Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD2133c_(-)_2393859_2394647
DateMon Aug 5 13:25:25 BST 2019
Unique Job IDd0bd69213e5f004a
SequenceVLADGELTVL ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:52.818 Y:64.834 Z:38.147
Model (left) based on template c4hndB_
Top template information
PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 4-kinase type 2-alpha;
PDBTitle: crystal structure of the catalytic domain of selenomethionine2 substituted human pi4kiialpha in complex with adp
Confidence and coverage
Confidence:100.0% Coverage: 85%
223 residues ( 85% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
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Sequence analysis 

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#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c4hndB_
100.0 19
PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 4-kinase type 2-alpha;
PDBTitle: crystal structure of the catalytic domain of selenomethionine2 substituted human pi4kiialpha in complex with adp
2c4plaA_
100.0 19
PDB header:transferase,hydrolase
Chain: A: PDB Molecule:chimera protein of phosphatidylinositol 4-kinase type 2-
PDBTitle: crystal structure of phosphatidyl inositol 4-kinase ii alpha in2 complex with atp
3c5xomB_
99.7 16
PDB header:transferase
Chain: B: PDB Molecule:glycosaminoglycan xylosylkinase;
PDBTitle: hydra fam20
4c5yh0G_
99.7 18
PDB header:transferase
Chain: G: PDB Molecule:drfam20c1;
PDBTitle: the structure of drfam20c1
5c5wrrA_
99.7 21
PDB header:transferase
Chain: A: PDB Molecule:pseudokinase fam20a;
PDBTitle: crystal structure of fam20a
6c4kqaC_
99.6 17
PDB header:transferase
Chain: C: PDB Molecule:protein h03a11.1;
PDBTitle: crystal structure of the golgi casein kinase
7c5dfzC_
99.3 17
PDB header:transferase
Chain: C: PDB Molecule:phosphatidylinositol 3-kinase vps34;
PDBTitle: structure of vps34 complex ii from s. cerevisiae.
8c2y3aA_
99.2 13
PDB header:transferase
Chain: A: PDB Molecule:phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and the2 drug gdc-0941
9c5dxuA_
99.1 13
PDB header:transferase/inhibitor
Chain: A: PDB Molecule:phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic
PDBTitle: p110delta/p85alpha with gdc-0326
10c4d0mW_
99.1 16
PDB header:signaling protein
Chain: W: PDB Molecule:phosphatidylinositol 4-kinase beta;
PDBTitle: phosphatidylinositol 4-kinase iii beta in a complex with rab11a-gtp-2 gamma-s and the rab-binding domain of fip3
11c2wxoA_
99.0 12
PDB header:transferase
Chain: A: PDB Molecule:phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic
PDBTitle: the crystal structure of the murine class ia pi 3-kinase p110delta in2 complex with as5.
12c3ls8A_
99.0 15
PDB header:transferase
Chain: A: PDB Molecule:phosphatidylinositol 3-kinase catalytic subunit
PDBTitle: crystal structure of human pik3c3 in complex with 3-[4-(4-2 morpholinyl)thieno[3,2-d]pyrimidin-2-yl]-phenol
13c5is5A_
99.0 14
PDB header:transferase
Chain: A: PDB Molecule:phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic
PDBTitle: discovery and pharmacological characterization of novel quinazoline-2 based pi3k delta-selective inhibitors
14c2x6kB_
99.0 18
PDB header:transferase
Chain: B: PDB Molecule:phosphotidylinositol 3 kinase 59f;
PDBTitle: the crystal structure of the drosophila class iii pi3-kinase vps34 in2 complex with pi-103
15c4yknA_
98.9 17
PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit alpha,
PDBTitle: pi3k alpha lipid kinase with active site inhibitor
16c6bq1A_
98.8 15
PDB header:transferase/signaling protein
Chain: A: PDB Molecule:phosphatidylinositol 4-kinase iii alpha (pi4ka);
PDBTitle: human pi4kiiia lipid kinase complex
17c6bq1E_
98.8 15
PDB header:transferase/signaling protein
Chain: E: PDB Molecule:phosphatidylinositol 4-kinase iii alpha (pi4ka);
PDBTitle: human pi4kiiia lipid kinase complex
18c2rd0A_
98.8 18
PDB header:transferase/oncoprotein
Chain: A: PDB Molecule:phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic
PDBTitle: structure of a human p110alpha/p85alpha complex
19c3akjB_
98.5 18
PDB header:transferase
Chain: B: PDB Molecule:ctka;
