rv2168c
rv2168c
transposase
M. tuberculosis · H37Rv
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [U19] [TnSeq DB] [SeqHub] [evo-mtb]
H37Rv Coordinates: 2431102 – 2431428
Vulnerability Index (VI):
M. smegmatis homologs MSMEG2676, MSMEG0724, MSMEG1720, MSMEG1716, MSMEG5096, [+ 5 remaining orthologs]
M. abscessus homologs MAB2087
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon TSS Legend ? Ju, 2024 (4) Cortes, 2013 (5) Shell, 2015 (3) (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 38418874 (5) PMID: 24268774 Rv2164c mraW Rv2166c Rv2167c Rv2168c Rv2169c Rv2170 lppM Rv2172c
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>rv2168c_Rv2168c_dna
GGTGTGGTGTATGCCATCACCGGTCCTCGGTTGTCCGGCAGGATGGATCGTGGCGGATCGGCTGCTGGGGCTTCGCGCCAGCGTCGTACCAAGGGGGCCGGGGGCTCATTCACCAGCCGTATGGAAGATCGGTTCCGGCGCCGCTTCGACGAGTAAGCCGAACGCAACCAGCGGCAGCGGGGCAGCCATCGGCGGTCCCGCTTTTTGTTTGGGCGTCATCGTTTGGGAATCGCAGTCTCGGGAAGCCCCTGAACCGCCCCGGCATGTCCGGAGACTCCAGTTCTTGGAAAGGATGGGGTCATGTCAGGTGGTTCATCGAGGAGGTACCCGCCGGAGCTGCGTGAGCGGGCGGTGCGGATGGTCGCAGAGATCCGCGGTCAGCACGATTCGGAGTGGGCAGCGATCAGTGAGGTCGCCCGTCTACTTGGTGTTGGCTGCGCGGAGACGGTGCGTAAGTGGGTGCGCCAGGCGCAGGTCGATGCCGGCGCACGGCCCGGGACCACGACCGAAGAATCCGCTGAGCTGAAGCGCTTGCGGCGGGACAACGCCGAATTGCGAAGGGCGAACGCGATTTTAAAGACCGCGTCGGCTTTCTTCGCGGCCGAGCTCGACCGGCCAGCACGCTAA

Protein Sequence 

>Rv2168c_Rv2168c_protein
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASAFFAAELDRPAR

Essentiality:

Call Condition Type Source Notes
Non Essential in vitro TnSeq [DeJesus et al. (2017)]
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]

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