rv3186
rv3186
transposase
M. tuberculosis · H37Rv
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [U19] [TnSeq DB] [SeqHub] [evo-mtb]
H37Rv Coordinates: 3552761 – 3553087
Vulnerability Index (VI):
M. smegmatis homologs MSMEG2676, MSMEG0724, MSMEG1720, MSMEG1716, MSMEG5096, [+ 5 remaining orthologs]
M. abscessus homologs MAB2087
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 38418874 Rv3181c Rv3182 Rv3183 Rv3184 Rv3185 Rv3186 Rv3187 Rv3188 Rv3189 Rv3190c
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>rv3186_Rv3186_dna
CAGTACTGCGGCGACGTCCCGCCGGTCGAACTCGAGGCTGCCTACTACGCTCAACGCCAGAGACCAGCCGCCGGCTGAGGTCTCAGATCAGAGAGTCTCCGGACTCACCGGGGCGGTTCACGAACCTGCGACCTCTGGGTTATGAGCTAACCAGTCGCAATCTCTCCCATCGCGGTCGGTCTCATACGTCCAGATCAGCCTCTATTCCGCCGTCCAGCCTGTTCCGCCGCGTCGCGGTTGTACGGATTTGAACCGCCCCGGCATGTCCGGAGACTCCAGTTCTTGGAAAGGATGGGGTCATGTCAGGTGGTTCATCGAGGAGGTACCCGCCGGAGCTGCGTGAGCGGGCGGTGCGGATGGTCGCAGAGATCCGCGGTCAGCACGATTCGGAGTGGGCAGCGATCAGTGAGGTCGCCCGTCTACTTGGTGTTGGCTGCGCGGAGACGGTGCGTAAGTGGGTGCGCCAGGCGCAGGTCGATGCCGGCGCACGGCCCGGGACCACGACCGAAGAATCCGCTGAGCTGAAGCGCTTGCGGCGGGACAACGCCGAATTGCGAAGGGCGAACGCGATTTTAAAGACCGCGTCGGCTTTCTTCGCGGCCGAGCTCGACCGGCCAGCACGCTAA

Protein Sequence 

>Rv3186_Rv3186_protein
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASAFFAAELDRPAR

Essentiality:

Call Condition Type Source Notes
Non Essential in vitro TnSeq [DeJesus et al. (2017)]
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]

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