PDBTitle: crystal structure of a helicobacter pylori proinflammatory kinase ctka
20d1e7ua4
98.4 14
Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Phoshoinositide 3-kinase (PI3K), catalytic domain
21c1e8zA_
not modelled 98.4 17
PDB header:transferase
Chain: A: PDB Molecule:phosphatidylinositol 3-kinase catalytic subunit;
PDBTitle: structure determinants of phosphoinositide 3-kinase2 inhibition by wortmannin, ly294002, quercetin, myricetin3 and staurosporine
22c4jspA_
not modelled 97.4 16
PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase mtor;
PDBTitle: structure of mtordeltan-mlst8-atpgammas-mg complex
23c6jxaA_
not modelled 96.8 14
PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase tel1;
PDBTitle: tel1 kinase compact monomer
24c3dntB_
not modelled 96.8 14
PDB header:transferase
Chain: B: PDB Molecule:protein hipa;
PDBTitle: structures of mdt proteins
25c5h64a_
not modelled 96.6 16
PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase mtor;
PDBTitle: cryo-em structure of mtorc1
26c5yz0A_
not modelled 96.1 17
PDB header:cell cycle
Chain: A: PDB Molecule:serine/threonine-protein kinase atr;
PDBTitle: cryo-em structure of human atr-atrip complex
27c5np1A_
not modelled 96.1 13
PDB header:transferase
Chain: A: PDB Molecule:serine-protein kinase atm;
PDBTitle: open protomer of human atm (ataxia telangiectasia mutated)
28c6emkA_
not modelled 96.1 26
PDB header:signaling protein
Chain: A: PDB Molecule:serine/threonine-protein kinase tor2;
PDBTitle: cryo-em structure of saccharomyces cerevisiae target of rapamycin2 complex 2
29c5np0A_
not modelled 96.0 13
PDB header:signaling protein
Chain: A: PDB Molecule:serine-protein kinase atm;
PDBTitle: closed dimer of human atm (ataxia telangiectasia mutated)
30c5fvmB_
not modelled 96.0 26
PDB header:transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase tor2;
PDBTitle: cryo electron microscopy of a complex of tor and lst8
31c5zcsB_
not modelled 95.9 21
PDB header:gene regulation
Chain: B: PDB Molecule:serine/threonine-protein kinase mtor;
PDBTitle: 4.9 angstrom cryo-em structure of human mtor complex 2
32c5x6oC_
not modelled 95.8 19
PDB header:transferase/dna binding protein
Chain: C: PDB Molecule:serine/threonine-protein kinase mec1;
PDBTitle: intact atr/mec1-atrip/ddc2 complex
33c4pu5A_
not modelled 95.6 18
PDB header:toxin
Chain: A: PDB Molecule:toxin-antitoxin system toxin hipa family;
PDBTitle: shewanella oneidensis toxin antitoxin system toxin protein hipa bound2 with amppnp and mg
34c5luqA_
not modelled 95.3 18
PDB header:transferase
Chain: A: PDB Molecule:dna-dependent protein kinase catalytic subunit,dna-
PDBTitle: crystal structure of human dna-dependent protein kinase catalytic2 subunit (dna-pkcs)
35c5luqB_
not modelled 95.3 18
PDB header:transferase
Chain: B: PDB Molecule:dna-dependent protein kinase catalytic subunit,dna-
PDBTitle: crystal structure of human dna-dependent protein kinase catalytic2 subunit (dna-pkcs)
36d1cjaa_
not modelled 94.8 21
Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Actin-fragmin kinase, catalytic domain
37c6ig9T_
not modelled 94.7 8
PDB header:transcription
Chain: T: PDB Molecule:transcription-associated protein 1;
PDBTitle: tra1 subunit from saccharomyces cerevisiae saga complex
38c5oejB_
not modelled 94.2 8
PDB header:transcription
Chain: B: PDB Molecule:tra1 subunit within the chromatin modifying complex saga;
PDBTitle: structure of tra1 subunit within the chromatin modifying complex saga
39c5ojsT_
not modelled 93.4 8
PDB header:transcription
Chain: T: PDB Molecule:transcription-associated protein 1;
PDBTitle: cryo-em structure of the saga and nua4 coactivator subunit tra1
40c5w1rA_
not modelled 93.3 18
PDB header:dna binding protein
Chain: A: PDB Molecule:dna-dependent protein kinase catalytic subunit;
PDBTitle: cryo-em structure of dnapkcs
41c5yk2A_
not modelled 92.9 15
PDB header:transport protein
Chain: A: PDB Molecule:probable conserved atp-binding protein abc transporter;
PDBTitle: the complex structure of rv3197-erythromycin from mycobacterium2 tuberculosis
42c4pedA_
not modelled 92.2 16
PDB header:transferase
