1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	L	S	L	S	N	R	D	Q	N	S	G	H	L	F	Y	N	R	R	L	R	A	A	T	T	R	F	S	V	R	M	K	H	D	D	R	K	Q	T	A	A	L	A	L	S	M	V	L	V	A	I	A	A	G	W	M	M	L	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		N	V	L	K	P	T	G	I	V	G	D	S	A	I	I	G	D	R	D	S	G	A	L	Y	A	R	I	D	G	R	L	Y	P	A	L	N	L	T	S	A	R	L	A	T	G	T	A	G	Q	P	T	W	V	K	P	A	E	I	A	K
Secondary structure
SS confidence
Disorder						?	?	?	?		?	?																																			?	?	?	?	?			?						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Y	P	T	G	P	L	V	G	I	P	G	A	P	A	A	M	P	V	N	R	G	A	V	S	A	W	A	V	C	D	T	A	G	R	P	R	S	A	D	K	P	V	V	T	S	I	A	G	P	I	T	G	G	G	R	A	T	H	L	R
Secondary structure
SS confidence
Disorder		?		?															?	?	?	?	?	?	?						?	?	?	?	?	?	?	?	?	?	?								?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		D	D	A	G	L	L	V	T	F	D	G	S	T	Y	V	I	W	G	G	K	R	S	Q	I	D	P	T	N	R	A	V	T	L	S	L	G	L	D	P	G	V	T	S	P	I	Q	I	S	R	A	L	F	D	G	L	P	A	T	E	P
Secondary structure
SS confidence
Disorder		?	?	?																								?		?								?				?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	R	V	P	A	V	P	E	A	G	T	P	S	T	W	V	P	G	A	R	V	G	S	V	L	Q	A	Q	T	A	G	G	G	S	Q	F	Y	V	L	L	P	D	G	V	Q	K	I	S	S	F	V	A	D	L	L	R	S	A	N	S
Secondary structure
SS confidence
Disorder								?	?	?	?	?	?	?	?	?	?	?											?	?	?																													?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		Y	G	A	A	A	P	R	V	V	T	P	D	V	L	V	H	T	P	Q	V	T	S	L	P	V	E	Y	Y	P	A	G	R	L	N	F	V	D	T	A	A	D	P	T	T	C	V	S	W	E	K	A	S	T	D	P	Q	A	R	V	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?							?		?	?												?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		V	Y	N	G	R	G	L	P	V	P	P	S	M	D	S	R	I	V	R	L	V	R	D	D	R	A	P	A	S	V	V	A	T	Q	V	L	V	L	P	G	A	A	N	F	V	T	S	T	S	G	V	I	T	A	E	S	R	E	S	L
Secondary structure
SS confidence
Disorder			?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		F	W	V	S	G	N	G	V	R	F	G	I	A	N	D	E	A	T	L	R	A	L	G	L	D	P	G	A	A	V	Q	A	P	W	P	L	L	R	T	F	A	A	G	P	A	L	S	R	D	A	A	L	L	A	R	D	T	V	P	T
Secondary structure
SS confidence
Disorder														?		?										?		?	?	?													?			?										?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.
Sequence		L	G	Q	V	A	I	V	T	T	T	A	K	A	G	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 40%) Alpha helix ( 20%) Beta strand ( 21%) TM helix ( 4%) (View membrane topology prediction)

Rank Aligned region

PDB 4kk7 chain A Region: 73 - 473 Aligned: 382 Modelled: 401 Confidence: 100.0% Identity: 35% PDB header:protein transport Chain: A: PDB Molecule:esx-1 secretion system protein eccb1; PDBTitle: structure of eccb1 from the type vii (esx-1) secretion system of2 mycobacterium tuberculosis. Phyre2 PDB 5cyu chain A Region: 73 - 473 Aligned: 375 Modelled: 401 Confidence: 100.0% Identity: 35% PDB header:membrane protein Chain: A: PDB Molecule:conserved membrane protein; PDBTitle: structure of the soluble domain of eccb1 from the mycobacterium2 smegmatis esx-1 secretion system. Phyre2 PDB 6nav chain I Region: 43 - 88 Aligned: 44 Modelled: 46 Confidence: 42.8% Identity: 18% PDB header:structural protein Chain: I: PDB Molecule:m9ud72; PDBTitle: cryo-em reconstruction of sulfolobus islandicus lal14/1 pilus Phyre2 PDB 2fb5 chain A domain 1 Region: 74 - 94 Aligned: 21 Modelled: 21 Confidence: 36.8% Identity: 19% Fold: YojJ-like Superfamily: YojJ-like Family: YojJ-like Phyre2 PDB 1k6n chain H Region: 74 - 123 Aligned: 46 Modelled: 50 Confidence: 30.3% Identity: 22% PDB header:photosynthesis Chain: H: PDB Molecule:photosynthetic reaction center h subunit; PDBTitle: e(l212)a,d(l213)a double mutant structure of photosynthetic reaction2 center from rhodobacter sphaeroides Phyre2 PDB 2i5n chain H domain 1 Region: 74 - 123 Aligned: 46 Modelled: 50 Confidence: 30.3% Identity: 20% Fold: PRC-barrel domain Superfamily: PRC-barrel domain