1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	G	H	R	V	D	T	L	S	D	R	Q	R	A	N	L	T	T	G	A	T	D	R	A	I	R	L	V	V	L	A	L	L	T	V	D	G	V	V	S	A	L	A	G	A	L	L	M	P	W	Y	I	G	S	A	P	F	P	I	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	L	I	S	G	L	V	N	A	A	L	V	W	A	A	A	R	W	T	T	S	S	R	V	A	A	L	P	L	W	A	W	L	L	T	V	A	A	M	S	F	G	G	P	G	D	D	V	I	L	G	G	Q	G	L	L	V	Y	G	A
Secondary structure
SS confidence
Disorder																		?	?			?	?	?																														?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.
Sequence		L	V	F	V	V	A	G	A	V	P	P	A	W	V	L	W	R	R	R	V	Q	A	D	G	S	G
Secondary structure
SS confidence
Disorder																		?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 27%) Alpha helix ( 75%) Beta strand ( 2%) TM helix ( 53%) (View membrane topology prediction)

Rank Aligned region

PDB 1dsj chain A Region: 31 - 53 Aligned: 23 Modelled: 23 Confidence: 13.1% Identity: 22% PDB header:viral peptide Chain: A: PDB Molecule:vpr protein; PDBTitle: nmr solution structure of vpr50_75, 20 structures Phyre2 PDB 6hwh chain B Region: 14 - 81 Aligned: 67 Modelled: 68 Confidence: 10.6% Identity: 22% PDB header:electron transport Chain: B: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur subunit; PDBTitle: structure of a functional obligate respiratory supercomplex from2 mycobacterium smegmatis Phyre2 PDB 5z62 chain N Region: 121 - 142 Aligned: 22 Modelled: 22 Confidence: 9.0% Identity: 27% PDB header:electron transport Chain: N: PDB Molecule:cytochrome c oxidase subunit ndufa4; PDBTitle: structure of human cytochrome c oxidase Phyre2 PDB 4e18 chain B Region: 12 - 28 Aligned: 17 Modelled: 17 Confidence: 9.0% Identity: 53% PDB header:cell adhesion Chain: B: PDB Molecule:catenin alpha-1; PDBTitle: alpha-e-catenin is an autoinhibited molecule that co-activates2 vinculin Phyre2 PDB 2yev chain C Region: 14 - 49 Aligned: 36 Modelled: 36 Confidence: 5.7% Identity: 28% PDB header:electron transport Chain: C: PDB Molecule:caa3-type cytochrome oxidase subunit iv; PDBTitle: structure of caa3-type cytochrome oxidase Phyre2 1 c1dsjA_ 2 c6hwhB_ 3 c5z62N_ 4 c4e18B_ 5 c2yevC_