1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	Q	I	A	F	V	A	Y	P	G	V	T	A	L	D	V	V	G	P	Y	E	V	L	R	N	L	P	H	A	Q	V	R	F	V	W	L	R	G	R	R	A	T	S	H	W	L	T	L	P	A	L	K	A	F	G	A	I	P	V
Secondary structure
SS confidence
Disorder		?	?															?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	D	E	R	I	V	H	Q	D	N	I	V	T	S	A	G	V	S	A	G	L	D	L	A	L	W	L	A	G	Q	L	G	G	E	A	R	A	K	A	I	Q	L	A	I	E	Y	D	P	Q	P	P	F	D	S	G	H	M	S	K	A
Secondary structure
SS confidence
Disorder																																																						?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.
Sequence		S	P	T	T	K	A	A	A	T	A	L	L	S	K	D	S	A	K	P	A	N	L	T	A	A	T	L	L	A	W	E	R	A	L	A	A	V	Q	S	R	R	R	K	R	Q	P	V	G	A	Q	A	R	R	P
Secondary structure
SS confidence
Disorder		?																?	?	?	?	?	?	?	?	?		?	?	?	?												?	?	?				?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 21%) Alpha helix ( 69%) Beta strand ( 7%)

Rank Aligned region

PDB 3ewn chain A Region: 2 - 144 Aligned: 142 Modelled: 143 Confidence: 100.0% Identity: 43% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:thij/pfpi family protein; PDBTitle: crystal structure of a thij/pfpi family protein from pseudomonas2 syringae Phyre2 PDB 3noo chain B Region: 3 - 164 Aligned: 149 Modelled: 150 Confidence: 100.0% Identity: 45% PDB header:lyase Chain: B: PDB Molecule:thij/pfpi family protein; PDBTitle: crystal structure of c101a isocyanide hydratase from pseudomonas2 fluorescens Phyre2 PDB 3bhn chain A Region: 3 - 150 Aligned: 136 Modelled: 148 Confidence: 99.9% Identity: 24% PDB header:unknown function Chain: A: PDB Molecule:thij/pfpi domain protein; PDBTitle: crystal structure of a dj-1/pfpi-like protein (shew_2856) from2 shewanella loihica pv-4 at 1.76 a resolution Phyre2 PDB 3mgk chain A Region: 3 - 119 Aligned: 117 Modelled: 117 Confidence: 99.9% Identity: 38% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:intracellular protease/amidase related enzyme (thij PDBTitle: crystal structure of probable protease/amidase from clostridium2 acetobutylicum atcc 824 Phyre2 PDB 3ot1 chain B Region: 2 - 117 Aligned: 114 Modelled: 116 Confidence: 99.9% Identity: 24% PDB header:structural genomics Chain: B: PDB Molecule:4-methyl-5(b-hydroxyethyl)-thiazole monophosphate PDBTitle: crystal structure of vc2308 protein Phyre2 PDB 3gra chain A Region: 2 - 104 Aligned: 103 Modelled: 103 Confidence: 99.9% Identity: 17% PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, arac family; PDBTitle: crystal structure of arac family transcriptional regulator from2 pseudomonas putida Phyre2 PDB 1p5f chain A Region: 2 - 106 Aligned: 104 Modelled: 104 Confidence: 99.9% Identity: 27% Fold: Flavodoxin-like Superfamily: Class I glutamine amidotransferase-like Family: DJ-1/PfpI Phyre2 PDB 4ge0 chain C Region: 3 - 106 Aligned: 102 Modelled: 103 Confidence: 99.9% Identity: 24% PDB header:unknown function Chain: C: PDB Molecule:uncharacterized protein c22e12.03c; PDBTitle: schizosaccharomyces pombe dj-1 t114p mutant Phyre2 PDB 3er6 chain D Region: 3 - 104 Aligned: 102 Modelled: 102 