1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	A	D	T	I	Q	V	T	P	Q	M	L	R	S	T	A	N	D	I	Q	A	N	M	E	Q	A	M	G	I	A	K	G	Y	L	A	N	Q	E	N	V	M	N	P	A	T	W	S	G	T	G	V	V	A	S	H	M	T	A	T	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?							?	?							?								?							?	?		?														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.
Sequence		I	T	N	E	L	N	K	V	L	T	G	G	T	R	L	A	E	G	L	V	Q	A	A	A	L	M	E	G	H	E	A	D	S	Q	T	A	F	Q	A	L	F	G	A	S	H	G	S
Secondary structure
SS confidence
Disorder												?															?	?	?	?		?	?										?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 26%) Alpha helix ( 92%) Beta strand ( 0%)

Rank Aligned region

PDB 1wa8 chain A domain 1 Region: 5 - 102 Aligned: 96 Modelled: 98 Confidence: 96.6% Identity: 13% Fold: Ferritin-like Superfamily: EsxAB dimer-like Family: ESAT-6 like Phyre2 PDB 2vs0 chain B Region: 5 - 87 Aligned: 81 Modelled: 83 Confidence: 95.5% Identity: 15% PDB header:cell invasion Chain: B: PDB Molecule:virulence factor esxa; PDBTitle: structural analysis of homodimeric staphylococcal aureus2 virulence factor esxa Phyre2 PDB 4iog chain D Region: 5 - 87 Aligned: 81 Modelled: 83 Confidence: 94.1% Identity: 12% PDB header:unknown function Chain: D: PDB Molecule:secreted protein esxb; PDBTitle: the crystal structure of a secreted protein esxb (wild-type, in p212 space group) from bacillus anthracis str. sterne Phyre2 PDB 3zbh chain C Region: 8 - 98 Aligned: 89 Modelled: 91 Confidence: 93.3% Identity: 15% PDB header:unknown function Chain: C: PDB Molecule:esxa; PDBTitle: geobacillus thermodenitrificans esxa crystal form i Phyre2 PDB 3gvm chain A Region: 5 - 96 Aligned: 90 Modelled: 92 Confidence: 91.4% Identity: 20% PDB header:viral protein Chain: A: PDB Molecule:putative uncharacterized protein sag1039; PDBTitle: structure of the homodimeric wxg-100 family protein from streptococcus2 agalactiae Phyre2 PDB 4lws chain A Region: 5 - 103 Aligned: 97 Modelled: 99 Confidence: 86.2% Identity: 18% PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: esxa : esxb (semet) hetero-dimer from thermomonospora curvata Phyre2 PDB 4lws chain B Region: 2 - 87 Aligned: 84 Modelled: 86 Confidence: 26.8% Identity: 10% PDB header:unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: esxa : esxb (semet) hetero-dimer from thermomonospora curvata Phyre2 PDB 1wa8 chain B domain 1 Region: 5 - 97 Aligned: 91 Modelled: 93 Confidence: 26.5% Identity: 18% Fold: Ferritin-like Superfamily: EsxAB dimer-like Family: ESAT-6 like Phyre2 PDB 1st6 chain A domain 7 Region: 9 - 39 Aligned: 31 Modelled: 31 Confidence: 18.9% Identity: 32% Fold: Four-helical up-and-down bundle Superfamily: alpha-catenin/vinculin-like Family: alpha-catenin/vinculin Phyre2 PDB 1onr chain A Region: 5 - 48 Aligned: 40 Modelled: 44 Confidence: 18.2% Identity: 28% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 2l92 chain A Region: 39 - 50 Aligned: 12 Modelled: 12 Confidence: 17.7% Identity: 42% PDB header:dna binding protein Chain: A: PDB Molecule:histone family protein nucleoid-structuring protein h-ns; PDBTitle: solution structure of the c-terminal domain of h-ns like protein bv3f Phyre2 PDB 3m16 chain A Region: 5 - 48 Aligned: 40 Modelled: 44 Confidence: 16.6% Identity: 28% PDB header:transferase Chain: A: PDB Molecule:transaldolase; PDBTitle: structure of a transaldolase from oleispira antarctica Phyre2 PDB 2kg7 chain B Region: 5 - 97 Aligned: 91 Modelled: 93 Confidence: 16.1% Identity: 8% PDB header:unknown function Chain: B: PDB Molecule:esat-6-like protein esxh; PDBTitle: structure and features of the complex formed by the tuberculosis2 virulence factors rv0287 and rv0288 Phyre2 PDB 2jr1 chain A Region: 44 - 64 Aligned: 21 Modelled: 21 Confidence: 14.7% Identity: 38% PDB header:dna binding protein Chain: A: PDB Molecule:virulence regulator; PDBTitle: solution structure of the dna binding domain of a nucleoid-associated2 protein, h-ns, from the phytopathogen xylella fastidiosa. Phyre2 PDB 2e1d chain A domain 1 Region: 5 - 48 Aligned: 40 Modelled: 44 Confidence: 14.4% Identity: 23% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 3cq0 chain B Region: 14 - 48 Aligned: 35 Modelled: 35 Confidence: 10.6% Identity: 31% PDB header:transferase Chain: B: PDB Molecule:putative transaldolase ygr043c; PDBTitle: crystal structure of tal2_yeast Phyre2 PDB 1f05 chain A Region: 5 - 48 Aligned: 40 Modelled: 44 Confidence: 9.9% Identity: 23% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 3hjz chain A Region: 5 - 48 Aligned: 40 Modelled: 44 Confidence: 9.5% Identity: 28% PDB header:transferase Chain: A: PDB Molecule:transaldolase b; PDBTitle: the structure of an aldolase from prochlorococcus marinus Phyre2 PDB 3phu chain A Region: 10 - 48 Aligned: 39 Modelled: 39 Confidence: 9.1% Identity: 10% PDB header:hydrolase Chain: A: PDB Molecule:rna-directed rna polymerase l; PDBTitle: otu domain of crimean congo hemorrhagic fever virus Phyre2 PDB 2khv chain A Region: 13 - 48 Aligned: 34 Modelled: 36 Confidence: 8.2% Identity: 26% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:phage integrase; PDBTitle: solution nmr structure of protein nmul_a0922 from2 nitrosospira multiformis. northeast structural genomics3 consortium target nmr38b. Phyre2 1 d1wa8a1 2 c2vs0B_ 3 c4iogD_ 4 c3zbhC_ 5 c3gvmA_ 6 c4lwsA_ 7 c4lwsB_ 8 d1wa8b1 9 d1st6a7 10 d1onra_ 11 c2l92A_ 12 c3m16A_ 13 c2kg7B_ 14 c2jr1A_ 15 d2e1da1 16 c3cq0B_ 17 d1f05a_ 18 c3hjzA_ 19 c3phuA_ 20 c2khvA_ 21 22 23 24 25 26 27 28