vapB6
rv0657c
antitoxin VapB6
M. tuberculosis · H37Rv
[MycoBrowser] [AlphaFold] [UniProt] [Orthologs] [U19] [TnSeq DB] [SeqHub]
H37Rv Coordinates: 753465 – 753620
Vulnerability Index (VI):
M. smegmatis homologs
M. abscessus homologs
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 Rv0654 mkl Rv0656c Rv0657c Rv0658c Rv0659c Rv0660c Rv0661c Rv0662c atsD
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>rv0657c_vapB6_dna
CGCTGGGGTCGGTGGGCGGCGCTGGTGGTTACCACCGTGGTCTTCGCATTGGCCCATCTCGAGTTCGCCCGAGCTCCACTGCTGGTGGTGGTGGCCATCCCGATCGCGCTGGCACGGTTCTATTCCGGCGGTCTACTGGCCAGCATCGTCACGCACCAAGTGACCAACCTATTGCCCGGGATCGTATTGCTGCTTGGTCTGACTGGCGCCATATCGTTGCCCTGAGCAGGCGCGAGACGGTCTCCTCGCGATGTTGGTTACGTATGTTTATGTGATATGTCTTCAACATAGGAGGCCGTCGTGTCGGTGACCCAGATCGACCTCGACGACGAAGCGCTGGCCGATGTGATGCGCATCGCCGCCGTGCACACAAAGAAGGAAGCCGTGAACCTCGCGATGCGCGATTACGTCGAACGGTTTCGGCGCATCGAGGCCCTGGCCCGCTCGCGCGAGTAG

Protein Sequence 

>Rv0657c_VapB6_protein
VSVTQIDLDDEALADVMRIAAVHTKKEAVNLAMRDYVERFRRIEALARSRE

Essentiality:

Call Condition Type Source Notes
Growth Advantage in vitro TnSeq [DeJesus et al. (2017)]
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]

You do not have permission to view notes.