rv3224B
rv3224B
hypothetical protein
M. tuberculosis · H37Rv
[AlphaFold] [UniProt] [MycoBrowser] [Orthologs] [U19] [TnSeq DB] [SeqHub] [evo-mtb]
H37Rv Coordinates: 3600798 – 3601016
Vulnerability Index (VI):
M. smegmatis homologs ybaK
M. abscessus homologs MAB3544
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon TSS Legend ? Ju, 2024 (5) Cortes, 2013 (4) Shell, 2015 (3) (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 24268774 (5) PMID: 38418874 Rv3221A Rv3222c sigH Rv3224 Rv3224A Rv3224B Rv3225c Rv3226c aroA
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>rv3224B_Rv3224B_dna
GAGGTATACGCCGACGCGGCCTACGTCATCGTCAACAAGCCCGCCACCGAATACACCGGCAAGACGCTGCTGTGCGAGGACGTGCTCGTCGAATCCGGCGTCACCGACTTGTCGGTCTACGACTGCGTCCCAGGTGCGACGCTCGGCGTCGACCTGTGGGTGGAAGACGCCAACCCGCCGGGGTACCTCCCGGCCTAGCGACAGCAAAACCCTGATCCTCGAGTTGCCCGACGAGCGGGCCGTCGCGATCGTGCCGGTGCCGTCGAAGTTGTCGCTGAAGGCGGCCGGCGGCCCTAGGGGTGCCCAAAGCGGCCATGGCTAAACCCGCTGCCGCCGAACAAGCCACCGGCTACGTGGTCGGCGGCATCTCCCCGTTCGGTCAGCGCAAGCGGCTGCGGACCGTGGTCGATGTGTCGGCCTTGAGCTGGGACCGGGTACTGCGGTGCCGGCAAACGGCATTGGGCCGTCACGGTGGCCCCGCCGGACCTGATCACCTTGATCAGCGCGATCATCGCTAA

Protein Sequence 

>Rv3224B_Rv3224B_protein
VPKAAMAKPAAAEQATGYVVGGISPFGQRKRLRTVVDVSALSWDRVLRCRQTALGRHGGPAGPDHLDQRDHR

Essentiality:

Call Condition Type Source Notes
Non Essential in vitro TnSeq [DeJesus et al. (2017)]
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]

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