1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	D	A	A	T	T	R	V	G	L	T	D	L	T	F	R	L	L	R	E	S	F	A	D	A	V	S	W	V	A	K	N	L	P	A	R	P	A	V	P	V	L	S	G	V	L	L	T	G	S	D	N	G	L	T	I	S	G	F	D
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?																						?	?			?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Y	E	V	S	A	E	A	Q	V	G	A	E	I	V	S	P	G	S	V	L	V	S	G	R	L	L	S	D	I	T	R	A	L	P	N	K	P	V	D	V	H	V	E	G	N	R	V	A	L	T	C	G	N	A	R	F	S	L	P	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		M	P	V	E	D	Y	P	T	L	P	T	L	P	E	E	T	G	L	L	P	A	E	L	F	A	E	A	I	S	Q	V	A	I	A	A	G	R	D	D	T	L	P	M	L	T	G	I	R	V	E	I	L	G	E	T	V	V	L	A	A
Secondary structure
SS confidence
Disorder							?		?			?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	D	R	F	R	L	A	V	R	E	L	K	W	S	A	S	S	P	D	I	E	A	A	V	L	V	P	A	K	T	L	A	E	A	A	K	A	G	I	G	G	S	D	V	R	L	S	L	G	T	G	P	G	V	G	K	D	G	L	L
Secondary structure
SS confidence
Disorder															?	?	?	?	?	?	?																															?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		G	I	S	G	N	G	K	R	S	T	T	R	L	L	D	A	E	F	P	K	F	R	Q	L	L	P	T	E	H	T	A	V	A	T	M	D	V	A	E	L	I	E	A	I	K	L	V	A	L	V	A	D	R	G	A	Q	V	R	M	E
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		F	A	D	G	S	V	R	L	S	A	G	A	D	D	V	G	R	A	E	E	D	L	V	V	D	Y	A	G	E	P	L	T	I	A	F	N	P	T	Y	L	T	D	G	L	S	S	L	R	S	E	R	V	S	F	G	F	T	T	A	G
Secondary structure
SS confidence
Disorder														?	?	?	?	?																																											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.
Sequence		K	P	A	L	L	R	P	V	S	G	D	D	R	P	V	A	G	L	N	G	N	G	P	F	P	A	V	S	T	D	Y	V	Y	L	L	M	P	V	R	L	P	G
Secondary structure
SS confidence
Disorder											?	?	?	?	?			?	?	?	?	?	?	?	?	?	?													?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 14%) Alpha helix ( 20%) Beta strand ( 45%)

Rank Aligned region

PDB 3p16 chain A Region: 12 - 400 Aligned: 375 Modelled: 389 Confidence: 100.0% Identity: 100% PDB header:transferase Chain: A: PDB Molecule:dna polymerase iii subunit beta; PDBTitle: crystal structure of dna polymerase iii sliding clamp Phyre2 PDB 6e8e chain A Region: 13 - 401 Aligned: 361 Modelled: 370 Confidence: 100.0% Identity: 30% PDB header:dna binding protein Chain: A: PDB Molecule:beta sliding clamp,dna mismatch repair protein mutl; PDBTitle: crystal structure of the escherichia coli sliding clamp-mutl complex. Phyre2 PDB 6p81 chain A Region: 7 - 400 Aligned: 364 Modelled: 376 Confidence: 100.0% Identity: 29% PDB header:transferase/antibiotic Chain: A: PDB Molecule:ubiquitin-like protein smt3,beta sliding clamp; PDBTitle: structure of dna polymerase iii, beta subunit/ beta sliding clamp from2 klebsiella pneumoniae, expressed with an n-terminal his-smt3 fusion3 tag, in complex with griselimycin Phyre2 PDB 1vpk chain A Region: 12 - 401 Aligned: 364 Modelled: 372 Confidence: 100.0% Identity: 26% PDB header:transferase Chain: A: PDB Molecule:dna polymerase iii, beta subunit; PDBTitle: crystal structure of dna polymerase iii, beta subunit (tm0262) from2 thermotoga maritima at 2.00 a resolution Phyre2 PDB 1unn chain A Region: 13 - 400 Aligned: 362 Modelled: 370 Confidence: 100.0% Identity: 30% PDB header:beta-clamp Chain: A: PDB Molecule:dna polymerase iii beta subunit; PDBTitle: complex of beta-clamp processivity factor and little finger domain of2 poliv Phyre2 PDB 6e8d chain A Region: 11 - 399 Aligned: 361 Modelled: 371 Confidence: 100.0% Identity: 28% PDB header:dna binding protein Chain: A: PDB Molecule:beta sliding clamp,dna mismatch repair protein mutl; PDBTitle: crystal structure of the bacillus subtilis sliding clamp-mutl complex. Phyre2 PDB 5w7z chain A Region: 11 - 400 Aligned: 365 Modelled: 372 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:dna polymerase iii subunit beta; PDBTitle: crystal structure of dna polymerase iii