Chain: A: PDB Molecule:chaperone activity of bc1 complex-like, mitochondrial;
PDBTitle: mitochondrial adck3 employs an atypical protein kinase-like fold to2 enable coenzyme q biosynthes
43d1zara2
not modelled 89.4 11
Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:RIO1-like kinases
44c4r77A_
not modelled 88.6 9
PDB header:transferase
Chain: A: PDB Molecule:choline kinase;
PDBTitle: crystal structure of choline kinase lica from streptococcus pneumoniae
45c6g51v_
not modelled 75.1 7
PDB header:ribosome
Chain: V: PDB Molecule:40s ribosomal protein s21;
PDBTitle: cryo-em structure of a late human pre-40s ribosomal subunit - state d
46c6fdnA_
not modelled 74.7 9
PDB header:nuclear protein
Chain: A: PDB Molecule:serine/threonine-protein kinase rio2;
PDBTitle: rio2 structure
47c4o96D_
not modelled 66.3 13
PDB header:hydrolase
Chain: D: PDB Molecule:type iii effector protein kinase;
PDBTitle: 2.60 angstrom resolution crystal structure of a protein kinase domain2 of type iii effector nleh2 (ecs1814) from escherichia coli o157:h73 str. sakai
48c3dxqB_
not modelled 66.2 14
PDB header:transferase
Chain: B: PDB Molecule:choline/ethanolamine kinase family protein;
PDBTitle: crystal structure of choline/ethanolamine kinase family protein2 (np_106042.1) from mesorhizobium loti at 2.55 a resolution
49d2o3bb1
not modelled 62.4 19
Fold:Nuclease A inhibitor (NuiA)
Superfamily:Nuclease A inhibitor (NuiA)
Family:Nuclease A inhibitor (NuiA)
50c3byvA_
not modelled 58.1 11
PDB header:transferase
Chain: A: PDB Molecule:rhoptry kinase;
PDBTitle: crystal structure of toxoplasma gondii specific rhoptry2 antigen kinase domain
51c3dxpA_
not modelled 57.0 14
PDB header:transferase
Chain: A: PDB Molecule:putative acyl-coa dehydrogenase;
PDBTitle: crystal structure of a putative aminoglycoside phosphotransferase2 (reut_a1007) from ralstonia eutropha jmp134 at 2.32 a resolution
52c5igwA_
not modelled 54.0 13
PDB header:transferase
Chain: A: PDB Molecule:macrolide 2'-phosphotransferase ii;
PDBTitle: macrolide 2'-phosphotransferase type ii - complex with gdp and2 clarithromycin
53c5jd9A_
not modelled 54.0 9
PDB header:structural protein
Chain: A: PDB Molecule:spore coat protein h;
PDBTitle: bacillus cereus coth kinase
54c4gygA_
not modelled 51.7 12
PDB header:transferase
Chain: A: PDB Molecule:rio2 kinase;
PDBTitle: crystal structure of the rio2 kinase from chaetomium thermophilum
55c5nclA_
not modelled 50.4 35
PDB header:signaling protein
Chain: A: PDB Molecule:serine/threonine-protein kinase cbk1;
PDBTitle: crystal structure of the cbk1-mob2 kinase-coactivator complex with an2 ssd1 peptide
56c4bvuA_
not modelled 50.3 19
PDB header:transferase/ligase/protein binding
Chain: A: PDB Molecule:protein kinase ospg;
PDBTitle: structure of shigella effector ospg in complex with host ubch5c-2 ubiquitin conjugate
57c2pziA_
not modelled 50.1 17
PDB header:transferase
Chain: A: PDB Molecule:probable serine/threonine-protein kinase pkng;
PDBTitle: crystal structure of protein kinase pkng from mycobacterium2 tuberculosis in complex with tetrahydrobenzothiophene ax20017
58c4ockA_
not modelled 48.2 17
PDB header:transferase
Chain: A: PDB Molecule:n-acetylhexosamine 1-phosphate kinase;
PDBTitle: n-acetylhexosamine 1-phosphate kinase in complex with glcnac and2 amppnp
59c3i0oA_
not modelled 47.8 13
PDB header:transferase
Chain: A: PDB Molecule:spectinomycin phosphotransferase;
PDBTitle: crystal structure of spectinomycin phosphotransferase,2 aph(9)-ia, in complex with adp and spectinomcyin
60c3r78B_
not modelled 44.3 4
PDB header:transferase
Chain: B: PDB Molecule:aminoglycoside 3'-phosphotransferase apha1-iab;
PDBTitle: crystal structure of the aminoglycoside phosphotransferase aph(3')-ia,2 atp-bound
61c6m7zE_
not modelled 43.7 10
PDB header:transferase
Chain: E: PDB Molecule:bradyzoite pseudokinase 1;
PDBTitle: a divergent kinase lacking the glycine-rich loop regulates membrane2 ultrastructure of the toxoplasma parasitophorous vacuole
62c4azwA_
not modelled 43.5 13
PDB header:transferase
Chain: A: PDB Molecule:wbdd;
PDBTitle: crystal structure of monomeric wbdd.
