1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	T	T	T	V	D	G	L	W	V	L	Q	A	V	T	G	V	E	Q	T	C	P	E	L	G	L	R	P	L	L	P	R	L	D	T	A	E	R	A	L	R	H	P	V	A	A	E	L	M	A	V	G	A	L	D	Q	A	G	N
Secondary structure
SS confidence
Disorder		?			?	?																																								?										?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	D	P	M	V	R	E	W	L	T	V	L	L	R	R	D	L	G	L	L	V	T	I	G	V	P	G	G	E	P	T	R	A	A	I	C	R	F	A	T	W	W	V	V	L	E	R	H	G	N	L	V	R	L	Y	P	A	G	T	A
Secondary structure
SS confidence
Disorder																																																											?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		S	D	E	A	G	A	G	E	L	V	V	G	Q	V	E	R	L	C	G	V	A	E	A	A	P	L	R	P	V	T	V	D	A	D	E	L	L	H	A	V	R	D	A	G	T	L	R	S	Y	L	L	S	Q	R	L	D	V	D	Q	L
Secondary structure
SS confidence
Disorder		?	?	?	?			?	?	?																														?	?	?	?	?	?									?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Q	M	V	T	M	A	A	D	P	T	R	S	A	H	A	T	L	V	A	L	Q	A	G	V	G	P	E	K	S	A	R	I	L	V	G	D	S	T	V	A	I	V	D	T	A	A	G	R	I	C	V	E	S	V	T	S	G	Q	R	R
Secondary structure
SS confidence
Disorder			?		?	?	?	?	?	?	?	?	?	?													?		?	?	?	?	?	?	?																			?		?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.
Sequence		Y	Q	V	L	S	P	G	S	R	S	D	I	G	G	A	V	Q	R	L	I	R	R	L	P	A	G	D	E	W	Y	S	Y	R	R	V	V
Secondary structure
SS confidence
Disorder																																?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 22%) Alpha helix ( 33%) Beta strand ( 24%)

Rank Aligned region

PDB 4kxr chain C Region: 2 - 273 Aligned: 249 Modelled: 272 Confidence: 100.0% Identity: 23% PDB header:protein transport Chain: C: PDB Molecule:espg5; PDBTitle: structure of the mycobacterium tuberculosis type vii secretion system2 chaperone espg5 in complex with pe25-ppe41 dimer Phyre2 PDB 4l4w chain B Region: 2 - 270 Aligned: 256 Modelled: 269 Confidence: 100.0% Identity: 25% PDB header:protein transport Chain: B: PDB Molecule:espg3; PDBTitle: structure of espg3 chaperone from the type vii (esx-3) secretion2 system Phyre2 PDB 5vba chain A Region: 2 - 270 Aligned: 237 Modelled: 269 Confidence: 100.0% Identity: 27% PDB header:chaperone, hydrolase Chain: A: PDB Molecule:lysozyme, esx-1 secretion-associated protein espg1 chimera; PDBTitle: structure of espg1 chaperone from the type vii (esx-1) secretion2 system determined with the assistance of n-terminal t4 lysozyme3 fusion Phyre2 PDB 4w4i chain A Region: 2 - 265 Aligned: 252 Modelled: 264 Confidence: 100.0% Identity: 23% PDB header:protein transport Chain: A: PDB Molecule:esx-3 secretion-associated protein espg3; PDBTitle: crystal structure of espg3 from the esx-3 type vii secretion system of2 m. tuberculosis Phyre2 PDB 4rcl chain B Region: 2 - 270 Aligned: 227 Modelled: 239 Confidence: 100.0% Identity: 26% PDB header:chaperone Chain: B: PDB Molecule:espg3; PDBTitle: structure of espg3 chaperone from the type vii (esx-3) secretion2 system, space group p43212 Phyre2 PDB 4rdk chain B Region: 219 - 252 Aligned: 32 Modelled: 34 Confidence: 24.3% Identity: 19% PDB header:viral protein Chain: B: PDB Molecule:capsid; PDBTitle: crystal structure of norovirus boxer p domain in complex with lewis b2 tetrasaccharide Phyre2 PDB 1hyn chain P Region: 248 - 275 Aligned: 27 Modelled: 28 Confidence: 14.1% Identity: 19% Fold: Phoshotransferase/anion transport protein Superfamily: Phoshotransferase/anion transport protein Family: Anion transport protein, cytoplasmic domain Phyre2 PDB 1hyn chain Q Region: 248 - 275 Aligned: 27 Modelled: 28 Confidence: 12.8% Identity: 19% PDB header:membrane protein