chromosome partition protein mukb;
PDBTitle: the crystal structure of the dimerization domain of escherichia coli2 structural maintenance of chromosomes protein mukb
73c2j8pA_
not modelled 16.0 23
PDB header:nuclear protein
Chain: A: PDB Molecule:cleavage stimulation factor 64 kda subunit;
PDBTitle: nmr structure of c-terminal domain of human cstf-64
74c3okqA_
not modelled 16.0 14
PDB header:protein binding
Chain: A: PDB Molecule:bud site selection protein 6;
PDBTitle: crystal structure of a core domain of yeast actin nucleation cofactor2 bud6
75c5yfpE_
not modelled 15.6 9
PDB header:exocytosis
Chain: E: PDB Molecule:exocyst complex component sec10;
PDBTitle: cryo-em structure of the exocyst complex
76c5j9qH_
not modelled 15.3 14
PDB header:transferase
Chain: H: PDB Molecule:chromatin modification-related protein yng2;
PDBTitle: crystal structure of the nua4 core complex
77d1rmja_
not modelled 15.2 22
Fold:Thyroglobulin type-1 domain
Superfamily:Thyroglobulin type-1 domain
Family:Thyroglobulin type-1 domain
78c2fuqA_
not modelled 15.1 17
PDB header:sugar binding protein
Chain: A: PDB Molecule:heparinase ii protein;
PDBTitle: crystal structure of heparinase ii
79c2ch7A_
not modelled 15.0 7
PDB header:chemotaxis
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein;
PDBTitle: crystal structure of the cytoplasmic domain of a bacterial2 chemoreceptor from thermotoga maritima
80c6mi3A_
not modelled 14.9 12
PDB header:transcription
Chain: A: PDB Molecule:nf-kb essential modulator,nf-kappa-b essential modulator,
PDBTitle: structure of nemo(51-112) with n- and c-terminal coiled-coil adaptors.
81c5mqfK_
not modelled 14.9 13
PDB header:splicing
Chain: K: PDB Molecule:pre-mrna-splicing factor spf27;
PDBTitle: cryo-em structure of a human spliceosome activated for step 2 of2 splicing (c* complex)
82d2ez9a3
not modelled 14.8 22
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
83c5h5yB_
not modelled 14.6 30
PDB header:transferase
Chain: B: PDB Molecule:non-lee encoded effector protein nleb;
PDBTitle: structure of transferase mutant-c23s,c199s
84d1qnta2
not modelled 14.6 27
Fold:Ribonuclease H-like motif
Superfamily:Methylated DNA-protein cysteine methyltransferase domain
Family:Methylated DNA-protein cysteine methyltransferase domain
85d1lvfa_
not modelled 14.5 11
Fold:STAT-like
Superfamily:t-snare proteins
Family:t-snare proteins
86c3lssA_
not modelled 14.3 5
PDB header:ligase
Chain: A: PDB Molecule:seryl-trna synthetase;
PDBTitle: trypanosoma brucei seryl-trna synthetase in complex with atp
87c2narA_
not modelled 14.3 33
PDB header:protein binding
Chain: A: PDB Molecule:effector protein avr3a;
PDBTitle: solution structure of avr3a_60-147 from phytophthora infestans
88c5hyuA_
not modelled 14.1 14
PDB header:immune system
Chain: A: PDB Molecule:m protein, serotype 2.1;
PDBTitle: structure of human c4b-binding protein alpha chain ccp domains 1 and 22 in complex with the hypervariable region of group a streptococcus m23 protein
89d2hthb1
not modelled 14.1 17
Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:VPS36 N-terminal domain-like
90c2d3eD_
not modelled 14.0 7
PDB header:contractile protein
Chain: D: PDB Molecule:general control protein gcn4 and tropomyosin 1 alpha chain;
PDBTitle: crystal structure of the c-terminal fragment of rabbit skeletal alpha-2 tropomyosin
91d1gjja1
not modelled 13.8 37
Fold:LEM/SAP HeH motif
Superfamily:LEM domain
Family:LEM domain
92c5voxb_
not modelled 13.8 6
PDB header:hydrolase
Chain: B: PDB Molecule:v-type proton atpase subunit b;
PDBTitle: yeast v-atpase in complex with legionella pneumophila effector sidk2 (rotational state 1)
93d1tifa_
not modelled 13.7 29
Fold:beta-Grasp (ubiquitin-like)
Superfamily:Translation initiation factor IF3, N-terminal domain
Family:Translation initiation factor IF3, N-terminal domain
94d1iapa_
not modelled 13.4 44
Fold:Regulator of G-protein signaling, RGS
Superfamily:Regulator of G-protein signaling, RGS
Family:Regulator of G-protein signaling, RGS
95d3buxb3
not modelled 13.1 30
Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
96c3enoC_
not modelled 12.9 32
PDB header:hydrolase/unknown function
Chain: C: PDB Molecule:uncharacterized protein pf2011;
PDBTitle: crystal structure of pyrococcus furiosus pcc1 in complex2 with thermoplasma acidophilum kae1
97c3u1aC_
not modelled 12.7 11
PDB header:contractile protein
Chain: C: PDB Molecule:smooth muscle tropomyosin alpha;
PDBTitle: n-terminal 81-aa fragment of smooth muscle tropomyosin alpha
98c2muaA_
not modelled 12.6 57
PDB header:immune system
Chain: A: PDB Molecule:ring-infected erythrocyte surface antigen;
PDBTitle: shifting the polarity of some critical residues in malarial peptides2 binding to host cells is a key factor in breaking conserved antigens
99c1htjF_
not modelled 12.5 56
PDB header:signaling protein
Chain: F: PDB Molecule:kiaa0380;
PDBTitle: structure of the rgs-like domain from pdz-rhogef

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