63c4jrnA_
not modelled 43.0 30
PDB header:transferase
Chain: A: PDB Molecule:rhoptry kinase family protein;
PDBTitle: rop18 kinase domain in complex with amp-pnp and sucrose
64c5igrA_
not modelled 41.9 15
PDB header:transferase/antibiotic
Chain: A: PDB Molecule:macrolide 2'-phosphotransferase;
PDBTitle: macrolide 2'-phosphotransferase type i - complex with gdp and2 oleandomycin
65c1tqmA_
not modelled 41.3 19
PDB header:ribosome
Chain: A: PDB Molecule:conserved hypothetical protein;
PDBTitle: crystal structure of a. fulgidus rio2 serine protein kinase bound to2 amppnp
66c4w9xA_
not modelled 41.2 15
PDB header:transferase
Chain: A: PDB Molecule:bmp-2-inducible protein kinase;
PDBTitle: crystal structure of bmp-2-inducible kinase in complex with2 baricitinib
67c4azsA_
not modelled 40.8 13
PDB header:transferase
Chain: A: PDB Molecule:methyltransferase wbdd;
PDBTitle: high resolution (2.2 a) crystal structure of wbdd.
68c3dzoA_
not modelled 39.2 11
PDB header:transferase
Chain: A: PDB Molecule:rhoptry kinase domain;
PDBTitle: crystal structure of a rhoptry kinase from toxoplasma gondii
69c3f2rA_
not modelled 36.8 20
PDB header:transferase
Chain: A: PDB Molecule:choline kinase alpha;
PDBTitle: crystal structure of human choline kinase alpha in complex with2 hemicholinium-3
70c4cdsA_
not modelled 36.5 16
PDB header:transferase
Chain: A: PDB Molecule:tyrosine kinase as - a common ancestor of src and abl;
PDBTitle: tyrosine kinase as - a common ancestor of src and abl
71c3q3wB_
not modelled 36.0 19
PDB header:transferase
Chain: B: PDB Molecule:3-isopropylmalate dehydratase small subunit;
PDBTitle: isopropylmalate isomerase small subunit from campylobacter jejuni.
72d1j7la_
not modelled 35.6 13
Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:APH phosphotransferases
73c3en9B_
not modelled 35.4 24
PDB header:hydrolase
Chain: B: PDB Molecule:o-sialoglycoprotein endopeptidase/protein kinase;
PDBTitle: structure of the methanococcus jannaschii kae1-bud32 fusion2 protein
74c5dfzB_
not modelled 34.9 11
PDB header:transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase vps15;
PDBTitle: structure of vps34 complex ii from s. cerevisiae.
75c3c5iD_
not modelled 34.8 8
PDB header:transferase
Chain: D: PDB Molecule:choline kinase;
PDBTitle: crystal structure of plasmodium knowlesi choline kinase, pkh_134520
76c1zp9A_
not modelled 34.7 22
PDB header:transferase
Chain: A: PDB Molecule:rio1 kinase;
PDBTitle: crystal structure of full-legnth a.fulgidus rio1 serine kinase bound2 to atp and mn2+ ions.
