1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	G	P	A	I	D	A	S	P	A	L	T	F	N	Q	S	S	A	S	I	Q	Q	R	R	L	S	T	G	R	Q	M	W	V	L	Y	R	R	F	A	A	P	S	L	L	N	G	E	V	L	T	T	V	G	A	P	I	I	F	M
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	G	F	Y	I	P	F	A	I	P	W	N	Q	F	V	G	G	A	S	S	G	V	A	S	N	L	G	Q	Y	I	T	P	L	V	T	L	Q	A	V	S	F	A	A	I	G	S	G	F	R	A	A	T	D	S	L	L	G	V	N	R
Secondary structure
SS confidence
Disorder									?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	F	Q	S	M	P	M	A	P	L	T	P	L	L	A	R	V	W	V	A	V	D	R	C	F	T	G	L	V	I	S	L	V	C	G	Y	V	I	G	F	R	F	H	R	G	A	L	Y	I	V	G	F	C	L	L	V	I	A	I	G
Secondary structure
SS confidence
Disorder						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	V	L	S	F	A	A	D	L	V	G	T	V	T	R	N	P	D	A	M	L	P	L	L	S	L	P	I	L	I	F	G	L	L	S	I	G	L	M	P	L	K	L	F	P	H	W	I	H	P	F	V	R	N	Q	P	I	S	Q	F
Secondary structure
SS confidence
Disorder															?	?																					?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.
Sequence		V	A	A	L	R	A	L	A	G	D	T	T	K	T	A	S	Q	V	S	W	P	V	M	A	P	T	L	T	W	L	F	A	F	V	V	I	L	A	L	S	S	T	I	V	L	A	R	R	P
Secondary structure
SS confidence
Disorder															?	?																														?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 20%) Alpha helix ( 75%) Beta strand ( 0%) TM helix ( 47%) (View membrane topology prediction)

Rank Aligned region

PDB 6an7 chain C Region: 29 - 288 Aligned: 239 Modelled: 260 Confidence: 100.0% Identity: 10% PDB header:transport protein Chain: C: PDB Molecule:transport permease protein; PDBTitle: crystal structure of o-antigen polysaccharide abc-transporter Phyre2 PDB 6an7 chain D Region: 29 - 288 Aligned: 237 Modelled: 260 Confidence: 100.0% Identity: 10% PDB header:transport protein Chain: D: PDB Molecule:transport permease protein; PDBTitle: crystal structure of o-antigen polysaccharide abc-transporter Phyre2 PDB 5njg chain B Region: 27 - 288 Aligned: 253 Modelled: 262 Confidence: 100.0% Identity: 12% PDB header:transport protein Chain: B: PDB Molecule:atp-binding cassette sub-family g member 2; PDBTitle: structure of an abc transporter: part of the structure that could be2 built de novo Phyre2 PDB 5nj3 chain B Region: 8 - 288 Aligned: 271 Modelled: 281 Confidence: 100.0% Identity: 11% PDB header:transport protein Chain: B: PDB Molecule:atp-binding cassette sub-family g member 2; PDBTitle: structure of an abc transporter: complete structure Phyre2 PDB 5do7 chain B Region: 22 - 288 Aligned: 258 Modelled: 267 Confidence: 100.0% Identity: 9% PDB header:transport protein Chain: B: PDB Molecule:atp-binding cassette sub-family g member 8; PDBTitle: crystal structure of the human sterol transporter abcg5/abcg8 Phyre2 PDB 5do7 chain A Region: 12 - 288 Aligned: 269 Modelled: 277 Confidence: 100.0% Identity: 12% PDB header:transport protein Chain: A: PDB Molecule:atp-binding cassette sub-family g member 5; PDBTitle: crystal structure of the human sterol transporter abcg5/abcg8 Phyre2 PDB 5xjy chain A Region: 80 - 289 Aligned: 201 Modelled: 210 Confidence: 99.2% Identity: 6% PDB header:transport protein Chain: A: PDB Molecule:atp-binding