1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	S	P	L	S	P	R	I	I	A	A	F	T	T	A	V	G	A	A	A	I	G	L	A	V	A	T	A	G	T	A	G	A	N	T	K	D	E	A	F	I	A	Q	M	E	S	I	G	V	T	F	S	S	P	Q	V	A	T	Q
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																				?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.
Sequence		Q	A	Q	L	V	C	K	K	L	A	S	G	E	T	G	T	E	I	A	E	E	V	L	S	Q	T	N	L	T	T	K	Q	A	A	Y	F	V	V	D	A	T	K	A	Y	C	P	Q	Y	A	S	Q	L	T
Secondary structure
SS confidence
Disorder												?			?										?		?	?	?	?																						?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 23%) Alpha helix ( 67%) Beta strand ( 0%) TM helix ( 14%) (View membrane topology prediction)

Rank Aligned region

PDB 6c3r chain B Region: 66 - 108 Aligned: 43 Modelled: 43 Confidence: 37.1% Identity: 14% PDB header:viral protein Chain: B: PDB Molecule:cricket paralysis virus 1a protein; PDBTitle: cricket paralysis virus rnai suppressor protein crpv-1a Phyre2 PDB 2csu chain A domain 3 Region: 35 - 61 Aligned: 27 Modelled: 27 Confidence: 33.1% Identity: 19% Fold: Flavodoxin-like Superfamily: Succinyl-CoA synthetase domains Family: Succinyl-CoA synthetase domains Phyre2 PDB 3pvs chain A Region: 39 - 104 Aligned: 58 Modelled: 66 Confidence: 27.3% Identity: 17% PDB header:recombination Chain: A: PDB Molecule:replication-associated recombination protein a; PDBTitle: structure and biochemical activities of escherichia coli mgsa Phyre2 PDB 5uqd chain A Region: 37 - 53 Aligned: 17 Modelled: 17 Confidence: 20.2% Identity: 24% PDB header:oxidoreductase Chain: A: PDB Molecule:dumpy: shorter than wild-type; PDBTitle: dpy-21 in complex with fe(ii) and alpha-ketoglutarate Phyre2 PDB 2j9g chain A domain 2 Region: 3 - 62 Aligned: 54 Modelled: 60 Confidence: 19.3% Identity: 22% Fold: PreATP-grasp domain Superfamily: PreATP-grasp domain Family: BC N-terminal domain-like Phyre2 PDB 1vjq chain B Region: 34 - 53 Aligned: 20 Modelled: 20 Confidence: 17.8% Identity: 20% PDB header:structural genomics, de novo protein Chain: B: PDB Molecule:designed protein; PDBTitle: designed protein based on backbone conformation of2 procarboxypeptidase-a (1aye) with sidechains chosen for maximal3 predicted stability. Phyre2 PDB 4rl6 chain A Region: 6 - 52 Aligned: 47 Modelled: 47 Confidence: 17.5% Identity: 11% PDB header:oxidoreductase Chain: A: PDB Molecule:saccharopine dehydrogenase; PDBTitle: crystal structure of the q04l03_strp2 protein from streptococcus2 pneumoniae. northeast structural genomics consortium target spr105 Phyre2 PDB 1mke chain A domain 1 Region: 49 - 71 Aligned: 23 Modelled: 23 Confidence: 17.4% Identity: 17% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Enabled/VASP homology 1 domain (EVH1 domain) Phyre2 PDB 1yqg chain A domain 1 Region: 39 - 96 Aligned: 58 Modelled: 58 Confidence: 16.8% Identity: 14% Fold: 6-phosphogluconate dehydrogenase C-terminal domain-like Superfamily: 6-phosphogluconate dehydrogenase C-terminal domain-like Family: ProC C-terminal domain-like Phyre2 PDB 2ekc chain A Region: 49 - 84 Aligned: 34 Modelled: 36 Confidence: 16.2% Identity: 26% PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5 Phyre2 PDB 3g2b chain A Region: 61 - 95 Aligned: 35 Modelled: 35 Confidence: 13.8% Identity: 11% PDB header:biosynthetic protein Chain: A: PDB Molecule:coenzyme pqq synthesis protein d; PDBTitle: crystal structure of pqqd from xanthomonas campestris Phyre2 PDB 5k9x chain A Region: 49 - 84 Aligned: 34 Modelled: 32 Confidence: 12.3% Identity: 24% PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: crystal structure of tryptophan synthase alpha chain from legionella2 pneumophila subsp. pneumophila Phyre2 PDB 3ss4 chain C Region: 40 - 55 Aligned: 16 Modelled: 16 Confidence: 12.2% Identity: 38% PDB header:hydrolase Chain: C: PDB Molecule:glutaminase c; PDBTitle: crystal structure of mouse glutaminase c, phosphate-bound form Phyre2 PDB 6g2d chain C Region: 3 - 69 Aligned: 61 Modelled: 67 Confidence: 11.8% Identity: 13% PDB header:ligase Chain: C: PDB Molecule:acetyl-coa carboxylase 1; PDBTitle: citrate-induced acetyl-coa carboxylase (acc-cit) filament at 5.4 a2 resolution Phyre2 PDB 5dgg chain B Region: 30 - 51 Aligned: 22 Modelled: 22 Confidence: 11.3% Identity: 27% PDB header:unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: central domain of uncharacterized lpg1148 protein from legionella2 pneumophila Phyre2 PDB 4ina chain A Region: 39 - 52 Aligned: 14 Modelled: 14 Confidence: 11.0% Identity: 14% PDB header:oxidoreductase Chain: A: PDB Molecule:saccharopine dehydrogenase; PDBTitle: crystal structure of the q7mss8_wolsu protein from wolinella2 succinogenes. northeast structural genomics consortium target wsr35 Phyre2 PDB 6jx3 chain B Region: 60 - 95 Aligned: 36 Modelled: 36 Confidence: 10.8% Identity: 19% PDB header:peptide binding protein Chain: B: PDB Molecule:tfub1; PDBTitle: lasso peptide synthetase b1 complexed with the leader peptide Phyre2 PDB 2lwe chain A Region: 39 - 53 Aligned: 15 Modelled: 15 Confidence: 10.6% Identity: 20% PDB header:signaling protein Chain: A: PDB Molecule:probable atp-dependent rna helicase ddx58; PDBTitle: solution structure of mutant (t170e) second card of human rig-i Phyre2 PDB 5v1u chain B Region: 60 - 95 Aligned: 36 Modelled: 36 Confidence: 10.4% Identity: 11% PDB header:protein binding Chain: B: PDB Molecule:tbib1; PDBTitle: tbib1 in complex with the tbia(beta) leader peptide Phyre2 PDB 2jd3 chain B Region: 63 - 90 Aligned: 28 Modelled: 28 Confidence: 10.2% Identity: 11% PDB header:dna binding protein Chain: B: PDB Molecule:stbb protein; PDBTitle: parr from plasmid pb171 Phyre2 1 c6c3rB_ 2 d2csua3 3 c3pvsA_ 4 c5uqdA_ 5 d2j9ga2 6 c1vjqB_ 7 c4rl6A_ 8 d1mkea1 9 d1yqga1 10 c2ekcA_ 11 c3g2bA_ 12 c5k9xA_ 13 c3ss4C_ 14 c6g2dC_ 15 c5dggB_ 16 c4inaA_ 17 c6jx3B_ 18 c2lweA_ 19 c5v1uB_ 20 c2jd3B_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56