PE_PGRS17
rv0978c
PE-PGRS family protein PE_PGRS17
M. tuberculosis · H37Rv
[MycoBrowser] [AlphaFold] [UniProt] [Orthologs] [U19] [TnSeq DB] [SeqHub]
H37Rv Coordinates: 1093365 – 1094360
Vulnerability Index (VI):
M. smegmatis homologs
M. abscessus homologs
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 PE_PGRS16 PE_PGRS17 rpmF Rv0979c PE_PGRS18 mprA
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>rv0978c_PE_PGRS17_dna
AGCGGTCGCCTCACCGGTCGTCGACATGGGGCCGGTTCAGTGCGCTGACCGGTGAGCGTGAGCAGCGATTTGTGCTGCTTAACGCAGGAGTTCTCGTCCGCGCGGGTTTCGCCTGCTGACACACGATGAGGGCAGAACCCCAGGTGCAGTGTGCACCACGTTCCACCAATGTTGGTGCGGTTTGCGCCTGCGCCCAGGCGTGGAACGGCAGGGATCGTCCGAATAAACGGTTACCCACCGCGGCGGTAACAGGCGGTGGGCCGCCCGCATCTCAACATCGTGGCGGTCAGGAGGATTTCGATGTCGTTTGTCAACGTGGCCCCACAGTTAGTGTCCACAGCCGCGGCCGATGCAGCGCGGATCGGCTCGGCGATCAACACCGCCAACACCGCGGCGGCGGCGACCACCCAGGTGTTGGCCGCCGCCCAAGACGAGGTGTCAACGGCGATCGCCGCGCTGTTCGGCAGCCACGGCCAGCACTATCAAGCGATCAGCGCGCAGGTCGCGGCCTATCAGCAACGGTTCGTGCTGGCCTTAAGCCAAGCTGGCAGCACCTACGCGGTCGCCGAAGCGGCCAGCGCAACACCGCTGCAGAACGTGCTCGATGCGATCAACGCACCCGTTCAGTCGCTGACCGGGCGCCCATTGATCGGCGACGGCGCGAACGGGATCGACGGGACCGGGCAAGCCGGCGGTAACGGCGGGTGGCTGTGGGGCAACGGCGGCAACGGCGGGTCGGGGGCACCCGGACAGGCCGGCGGCGCCGGCGGGGCGGCCGGGTTGATCGGCAACGGTGGGGCCGGCGGCACCGGCGGCGCGGTCAGCCTCGCCCGCGCCGGCACGGCCGGCGGTGCCGGCCGCGGCCCGGTCGGCGGTATCGGCGGTGCGGGTGGGGTCGGCGGTGCCGGTGGGGCCGCCGGCGCCGTCACCACCATCACCCACGCCAGCTTCAACGATCCGCACGGGGTGGCGGTCAACCCGGGCGGCAACGTCTACGTCACCAATTTCGGCAGCGGCACGGTGTCGGTGATCAACCCCGCCACCAACACCGTCACCGGCTCCCCCATCACCATCGGCAACGGTCCAAGCGGGGTGGCGGTCAGCCCCGTCACCGGCCTGGTCTTCGTGACCAACTTCGACAGCAACACGGTGTCGGTGATCGACCCGACCACCAACACCGTCACCGGCTCCCCCATCACCGTCGGCACCGCTCCGACCGGGGTGGCGGTCAACCCCGTCACCGGCGAGGTCTATGTCACCAACTTCGCCGGCGACACGGTGTCGGTAATCAGCTGA

Protein Sequence 

>Rv0978c_PE_PGRS17_protein
MSFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAQDEVSTAIAALFGSHGQHYQAISAQVAAYQQRFVLALSQAGSTYAVAEAASATPLQNVLDAINAPVQSLTGRPLIGDGANGIDGTGQAGGNGGWLWGNGGNGGSGAPGQAGGAGGAAGLIGNGGAGGTGGAVSLARAGTAGGAGRGPVGGIGGAGGVGGAGGAAGAVTTITHASFNDPHGVAVNPGGNVYVTNFGSGTVSVINPATNTVTGSPITIGNGPSGVAVSPVTGLVFVTNFDSNTVSVIDPTTNTVTGSPITVGTAPTGVAVNPVTGEVYVTNFAGDTVSVIS

Essentiality:

Call Condition Type Source Notes
Growth Advantage in vitro TnSeq [DeJesus et al. (2017)]
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]

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