1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	R	R	R	G	R	R	A	W	A	G	R	M	F	V	A	P	N	L	A	A	V	V	V	F	M	L	F	P	L	G	F	S	L	Y	M	S	F	Q	K	W	D	L	F	T	H	A	T	F	V	R	L	D	N	F	R	N	L	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	S	D	P	L	F	L	I	A	V	V	N	T	A	V	Y	T	V	G	T	V	V	P	T	V	I	V	S	L	V	V	A	A	F	L	N	R	K	I	K	G	I	S	L	F	R	T	V	V	F	L	P	L	A	I	S	S	V	V	M
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	V	V	W	Q	F	V	F	N	T	D	N	G	L	L	N	I	M	L	G	W	L	G	I	G	P	I	P	W	L	I	E	P	R	W	A	M	V	S	L	C	L	V	S	V	W	R	S	V	P	F	A	T	V	V	L	L	A	A	M
Secondary structure
SS confidence
Disorder																													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Q	G	V	P	E	T	V	Y	E	A	A	R	I	D	G	A	G	E	I	R	Q	F	V	S	I	T	V	P	L	I	R	G	A	L	S	F	V	V	V	I	S	I	I	H	A	F	Q	A	F	D	L	V	Y	V	L	T	G	A	N	G
Secondary structure
SS confidence
Disorder																																																													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		G	P	E	T	A	T	Y	V	L	G	I	M	L	F	Q	H	A	F	S	F	L	E	F	G	Y	A	S	A	L	A	W	V	M	F	A	I	L	L	V	L	T	V	L	Q	L	R	I	T	H	R	R	S	W	E	A	S	R	G	L	G
Secondary structure
SS confidence
Disorder			?																																															?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
Sequence
Secondary structure
SS confidence
Disorder
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 8%) Alpha helix ( 75%) Beta strand ( 1%) TM helix ( 48%) (View membrane topology prediction)

Rank Aligned region

PDB 3fh6 chain F Region: 7 - 293 Aligned: 286 Modelled: 287 Confidence: 100.0% Identity: 28% PDB header:transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: crystal structure of the resting state maltose transporter from e.2 coli Phyre2 PDB 4tqv chain I Region: 3 - 293 Aligned: 281 Modelled: 282 Confidence: 100.0% Identity: 21% PDB header:transport protein Chain: I: PDB Molecule:algm1; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 2r6g chain F Region: 48 - 283 Aligned: 236 Modelled: 236 Confidence: 100.0% Identity: 29% PDB header:hydrolase/transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: the crystal structure of the e. coli maltose transporter Phyre2 PDB 2r6g chain G domain 1 Region: 7 - 298 Aligned: 273 Modelled: 277 Confidence: 100.0% Identity: 15% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2r6g chain F domain 2 Region: 53 - 283 Aligned: 231 Modelled: 231 Confidence: 100.0% Identity: 30% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 4tqv chain J Region: 5 - 294 Aligned: 265 Modelled: 266 Confidence: 100.0% Identity: 17% PDB header:transport protein Chain: J: PDB Molecule:algm2; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 2onk chain C domain 1 Region: 9 - 288 Aligned: 249 Modelled: 262 Confidence: 100.0% Identity: 20% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2onk chain C Region: 9 - 288 Aligned: 249 Modelled: 262 Confidence: 100.0% Identity: 20% PDB header:membrane protein Chain: C: PDB Molecule:molybdate/tungstate abc transporter, permease PDBTitle: abc transporter modbc in complex with its binding protein2 moda Phyre2 PDB 3d31 chain C domain 1 Region: 14 - 285 Aligned: 244 Modelled: 262 Confidence: 100.0% Identity: 16% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 3d31 chain D Region: 14 - 285 Aligned: 244 Modelled: 262 Confidence: 100.0% Identity: 16% PDB header:transport protein Chain: D: PDB Molecule:sulfate/molybdate abc transporter, permease protein; PDBTitle: modbc from methanosarcina acetivorans Phyre2 PDB 4ymu chain C Region: 55 - 292 Aligned: 211 Modelled: 218 Confidence: 100.0% Identity: 15% PDB header:protein binding/transport protein Chain: C: PDB Molecule:abc-type amino acid transport system, permease component; PDBTitle: crystal structure of an amino acid abc transporter complex with2 arginines and atps Phyre2 PDB 3dhw chain A domain 1 Region: 66 - 283 Aligned: 197 Modelled: 209 Confidence: 99.9% Identity: 15% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2r6g chain F domain 1 Region: 7 - 50 Aligned: 44 Modelled: 44 Confidence: 95.0% Identity: 27% Fold: MalF N-terminal region-like Superfamily: MalF N-terminal region-like Family: MalF N-terminal region-like Phyre2 PDB 5kbu chain A Region: 70 - 275 Aligned: 143 Modelled: 143 Confidence: 88.3% Identity: 15% PDB header:transport protein Chain: A: PDB Molecule:glutamate receptor 2,voltage-dependent calcium channel PDBTitle: cryo-em structure of glua2-2xstz complex at 7.8 angstrom resolution Phyre2 PDB 2m8g chain X Region: 175 - 205 Aligned: 31 Modelled: 31 Confidence: 40.3% Identity: 16% PDB header:transcription Chain: X: PDB Molecule:transcriptional regulator; PDBTitle: structure, function, and tethering of dna-binding domains in 542 transcriptional activators Phyre2 PDB 4l5e chain A Region: 175 - 205 Aligned: 31 Modelled: 31 Confidence: 39.2% Identity: 13% PDB header:protein binding Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: crystal structure of a. aeolicus ntrc1 dna binding domain Phyre2 PDB 1umq chain A Region: 175 - 205 Aligned: 31 Modelled: 31 Confidence: 36.7% Identity: 13% PDB header:dna-binding protein Chain: A: PDB Molecule:photosynthetic apparatus regulatory protein; PDBTitle: solution structure and dna binding of the effector domain2 from the global regulator prra(rega) from r. sphaeroides:3 insights into dna binding specificity Phyre2 PDB 1umq chain A Region: 175 - 205 Aligned: 31 Modelled: 31 Confidence: 36.7% Identity: 13% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 1fip chain A Region: 175 - 205 Aligned: 31 Modelled: 31 Confidence: 30.4% Identity: 19% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 1ntc chain A Region: 175 - 205 Aligned: 31 Modelled: 31 Confidence: 30.1% Identity: 26% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 1 c3fh6F_ 2 c4tqvI_ 3 c2r6gF_ 4 d2r6gg1 5 d2r6gf2 6 c4tqvJ_ 7 d2onkc1 8 c2onkC_ 9 d3d31c1 10 c3d31D_ 11 c4ymuC_ 12 d3dhwa1 13 d2r6gf1 14 c5kbuA_ 15 c2m8gX_ 16 c4l5eA_ 17 c1umqA_ 18 d1umqa_ 19 d1fipa_ 20 d1ntca_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39