subunit beta from rickettsia2 conorii Phyre2 PDB 4tr6 chain A Region: 11 - 399 Aligned: 364 Modelled: 371 Confidence: 100.0% Identity: 29% PDB header:dna binding protein Chain: A: PDB Molecule:dna polymerase iii subunit beta; PDBTitle: crystal structure of dna polymerase sliding clamp from bacillus2 subtilis Phyre2 PDB 4tsz chain M Region: 12 - 400 Aligned: 359 Modelled: 369 Confidence: 100.0% Identity: 30% PDB header:transferase Chain: M: PDB Molecule:dna polymerase iii subunit beta; PDBTitle: crystal structure of dna polymerase sliding clamp from pseudomonas2 aeruginosa with ligand Phyre2 PDB 2awa chain B Region: 11 - 399 Aligned: 364 Modelled: 372 Confidence: 100.0% Identity: 28% PDB header:transferase Chain: B: PDB Molecule:dna polymerase iii, beta chain; PDBTitle: crystal structure of dna polymerase iii, beta chain (ec 2.7.7.7)2 (np_344555.1) from streptococcus pneumoniae tigr4 at 2.50 a3 resolution Phyre2 PDB 6ap4 chain B Region: 11 - 398 Aligned: 363 Modelled: 370 Confidence: 100.0% Identity: 29% PDB header:transferase Chain: B: PDB Molecule:dna polymerase iii subunit beta; PDBTitle: crystal structure of the dna polymerase iii subunit beta from2 acinetobacter baumannii Phyre2 PDB 4trt chain B Region: 13 - 399 Aligned: 356 Modelled: 370 Confidence: 100.0% Identity: 28% PDB header:transferase Chain: B: PDB Molecule:dna polymerase iii subunit beta; PDBTitle: deinococcus radiodurans dna polymerase iii subunit beta Phyre2 PDB 5wce chain B Region: 13 - 400 Aligned: 360 Modelled: 370 Confidence: 100.0% Identity: 27% PDB header:transferase Chain: B: PDB Molecule:dna polymerase iii subunit beta; PDBTitle: caulobacter crescentus pol iii beta Phyre2 PDB 3t0p chain B Region: 13 - 400 Aligned: 362 Modelled: 368 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: B: PDB Molecule:dna polymerase iii, beta subunit; PDBTitle: crystal structure of a putative dna polymerase iii beta subunit2 (eubrec_0002; ere_29750) from eubacterium rectale atcc 33656 at 2.263 a resolution Phyre2 PDB 4rki chain A Region: 13 - 400 Aligned: 365 Modelled: 388 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:dna polymerase iii subunit beta; PDBTitle: crystal structure of sliding beta clamp from helicobacter pylori Phyre2 PDB 6dj8 chain B Region: 12 - 400 Aligned: 360 Modelled: 370 Confidence: 100.0% Identity: 16% PDB header:dna binding protein Chain: B: PDB Molecule:beta sliding clamp; PDBTitle: structure of dna polymerase iii subunit beta from borrelia burgdorferi2 in complex with a natural product Phyre2 PDB 6deg chain A Region: 12 - 400 Aligned: 345 Modelled: 367 Confidence: 100.0% Identity: 27% PDB header:dna binding protein Chain: A: PDB Molecule:beta sliding clamp; PDBTitle: crystal structure of a dna polymerase iii subunit beta dnan sliding2 clamp from bartonella birtlesii ll-wm9 Phyre2 PDB 1rwz chain A Region: 136 - 397 Aligned: 227 Modelled: 247 Confidence: 100.0% Identity: 20% PDB header:replication Chain: A: PDB Molecule:dna polymerase sliding clamp; PDBTitle: crystal structure of proliferating cell nuclear antigen (pcna) from a.2 fulgidus Phyre2 PDB 1vpk chain A domain 3 Region: 262 - 401 Aligned: 122 Modelled: 122 Confidence: 100.0% Identity: 30% Fold: DNA clamp Superfamily: DNA clamp Family: DNA polymerase III, beta subunit Phyre2 PDB 1ok7 chain A domain 3 Region: 262 - 400 Aligned: 121 Modelled: 121 Confidence: 100.0% Identity: 28% Fold: DNA clamp Superfamily: DNA clamp Family: DNA polymerase III, beta subunit Phyre2 1 c3p16A_ 2 c6e8eA_ 3 c6p81A_ 4 c1vpkA_ 5 c1unnA_ 6 c6e8dA_ 7 c5w7zA_ 8 c4tr6A_ 9 c4tszM_ 10 c2awaB_ 11 c6ap4B_ 12 c4trtB_ 13 c5wceB_ 14 c3t0pB_ 15 c4rkiA_ 16 c6dj8B_ 17 c6degA_ 18 c1rwzA_ 19 d1vpka3 20 d1ok7a3 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94