Chain: Q: PDB Molecule:band 3 anion transport protein; PDBTitle: crystal structure of the cytoplasmic domain of human erythrocyte band-2 3 protein Phyre2 PDB 1rk8 chain C Region: 264 - 275 Aligned: 11 Modelled: 12 Confidence: 11.5% Identity: 55% Fold: WW domain-like Superfamily: Pym (Within the bgcn gene intron protein, WIBG), N-terminal domain Family: Pym (Within the bgcn gene intron protein, WIBG), N-terminal domain Phyre2 PDB 1rk8 chain C Region: 264 - 275 Aligned: 11 Modelled: 12 Confidence: 11.5% Identity: 55% PDB header:translation Chain: C: PDB Molecule:within the bgcn gene intron protein; PDBTitle: structure of the cytosolic protein pym bound to the mago-2 y14 core of the exon junction complex Phyre2 PDB 4qyj chain D Region: 221 - 269 Aligned: 48 Modelled: 49 Confidence: 9.7% Identity: 19% PDB header:oxidoreductase Chain: D: PDB Molecule:aldehyde dehydrogenase; PDBTitle: structure of phenylacetaldehyde dehydrogenase from pseudomonas putida2 s12 Phyre2 PDB 5iuu chain A Region: 220 - 269 Aligned: 49 Modelled: 50 Confidence: 9.5% Identity: 16% PDB header:oxidoreductase Chain: A: PDB Molecule:aldehyde dehydrogenase family protein; PDBTitle: crystal structure of indole-3-acetaldehyde dehydrogenase in apo form Phyre2 PDB 1mgt chain A domain 1 Region: 252 - 275 Aligned: 23 Modelled: 24 Confidence: 7.2% Identity: 17% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Methylated DNA-protein cysteine methyltransferase, C-terminal domain Family: Methylated DNA-protein cysteine methyltransferase, C-terminal domain Phyre2 PDB 3zdl chain B Region: 1 - 21 Aligned: 21 Modelled: 21 Confidence: 7.2% Identity: 24% PDB header:cell adhesion Chain: B: PDB Molecule:amyloid beta a4 precursor protein-binding family b member PDBTitle: vinculin head (1-258) in complex with a riam fragment Phyre2 PDB 1g26 chain A Region: 262 - 270 Aligned: 8 Modelled: 9 Confidence: 6.7% Identity: 63% Fold: Knottins (small inhibitors, toxins, lectins) Superfamily: Granulin repeat Family: Granulin repeat Phyre2 PDB 3ed6 chain B Region: 221 - 269 Aligned: 48 Modelled: 49 Confidence: 6.3% Identity: 23% PDB header:oxidoreductase Chain: B: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: 1.7 angstrom resolution crystal structure of betaine aldehyde2 dehydrogenase (betb) from staphylococcus aureus Phyre2 PDB 1fwx chain B Region: 216 - 246 Aligned: 31 Modelled: 31 Confidence: 6.2% Identity: 6% PDB header:oxidoreductase Chain: B: PDB Molecule:nitrous oxide reductase; PDBTitle: crystal structure of nitrous oxide reductase from p. denitrificans Phyre2 PDB 1mo6 chain A domain 2 Region: 265 - 272 Aligned: 7 Modelled: 7 Confidence: 6.2% Identity: 43% Fold: Anti-LPS factor/recA domain Superfamily: RecA protein, C-terminal domain Family: RecA protein, C-terminal domain Phyre2 PDB 1u94 chain A domain 2 Region: 265 - 272 Aligned: 7 Modelled: 8 Confidence: 6.0% Identity: 86% Fold: Anti-LPS factor/recA domain Superfamily: RecA protein, C-terminal domain Family: RecA protein, C-terminal domain Phyre2 PDB 2zl5 chain A Region: 219 - 246 Aligned: 26 Modelled: 28 Confidence: 5.8% Identity: 23% PDB header:viral protein Chain: A: PDB Molecule:58 kd capsid protein; PDBTitle: atomic resolution structural characterization of2 recognition of histo-blood group antigen by norwalk virus Phyre2 1 c4kxrC_ 2 c4l4wB_ 3 c5vbaA_ 4 c4w4iA_ 5 c4rclB_ 6 c4rdkB_ 7 d1hynp_ 8 c1hynQ_ 9 d1rk8c_ 10 c1rk8C_ 11 c4qyjD_ 12 c5iuuA_ 13 d1mgta1 14 c3zdlB_ 15 d1g26a_ 16 c3ed6B_ 17 c1fwxB_ 18 d1mo6a2 19 d1u94a2 20 c2zl5A_ 21 22 23 24 25 26 27