esxV
rv3619c
ESAT-6 like protein EsxV
M. tuberculosis · H37Rv
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H37Rv Coordinates: 4060163 – 4060447
Vulnerability Index (VI):
M. smegmatis homologs
M. abscessus homologs
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 ephA Rv3618 esxV esxW PPE65 PE32 lpqG hpt
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>rv3619c_esxV_dna
TCCGCACGCGATGCGGGACATGGCGGGCCGTTTTGAGGTGCACGCCCAGACGGTGGAGGACGAGGCTCGCCGGATGTGGGCGTCCGCGCAAAACATTTCCGGCGCGGGCTGGAGTGGCATGGCCGAGGCGACCTCGCTAGACACCATGACCCAGATGAATCAGGCGTTTCGCAACATCGTGAACATGCTGCACGGGGTGCGTGACGGGCTGGTTCGCGACGCCAACAACTACGAACAGCAAGAGCAGGCCTCCCAGCAGATCCTCAGCAGCTGACCCGGCCCGACGACTCAGGAGGACACATGACCATCAACTATCAATTCGGGGACGTCGACGCTCACGGCGCCATGATCCGCGCTCAGGCCGGGTCGCTGGAGGCCGAGCATCAGGCCATCATTTCTGATGTGTTGACCGCGAGTGACTTTTGGGGCGGCGCCGGTTCGGCGGCCTGCCAGGGGTTCATTACCCAGCTGGGCCGTAACTTCCAGGTGATCTACGAGCAGGCCAACGCCCACGGGCAGAAGGTGCAGGCTGCCGGCAACAACATGGCACAAACCGACAGCGCCGTCGGCTCCAGCTGGGCCTAA

Protein Sequence 

>Rv3619c_EsxV_protein
MTINYQFGDVDAHGAMIRAQAGSLEAEHQAIISDVLTASDFWGGAGSAACQGFITQLGRNFQVIYEQANAHGQKVQAAGNNMAQTDSAVGSSWA

Essentiality:

Call Condition Type Source Notes
Non Essential in vitro TnSeq [DeJesus et al. (2017)]
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]

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