cassette sub-family a member 1; PDBTitle: cryo-em structure of human abca1 Phyre2 PDB 5gas chain N Region: 46 - 235 Aligned: 190 Modelled: 190 Confidence: 45.1% Identity: 10% PDB header:hydrolase Chain: N: PDB Molecule:archaeal/vacuolar-type h+-atpase subunit i; PDBTitle: thermus thermophilus v/a-atpase, conformation 2 Phyre2 PDB 5ir6 chain B Region: 31 - 287 Aligned: 225 Modelled: 237 Confidence: 12.1% Identity: 8% PDB header:oxidoreductase Chain: B: PDB Molecule:bd-type quinol oxidase subunit ii; PDBTitle: the structure of bd oxidase from geobacillus thermodenitrificans Phyre2 PDB 3cqy chain A Region: 1 - 8 Aligned: 8 Modelled: 2 Confidence: 11.4% Identity: 38% PDB header:transferase Chain: A: PDB Molecule:anhydro-n-acetylmuramic acid kinase; PDBTitle: crystal structure of a functionally unknown protein (so_1313) from2 shewanella oneidensis mr-1 Phyre2 PDB 4yh5 chain B Region: 1 - 7 Aligned: 7 Modelled: 7 Confidence: 10.2% Identity: 43% PDB header:transferase Chain: B: PDB Molecule:levoglucosan kinase; PDBTitle: lipomyces starkeyi levoglucosan kinase bound to adp and manganese Phyre2 PDB 5n9y chain B Region: 222 - 288 Aligned: 64 Modelled: 67 Confidence: 9.7% Identity: 13% PDB header:membrane protein Chain: B: PDB Molecule:zinc transport protein zntb; PDBTitle: the full-length structure of zntb Phyre2 PDB 3rko chain F Region: 37 - 117 Aligned: 81 Modelled: 81 Confidence: 8.4% Identity: 11% PDB header:oxidoreductase Chain: F: PDB Molecule:nadh-quinone oxidoreductase subunit j; PDBTitle: crystal structure of the membrane domain of respiratory complex i from2 e. coli at 3.0 angstrom resolution Phyre2 PDB 2k9y chain A Region: 251 - 288 Aligned: 38 Modelled: 38 Confidence: 7.9% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:ephrin type-a receptor 2; PDBTitle: epha2 dimeric structure in the lipidic bicelle at ph 5.0 Phyre2 PDB 2k9y chain B Region: 251 - 288 Aligned: 38 Modelled: 38 Confidence: 7.9% Identity: 13% PDB header:transferase Chain: B: PDB Molecule:ephrin type-a receptor 2; PDBTitle: epha2 dimeric structure in the lipidic bicelle at ph 5.0 Phyre2 PDB 2x7l chain P Region: 8 - 40 Aligned: 33 Modelled: 33 Confidence: 7.3% Identity: 21% PDB header:immune system Chain: P: PDB Molecule:protein rev; PDBTitle: implications of the hiv-1 rev dimer structure at 3.2a resolution for2 multimeric binding to the rev response element Phyre2 PDB 3lph chain D Region: 8 - 40 Aligned: 33 Modelled: 33 Confidence: 6.1% Identity: 21% PDB header:viral protein Chain: D: PDB Molecule:protein rev; PDBTitle: crystal structure of the hiv-1 rev dimer Phyre2 PDB 5ir6 chain A Region: 79 - 288 Aligned: 203 Modelled: 210 Confidence: 5.1% Identity: 16% PDB header:oxidoreductase Chain: A: PDB Molecule:bd-type quinol oxidase subunit i; PDBTitle: the structure of bd oxidase from geobacillus thermodenitrificans Phyre2 1 c6an7C_ 2 c6an7D_ 3 c5njgB_ 4 c5nj3B_ 5 c5do7B_ 6 c5do7A_ 7 c5xjyA_ 8 c5gasN_ 9 c5ir6B_ 10 c3cqyA_ 11 c4yh5B_ 12 c5n9yB_ 13 c3rkoF_ 14 c2k9yA_ 15 c2k9yB_ 16 c2x7lP_ 17 c3lphD_ 18 c5ir6A_