Confidence: 99.9% Identity: 17% PDB header:structural genomics, unknown function Chain: D: PDB Molecule:putative transcriptional regulator protein; PDBTitle: crystal structure of a putative transcriptional regulator protein from2 vibrio parahaemolyticus Phyre2 PDB 4e08 chain B Region: 2 - 107 Aligned: 104 Modelled: 105 Confidence: 99.9% Identity: 29% PDB header:motor protein Chain: B: PDB Molecule:dj-1 beta; PDBTitle: crystal structure of drosophila melanogaster dj-1beta Phyre2 PDB 4k2h chain G Region: 1 - 108 Aligned: 104 Modelled: 107 Confidence: 99.9% Identity: 35% PDB header:unknown function Chain: G: PDB Molecule:intracellular protease/amidase; PDBTitle: crystal structure of c103a mutant of dj-1 superfamily protein stm19312 from salmonella typhimurium Phyre2 PDB 2ab0 chain A domain 1 Region: 3 - 110 Aligned: 106 Modelled: 107 Confidence: 99.8% Identity: 25% Fold: Flavodoxin-like Superfamily: Class I glutamine amidotransferase-like Family: DJ-1/PfpI Phyre2 PDB 4xll chain B Region: 3 - 108 Aligned: 102 Modelled: 105 Confidence: 99.8% Identity: 31% PDB header:unknown function Chain: B: PDB Molecule:dj-1 family protein; PDBTitle: toxoplasma gondii dj-1, oxidized Phyre2 PDB 4y0n chain B Region: 2 - 95 Aligned: 92 Modelled: 93 Confidence: 99.8% Identity: 34% PDB header:hydrolase Chain: B: PDB Molecule:uncharacterized protein sav1875; PDBTitle: sav1875 Phyre2 PDB 2vrn chain A Region: 2 - 100 Aligned: 97 Modelled: 99 Confidence: 99.8% Identity: 27% PDB header:hydrolase Chain: A: PDB Molecule:protease i; PDBTitle: the structure of the stress response protein dr1199 from deinococcus2 radiodurans: a member of the dj-1 superfamily Phyre2 PDB 3f5d chain A Region: 1 - 106 Aligned: 105 Modelled: 106 Confidence: 99.8% Identity: 19% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:protein ydea; PDBTitle: crystal structure of a protein of unknown function from bacillus2 subtilis Phyre2 PDB 1oi4 chain A domain 1 Region: 2 - 91 Aligned: 89 Modelled: 90 Confidence: 99.8% Identity: 28% Fold: Flavodoxin-like Superfamily: Class I glutamine amidotransferase-like Family: DJ-1/PfpI Phyre2 PDB 2fex chain A domain 1 Region: 1 - 104 Aligned: 103 Modelled: 103 Confidence: 99.8% Identity: 27% Fold: Flavodoxin-like Superfamily: Class I glutamine amidotransferase-like Family: DJ-1/PfpI Phyre2 PDB 1g2i chain A Region: 2 - 91 Aligned: 88 Modelled: 89 Confidence: 99.8% Identity: 30% Fold: Flavodoxin-like Superfamily: Class I glutamine amidotransferase-like Family: DJ-1/PfpI Phyre2 PDB 3efe chain C Region: 2 - 106 Aligned: 103 Modelled: 105 Confidence: 99.7% Identity: 17% PDB header:chaperone Chain: C: PDB Molecule:thij/pfpi family protein; PDBTitle: the crystal structure of the thij/pfpi family protein from bacillus2 anthracis Phyre2 1 c3ewnA_ 2 c3nooB_ 3 c3bhnA_ 4 c3mgkA_ 5 c3ot1B_ 6 c3graA_ 7 d1p5fa_ 8 c4ge0C_ 9 c3er6D_ 10 c4e08B_ 11 c4k2hG_ 12 d2ab0a1 13 c4xllB_ 14 c4y0nB_ 15 c2vrnA_ 16 c3f5dA_ 17 d1oi4a1 18 d2fexa1 19 d1g2ia_ 20 c3efeC_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221