1

.

.

.

.

.

.

.

.

10

.

.

.

.

.

.

.

.

.

20

.

.

.

.

.

.

.

.

.

30

.

.

.

.

.

.

.

.

.

40

.

.

.

.

.

.

.

.

.

50

.

.

.

.

.

.

.

.

.

60

Sequence

M

R

R

V

L

V

G

A

A

A

L

I

T

A

L

L

V

L

T

G

C

T

K

S

I

S

G

T

A

V

K

A

G

G

A

G

V

P

R

N

N

N

S

Q

E

R

Y

P

N

L

L

K

E

C

E

V

L

T

T

D

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

Disorder confidence

.

.

.

.

.

.

.

.

.

70

.

.

.

.

.

.

.

.

.

80

.

.

.

.

.

.

.

.

.

90

.

.

.

.

.

.

.

.

.

100

.

.

.

.

.

.

.

.

.

110

.

.

.

.

.

.

.

.

.

120

Sequence

I

L

A

K

T

V

G

A

D

P

L

D

I

Q

S

T

F

V

G

A

I

C

R

W

Q

A

A

N

P

A

G

L

I

D

I

T

R

F

W

F

E

Q

G

S

L

S

N

E

R

K

V

A

E

G

L

K

Y

Q

V

E

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

Disorder confidence

.

.

.

.

.

.

.

.

.

130

.

.

.

.

.

.

.

.

.

140

.

.

.

.

.

.

.

.

.

150

.

.

.

.

.

.

.

.

.

160

.

.

.

.

.

.

.

.

.

170

.

.

.

.

.

.

.

.

.

180

Sequence

T

R

A

I

Q

G

V

D

S

I

V

M

R

T

G

D

P

N

G

A

C

G

V

A

S

D

A

A

G

V

V

G

W

W

V

N

P

Q

A

P

G

I

D

A

C

G

Q

A

I

K

L

M

E

L

T

L

A

T

N

A

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

Disorder confidence

Sequence

Secondary structure

SS confidence

Disorder

Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 43%) Alpha helix ( 27%) Beta strand ( 23%)

Rank Aligned region

PDB 2i8g chain A domain 1 Region: 25 - 178 Aligned: 139 Modelled: 154 Confidence: 52.2% Identity: 16% Fold: Mog1p/PsbP-like Superfamily: Mog1p/PsbP-like Family: DIP2269-like Phyre2 PDB 2pxg chain A Region: 18 - 85 Aligned: 54 Modelled: 68 Confidence: 21.0% Identity: 17% PDB header:membrane protein Chain: A: PDB Molecule:outer membrane protein; PDBTitle: nmr solution structure of omla Phyre2 PDB 2b5i chain C domain 2 Region: 82 - 110 Aligned: 29 Modelled: 29 Confidence: 9.8% Identity: 21% Fold: Immunoglobulin-like beta-sandwich Superfamily: Fibronectin type III Family: Fibronectin type III Phyre2 PDB 2gys chain A domain 3 Region: 77 - 110 Aligned: 34 Modelled: 34 Confidence: 7.3% Identity: 29% Fold: Immunoglobulin-like beta-sandwich Superfamily: Fibronectin type III Family: Fibronectin type III Phyre2 PDB 2ca5 chain A domain 1 Region: 170 - 180 Aligned: 11 Modelled: 11 Confidence: 7.2% Identity: 64% Fold: Long alpha-hairpin Superfamily: MxiH-like Family: MxiH-like Phyre2 PDB 2n2h chain A Region: 56 - 66 Aligned: 11 Modelled: 11 Confidence: 6.8% Identity: 18% PDB header:transcription, protein binding Chain: A: PDB Molecule:sin3 histone deacetylase corepressor complex component PDBTitle: solution structure of sds3 in complex with sin3a Phyre2 PDB 1cc5 chain A Region: 49 - 66 Aligned: 18 Modelled: 18 Confidence: 5.9% Identity: 17% Fold: Cytochrome c Superfamily: Cytochrome c Family: monodomain cytochrome c Phyre2 PDB 5aon chain B Region: 38 - 70 Aligned: 33 Modelled: 33 Confidence: 5.4% Identity: 6% PDB header:signaling protein Chain: B: PDB Molecule:peroxin 14; PDBTitle: crystal structure of the conserved n-terminal domain of2 pex14 from trypanosoma brucei Phyre2 PDB 2mw3 chain A Region: 123 - 132 Aligned: 10 Modelled: 10 Confidence: 5.3% Identity: 20% PDB header:unknown function Chain: A: PDB Molecule:lasso peptide; PDBTitle: solution nmr structure of the lasso peptide streptomonomicin Phyre2 PDB 2xgl chain B Region: 54 - 69 Aligned: 16 Modelled: 16 Confidence: 5.2% Identity: 19% PDB header:antibiotic Chain: B: PDB Molecule:colicin-m immunity protein; PDBTitle: the x-ray structure of the escherichia coli colicin m immunity protein2 demonstrates the presence of a disulphide bridge, which is3 functionally essential Phyre2 1 d2i8ga1 2 c2pxgA_ 3 d2b5ic2 4 d2gysa3 5 d2ca5a1 6 c2n2hA_ 7 d1cc5a_ 8 c5aonB_ 9 c2mw3A_ 10 c2xglB_