rv3474
rv3474
transposase
M. tuberculosis · H37Rv
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [U19] [TnSeq DB] [SeqHub] [evo-mtb]
H37Rv Coordinates: 3891009 – 3891335
Vulnerability Index (VI):
M. smegmatis homologs MSMEG2676, MSMEG0724, MSMEG1720, MSMEG1716, MSMEG5096, [+ 5 remaining orthologs]
M. abscessus homologs MAB2087
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 38418874 ilvB2 Rv3471c Rv3472 bpoA Rv3474 Rv3475 kgtP PE31
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>rv3474_Rv3474_dna
GCCGGCTGCCCAGGCAGGTTGCGCAGCACTTCCTGGATATCGCCGGCGAAGCTGACCAACCGATAGTCGCCTTCGCTCGACCAGTCGGATTCGCCATGCCCGCGCAGATCGATCGTGACCGCTTGCCAGCCACGTTCGGCGACAGCGGCTGCGGCCCGACCCCATGAGCGTCGCGTCTGTCCACCGCCATGCAAGAACACCACGGCACGCGCTCGCGGGTCTCCCAAGCGGTCGGCGACGATACGGACTGAACCGCCCCGGCATGTCCGGAGACTCCAGTTCTTGGAAAGGATGGGGTCATGTCAGGTGGTTCATCGAGGAGGTACCCGCCGGAGCTGCGTGAGCGGGCGGTGCGGATGGTCGCAGAGATCCGCGGTCAGCACGATTCGGAGTGGGCAGCGATCAGTGAGGTCGCCCGTCTACTTGGTGTTGGCTGCGCGGAGACGGTGCGTAAGTGGGTGCGCCAGGCGCAGGTCGATGCCGGCGCACGGCCCGGGACCACGACCGAAGAATCCGCTGAGCTGAAGCGCTTGCGGCGGGACAACGCCGAATTGCGAAGGGCGAACGCGATTTTAAAGACCGCGTCGGCTTTCTTCGCGGCCGAGCTCGACCGGCCAGCACGCTAA

Protein Sequence 

>Rv3474_Rv3474_protein
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASAFFAAELDRPAR

Essentiality:

Call Condition Type Source Notes
Non Essential in vitro TnSeq [DeJesus et al. (2017)]
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]

You do not have permission to view notes.