Rv0978c (PE_PGRS17)

background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 PE_PGRS16 PE_PGRS17 rpmF Rv0979c PE_PGRS18 mprA
Species: M. tuberculosis
Strain: H37Rv
PATRIC Annotation: PE-PGRS family protein PE_PGRS17
Synonyms:
M. smegmatis homologs
M. abscessus homologs
Gene Start: 1093365
Gene End: 1094360
Vulnerability Index (VI):
VI Lower Bound:
VI Upper Bound:
[AlphaFold] [UniProt] [MycoBrowser] [Phyre2] [Orthologs] [U19] [TnSeq DB]

Essentiality:

Call Condition Type Source Notes
Growth Advantage in vitro TnSeq [DeJesus et al. (2017)]
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]


DNA and Protein Sequence help

DNA Sequence

AGCGGTCGCCTCACCGGTCGTCGACATGGGGCCGGTTCAGTGCGCTGACCGGTGAGCGTGAGCAGCGATTTGTGCTGCTTAACGCAGGAGTTCTCGTCCGCGCGGGTTTCGCCTGCTGACACACGATGAGGGCAGAACCCCAGGTGCAGTGTGCACCACGTTCCACCAATGTTGGTGCGGTTTGCGCCTGCGCCCAGGCGTGGAACGGCAGGGATCGTCCGAATAAACGGTTACCCACCGCGGCGGTAACAGGCGGTGGGCCGCCCGCATCTCAACATCGTGGCGGTCAGGAGGATTTCGATGTCGTTTGTCAACGTGGCCCCACAGTTAGTGTCCACAGCCGCGGCCGATGCAGCGCGGATCGGCTCGGCGATCAACACCGCCAACACCGCGGCGGCGGCGACCACCCAGGTGTTGGCCGCCGCCCAAGACGAGGTGTCAACGGCGATCGCCGCGCTGTTCGGCAGCCACGGCCAGCACTATCAAGCGATCAGCGCGCAGGTCGCGGCCTATCAGCAACGGTTCGTGCTGGCCTTAAGCCAAGCTGGCAGCACCTACGCGGTCGCCGAAGCGGCCAGCGCAACACCGCTGCAGAACGTGCTCGATGCGATCAACGCACCCGTTCAGTCGCTGACCGGGCGCCCATTGATCGGCGACGGCGCGAACGGGATCGACGGGACCGGGCAAGCCGGCGGTAACGGCGGGTGGCTGTGGGGCAACGGCGGCAACGGCGGGTCGGGGGCACCCGGACAGGCCGGCGGCGCCGGCGGGGCGGCCGGGTTGATCGGCAACGGTGGGGCCGGCGGCACCGGCGGCGCGGTCAGCCTCGCCCGCGCCGGCACGGCCGGCGGTGCCGGCCGCGGCCCGGTCGGCGGTATCGGCGGTGCGGGTGGGGTCGGCGGTGCCGGTGGGGCCGCCGGCGCCGTCACCACCATCACCCACGCCAGCTTCAACGATCCGCACGGGGTGGCGGTCAACCCGGGCGGCAACGTCTACGTCACCAATTTCGGCAGCGGCACGGTGTCGGTGATCAACCCCGCCACCAACACCGTCACCGGCTCCCCCATCACCATCGGCAACGGTCCAAGCGGGGTGGCGGTCAGCCCCGTCACCGGCCTGGTCTTCGTGACCAACTTCGACAGCAACACGGTGTCGGTGATCGACCCGACCACCAACACCGTCACCGGCTCCCCCATCACCGTCGGCACCGCTCCGACCGGGGTGGCGGTCAACCCCGTCACCGGCGAGGTCTATGTCACCAACTTCGCCGGCGACACGGTGTCGGTAATCAGCTGA

Protein Sequence

MSFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAQDEVSTAIAALFGSHGQHYQAISAQVAAYQQRFVLALSQAGSTYAVAEAASATPLQNVLDAINAPVQSLTGRPLIGDGANGIDGTGQAGGNGGWLWGNGGNGGSGAPGQAGGAGGAAGLIGNGGAGGTGGAVSLARAGTAGGAGRGPVGGIGGAGGVGGAGGAAGAVTTITHASFNDPHGVAVNPGGNVYVTNFGSGTVSVINPATNTVTGSPITIGNGPSGVAVSPVTGLVFVTNFDSNTVSVIDPTTNTVTGSPITVGTAPTGVAVNPVTGEVYVTNFAGDTVSVIS_ 
Gene not present in the RLC0012 CRISPRi library.

Specific References

General References