rv2060
rv2060
zinc/manganese transporter permease
M. tuberculosis · H37Rv
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H37Rv Coordinates: 2316287 – 2316688
Vulnerability Index (VI):
M. smegmatis homologs MSMEG6045
M. abscessus homologs MAB0575c
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 Rv2054 rpsR rpsN rpmG rpmB Rv2059 Rv2060 Rv2061c cobN
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>rv2060_Rv2060_dna
GGCAGCCGGCCTGAAAAATCGAACCCCGGCTACCTTCATCGCGGCCAACGAAAACGGCAACGACCCCACCCCGGCCGATATGGCGGCCGTGCTCGACATGATCGCCGGCCGTGAGGTCGCGGCGTTGCTGGTTAACCCGCAGACACCTACCGCGGCGACCGACGAACTGCAGGTGGCCGCCCGGCGGGCAGGAGTGCCAATCACCGAGTTGACCGAGACCTTGCCCAGCGGAACCGACCGGGACCAGTTTTGCGCTGCTGACCGGCCAGATCGTCGGGGTCGGTCACTCCGGGCTGACCATGCTGACCGTGGTTTGTCTGCTCGTGGTCACCGTGTTGGCGATCTGCTACCGACCGCTCTTGTTTGCCACCGTCGATCCGGAGGTCGCGGCCGCCCGCGGCGTGCCAGTGCGCGCCCTGGGAATTGTGTTCGCCGCACTGATGGGCGTGGTAGCCGCCCAGGCTGTCCAGATCGTCGGGGCACTCCTCGTGATGTCTTTGCTGATCACCCCCGCCGCGGCGGCCGCCCGGGTCGTGGTTGCCCCGGTCGCCGCGATCGCGACCTCGGTGGTCTTCGCCGAGGTTTCCGCCGTCGGCGGCATCCTGCTGTCGCTGGCGCCTGGAGTCCCGGTGTCGGTGTTCGTGGCCACCATCTCGTTTGTGATCTACCTGATTTGCTGGTTGCTCCGGCGGCGCCGCTAA

Protein Sequence 

>Rv2060_Rv2060_protein
MLTVVCLLVVTVLAICYRPLLFATVDPEVAAARGVPVRALGIVFAALMGVVAAQAVQIVGALLVMSLLITPAAAAARVVVAPVAAIATSVVFAEVSAVGGILLSLAPGVPVSVFVATISFVIYLICWLLRRRR

Essentiality:

Call Condition Type Source Notes
Non Essential in vitro TnSeq [DeJesus et al. (2017)]
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]

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