rv3453
rv3453
transmembrane protein
M. tuberculosis · H37Rv
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H37Rv Coordinates: 3874583 – 3874915
Vulnerability Index (VI):
M. smegmatis homologs
M. abscessus homologs MAB2635c
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon TSS Legend ? Ju, 2024 (4) Cortes, 2013 (5) Shell, 2015 (3) (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 38418874 (5) PMID: 24268774 Rv3450c cut3 cut4 Rv3453 Rv3454 truA rplQ rpoA
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>rv3453_Rv3453_dna
GGCGCGTTTCGTCGCGAGCAGGATCTAACGCGAGCCGCCCCATAGATTCCGGCTAAGCAACGGCTGCGCCGCCGCCCGGCCACGAGTGACCGCCGCCGACTGGCACACCGCTTACCACGGCCTTATGCTGGCGCCGGACCCCGCCCGCCAGGCGCGCCGCCCGTCAACGCAGCCGAATGCGCATTTGTCCGCCGAATGCGCCGCGATGAACCGCAATCATTTCACCGGAAGGGAAGTGTGCGGACACGCTAACCGGACGCTCGGGCTAACTTCGACCGCTATTGCGCTGAGGAGGGTTGATGCCGGGCGTCATAACAAACAGTGAAAGCCCAACCGCAGCCGACCACGACAGAATTACGGCCACCAGAGAGACGCTGGAGGATTACACACTGCGGTTGGCGCCGCGCAGCTATCGCAGGTGGCCCCCGGCGGTGGTGGGCATCTCCGCTCTCGGCGGCATCGCCTACCTGGCGGACTTCGCGATCGGCGCCAATGTCGGTATCACGTGGGGTACCGCGAACGCGCTGTGCGGAATCGCAATCTTCGCACTGGTGGTCTTCGTCACCGGCTTGCCGCTGGCCTACTACGCGGCGCGGTACAACATCGACCTGGATCTGATTTACCCGCGGTAG

Protein Sequence 

>Rv3453_Rv3453_protein
MPGVITNSESPTAADHDRITATRETLEDYTLRLAPRSYRRWPPAVVGISALGGIAYLADFAIGANVGITWGTANALCGIAIFALVVFVTGLPLAYYAARYNIDLDLIYPR

Essentiality:

Call Condition Type Source Notes
Non Essential in vitro TnSeq [DeJesus et al. (2017)]
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]

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