Family: Photosynthetic reaction centre, H-chain, cytoplasmic domain Phyre2 PDB 2i5n chain H Region: 72 - 123 Aligned: 48 Modelled: 52 Confidence: 23.6% Identity: 19% PDB header:photosynthesis Chain: H: PDB Molecule:reaction center protein h chain; PDBTitle: 1.96 a x-ray structure of photosynthetic reaction center from2 rhodopseudomonas viridis:crystals grown by microfluidic technique Phyre2 PDB 2wmm chain A Region: 8 - 52 Aligned: 43 Modelled: 45 Confidence: 21.1% Identity: 16% PDB header:cell cycle Chain: A: PDB Molecule:chromosome partition protein mukb; PDBTitle: crystal structure of the hinge domain of mukb Phyre2 PDB 1rzh chain H domain 1 Region: 74 - 123 Aligned: 46 Modelled: 50 Confidence: 18.5% Identity: 22% Fold: PRC-barrel domain Superfamily: PRC-barrel domain Family: Photosynthetic reaction centre, H-chain, cytoplasmic domain Phyre2 PDB 2ixs chain B Region: 416 - 453 Aligned: 38 Modelled: 38 Confidence: 17.4% Identity: 11% PDB header:hydrolase Chain: B: PDB Molecule:sdai restriction endonuclease; PDBTitle: structure of sdai restriction endonuclease Phyre2 PDB 5xef chain A Region: 14 - 34 Aligned: 21 Modelled: 21 Confidence: 16.9% Identity: 5% PDB header:chaperone Chain: A: PDB Molecule:flagellar protein flis; PDBTitle: crystal structure of flagellar chaperone from bacteria Phyre2 PDB 1vh6 chain A Region: 14 - 34 Aligned: 21 Modelled: 18 Confidence: 14.3% Identity: 19% Fold: Four-helical up-and-down bundle Superfamily: Flagellar export chaperone FliS Family: Flagellar export chaperone FliS Phyre2 PDB 1vh6 chain A Region: 14 - 34 Aligned: 21 Modelled: 18 Confidence: 14.3% Identity: 19% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:flagellar protein flis; PDBTitle: crystal structure of a flagellar protein Phyre2 PDB 3k1i chain A Region: 14 - 34 Aligned: 21 Modelled: 21 Confidence: 13.3% Identity: 10% PDB header:chaperone Chain: A: PDB Molecule:flagellar protein; PDBTitle: crystal strcture of flis-hp1076 complex in h. pylori Phyre2 PDB 5mrw chain L Region: 40 - 64 Aligned: 24 Modelled: 25 Confidence: 12.7% Identity: 13% PDB header:hydrolase Chain: L: PDB Molecule:potassium-transporting atpase kdpf subunit; PDBTitle: structure of the kdpfabc complex Phyre2 PDB 6hrb chain D Region: 40 - 64 Aligned: 24 Modelled: 25 Confidence: 12.7% Identity: 13% PDB header:membrane protein Chain: D: PDB Molecule:potassium-transporting atpase kdpf subunit; PDBTitle: cryo-em structure of the kdpfabc complex in an e2 inward-facing state2 (state 2) Phyre2 PDB 5mrw chain D Region: 40 - 64 Aligned: 24 Modelled: 25 Confidence: 12.7% Identity: 13% PDB header:hydrolase Chain: D: PDB Molecule:potassium-transporting atpase kdpf subunit; PDBTitle: structure of the kdpfabc complex Phyre2 PDB 5mrw chain H Region: 40 - 64 Aligned: 24 Modelled: 25 Confidence: 12.7% Identity: 13% PDB header:hydrolase Chain: H: PDB Molecule:potassium-transporting atpase kdpf subunit; PDBTitle: structure of the kdpfabc complex Phyre2 PDB 6hra chain D Region: 40 - 64 Aligned: 24 Modelled: 25 Confidence: 12.7% Identity: 13% PDB header:membrane protein Chain: D: PDB Molecule:potassium-transporting atpase kdpf subunit; PDBTitle: cryo-em structure of the kdpfabc complex in an e1 outward-facing state2 (state 1) Phyre2 PDB 1y7m chain A domain 1 Region: 65 - 91 Aligned: 27 Modelled: 27 Confidence: 12.1% Identity: 15% Fold: L,D-transpeptidase catalytic domain-like Superfamily: L,D-transpeptidase catalytic domain-like Family: L,D-transpeptidase catalytic domain-like Phyre2 1 c4kk7A_ 2 c5cyuA_ 3 c6navI_ 4 d2fb5a1 5 c1k6nH_ 6 d2i5nh1 7 c2i5nH_ 8 c2wmmA_ 9 d1rzhh1 10 c2ixsB_ 11 c5xefA_ 12 d1vh6a_ 13 c1vh6A_ 14 c3k1iA_ 15 c5mrwL_ 16 c6hrbD_ 17 c5mrwD_ 18 c5mrwH_ 19 c6hraD_ 20 d1y7ma1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50