vapB8
rv0664
antitoxin VapB8
M. tuberculosis · H37Rv
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H37Rv Coordinates: 758535 – 758807
Vulnerability Index (VI):
M. smegmatis homologs
M. abscessus homologs
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 Rv0661c Rv0662c atsD Rv0664 Rv0665 Rv0666 rpoB
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>rv0664_vapB8_dna
GGGCGGCGAGGTAACTCTTTATGTCGACGGCCAACAGGTCGGCGAAGGACATGTCGAAGCCACCCTTGCCATCGTCTTCTCGGCCGACGACGGCTGCGATGTCGGCATGGATTCGGGCTCGCCCGTCTCACCCGACTATGCCCCGGGGAGTAACGCGTTCAACGGGCGGATCAAGGGCGTGCAGCTCGCGATCGCCGAGGCCGCCGCTGCTGCGGGCCATCTGGTCGACCCGGAGCACGCGATCCGCATCGCGCTGGCGCGCCAATAGGGCCGCACAGTCAAACGGGGAGGGGACGGCGATGGAAAAGTCACGGTGCCACGCTGTCGCACATGGAGGTGGGTGTGCGGGATCTGCGAAATCGCACAAGTCAGGTGGTCGATGCGGTCAAGGCCGGGGTGCCGGTGACTCTCACGGTACACGGGGAGCCGGTCGCCGATATCGTGCCGCATCGGCGCCGCATCCGCTGGCTGTCGGGGCGCATCTGCGCGATGAGCTCGCCAAGCGCTCGGCCGACCCGCGCCTCACCGATGAACTCAACGACTTGGCCGGTCATACCCTCGACGACCTGTGA

Protein Sequence 

>Rv0664_VapB8_protein
MEKSRCHAVAHGGGCAGSAKSHKSGGRCGQGRGAGDSHGTRGAGRRYRAASAPHPLAVGAHLRDELAKRSADPRLTDELNDLAGHTLDDL

Essentiality:

Call Condition Type Source Notes
Non Essential in vitro TnSeq [DeJesus et al. (2017)]
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]

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