77c3pfqA_
not modelled 34.0 26
PDB header:transferase
Chain: A: PDB Molecule:protein kinase c beta type;
PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii
78c6fucA_
not modelled 33.9 19
PDB header:transferase
Chain: A: PDB Molecule:aminoglycoside phosphotransferase;
PDBTitle: structure of aminoglycoside phosphotransferase aph(3'')-id from2 streptomyces rimosus atcc10970
79c2q83A_
not modelled 33.0 25
PDB header:transferase
Chain: A: PDB Molecule:ytaa protein;
PDBTitle: crystal structure of ytaa (2635576) from bacillus subtilis at 2.50 a2 resolution
80c4pdyA_
not modelled 32.3 25
PDB header:transferase
Chain: A: PDB Molecule:aminoglycoside phosphotransferase;
PDBTitle: crystal structure of aminoglycoside phosphotransferase from2 alicyclobacillus acidocaldarius subsp. acidocaldarius dsm 446
81c4ci6B_
not modelled 31.9 30
PDB header:transferase/structural protein
Chain: B: PDB Molecule:protein kinase yopo;
PDBTitle: mechanisms of crippling actin-dependent phagocytosis by yopo
82c1ym7C_
not modelled 31.9 39
PDB header:transferase
Chain: C: PDB Molecule:beta-adrenergic receptor kinase 1;
PDBTitle: g protein-coupled receptor kinase 2 (grk2)
83c5clrB_
not modelled 31.4 33
PDB header:transferase
Chain: B: PDB Molecule:legk4;
PDBTitle: crystal structure of legk4_apo kinase
84c3c4yA_
not modelled 31.0 37
PDB header:transferase
Chain: A: PDB Molecule:rhodopsin kinase;
PDBTitle: crystal structure of apo form of g protein coupled receptor kinase 12 at 7.51a
85c3epsB_
not modelled 30.6 17
PDB header:transferase, hydrolase
Chain: B: PDB Molecule:isocitrate dehydrogenase kinase/phosphatase;
PDBTitle: the crystal structure of isocitrate dehydrogenase kinase/phosphatase2 from e. coli
86c3korD_
not modelled 30.4 22
PDB header:transcription
Chain: D: PDB Molecule:possible trp repressor;
PDBTitle: crystal structure of a putative trp repressor from staphylococcus2 aureus
87c3f2rB_
not modelled 30.3 20
PDB header:transferase
Chain: B: PDB Molecule:choline kinase alpha;
PDBTitle: crystal structure of human choline kinase alpha in complex with2 hemicholinium-3
88c4oauC_
not modelled 29.0 17
PDB header:hydrolase/rna
Chain: C: PDB Molecule:2-5a-dependent ribonuclease;
PDBTitle: complete human rnase l in complex with biological activators.
89c3tkuB_
not modelled 28.7 26
PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:serine/threonine-protein kinase mrck beta;
PDBTitle: mrck beta in complex with fasudil
90c3ckxA_
not modelled 28.6 15
PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase 24;
PDBTitle: crystal structure of sterile 20-like kinase 3 (mst3, stk24) in complex2 with staurosporine
91d2ppqa1
not modelled 28.0 13
Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:APH phosphotransferases
92c3frwF_
not modelled 27.1 14
PDB header:structural genomics, unknown function
Chain: F: PDB Molecule:putative trp repressor protein;
PDBTitle: crystal structure of putative trpr protein from ruminococcus obeum
93d1nd4a_
not modelled 26.2 13
Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:APH phosphotransferases
94c4ww7A_
not modelled 25.5 26
PDB header:transferase
Chain: A: PDB Molecule:ekc/keops complex subunit bud32;
PDBTitle: crystal structure of binary complex bud32-cgi121 in complex with amp
95c3gndC_
not modelled 25.2 29
PDB header:lyase
Chain: C: PDB Molecule:aldolase lsrf;
PDBTitle: crystal structure of e. coli lsrf in complex with ribulose-5-phosphate
96c3nyoB_
not modelled 23.8 33
PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein-coupled receptor kinase 6 in complex2 with amp
97c3qa8A_
not modelled 23.6 26
PDB header:immune system, signaling protein
Chain: A: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta
98c2hcuA_
not modelled 21.7 24
PDB header:lyase
Chain: A: PDB Molecule:3-isopropylmalate dehydratase small subunit;
PDBTitle: crystal structure of smu.1381 (or leud) from streptococcus mutans
99c4xpuA_
not modelled 21.6 22
PDB header:hydrolase
Chain: A: PDB Molecule:endonuclease v;
PDBTitle: the crystal structure of endov from e.coli
100c5ckwA_
not modelled 21.4 39
PDB header:transferase
Chain: A: PDB Molecule:legk4;
PDBTitle: crystal structure of legk4_amppnp kinase
101c2pkpA_
not modelled 21.3 24
PDB header:lyase
Chain: A: PDB Molecule:homoaconitase small subunit;
PDBTitle: crystal structure of 3-isopropylmalate dehydratase (leud)2 from methhanocaldococcus jannaschii dsm2661 (mj1271)
102c5uxbA_
not modelled 20.7 15
PDB header:transferase
Chain: A: PDB Molecule:macrolide 2'-phosphotransferase mphh;
PDBTitle: crystal structure of macrolide 2'-phosphotransferase mphh from2 brachybacterium faecium, apoenzyme
103c2ckpB_
not modelled 20.3 21
PDB header:transferase
Chain: B: PDB Molecule:choline kinase alpha;
PDBTitle: crystal structure of human choline kinase alpha-2 in2 complex with adp

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