MSMEG0074
ms0074
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 96469 – 97935
Vulnerability Index (VI):
M. tuberculosis homologs
M. abscessus homologs
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon TSS Legend ? Ju, 2024 (4) Li, 2017 (5) (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 38418874 (5) PMID: 29326668 MSMEG0071 MSMEG0072 MSMEG0073 MSMEG0074 MSMEG0075 MSMEG0076
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms0074_MSMEG0074_dna
TGGTTGGCCTCGGAGATCATGCCCGCATCGGCGACCACGGTGACATCGGTGAGTTGATGGGCGGCCTTGAACGCGTTGATCACCGGCAGCATGGTGGCGGTCTCGGCGCGGTTGCCCTCGAAGGCCTCCACGGTCAGCGGGACCTGACTTGGCTCACGGTTTCCGGTTTGGGGTAGTGGCGGGTTCTTGACCTGCAGTTTCGGAGTCGGCTCGGCCGGAATTTGCGCACTAAGGTCGGGCCGTAGGCTGCCCTGGTGGCGTACGTGCGCACAGTGAAGACCGCTTCGGGGGCCACTGCGGTGCAGATCGTGTGGTCCACCCGACGCGGGTCACGCAACATCGAGCATGTGGGCTCGGCCCATGATGAGGCCGAGCTCGCAGCGCTCAAGGCCTCCGCTGCCGAGCGGTTGGCGGCCAACCAGGCGGTGCTGGATCTGGAGGTGTCCCCGCCGGCCGGTTCGGAGCCGTTGCCGATCACCTCCTCACAGATGACCCATCTGTGGGACGGGCTCTGTTCGGCGTATCGGATCCTCGGGTTCGACTCAGCCGCCGAGGGCGACAATGTGTTTCGGGATCTGGTGCTGGCCAGGATCATCGAACCCAGCAGCAAGGCCGACGCCGGACGGGTGCTCACCGAGGTCGGTGTCGAACCGGCCTCCTATGCCACGGTCAAACGCCGGCTGCCGATCTACGCCCAGCCGCAGTGGCGGCAGTCCTTGGCCGCGGCCAGTGCACGTCGCGCCGGGTTGGGGCCCGCATCGCTGGTGCTATTCGATGTGAGCACCTTGTATTTCGAGACCGACGCCGGCGACGGCTTCCGCGAGCCCGGATTCTCCAAGGAACGCCGACTCGAGCCGCAGATCACCCTGGGGTTGCTTACCGATGCCGCCGGGTTCCCGCTGACCGTGGAGGCCTTCGAGGGCAACCGCGCCGAGACCGCCACCATGCTGCCGGTGATCAACGCGTTCAAGGCCGCCCATCAACTCACCGATGTCACCGTGGTCGCCGATGCGGGCATGATCTCCGAGGCCAACCAGGTCGCGCTGCAGTCCGCCGGCCTGTCCTACATCCTCGGCGCCAAGATTCCGTTCCTGCCCGATGTGGTGCGCGAATGGCGGGACAAACACCCCGACGAGGCGATCCCCGATGGCCTGGTGCTCACCCAACCGTGGCCGGCCACCAGCAGCGAGAAGGCCCGCGGCATCCCGGACCGGGTCATCCACTACCAATTCCGCCACGACCGCGCCCGGCGCACCCTGCGCGGCATCGACGAGCAAGTGGCCAAGGCCCAGCGCGCAGTCGACGGGCACGCCCCGGTCAAGCGCAACCGCTACATCCAACTCACTGGCGCCACCAAGTCGGTGAACCGCACGCTGGAGGCCAAGACCCGCGCCCTGGCCGGCTGGAAGGGCTACACCACCAACCTCGTCGGGCAGCCCGCGTCGTTTGTCATCGATGCCTATCACCAGCTCTGGCACATCGAGAAGGCCTTCCGGATGTCCAAGCACGACCTGCAGGCCCGCCCGATCTACCACCATTTACGCGAATCGATCGAAGCCCACCTGAGCATCGTGGTCGCCGCAATGGCCGTCAGCCACTTCATCGAGACCCAAACCGGCTGGAGCATCAAGAAATTCGTCCGAACCGCACGCCGCTACCGCACCGTGAAGATCAAGGCCGGCACCCAGACCCTCACCGCCGCCGACCCGCTACCCGAGGACCTACGAGCAGTCCTCATCAAGATCCGCGCCGACGGTGCACACTAA

Protein Sequence 

>Ms0074_MSMEG0074_protein
VQIVWSTRRGSRNIEHVGSAHDEAELAALKASAAERLAANQAVLDLEVSPPAGSEPLPITSSQMTHLWDGLCSAYRILGFDSAAEGDNVFRDLVLARIIEPSSKADAGRVLTEVGVEPASYATVKRRLPIYAQPQWRQSLAAASARRAGLGPASLVLFDVSTLYFETDAGDGFREPGFSKERRLEPQITLGLLTDAAGFPLTVEAFEGNRAETATMLPVINAFKAAHQLTDVTVVADAGMISEANQVALQSAGLSYILGAKIPFLPDVVREWRDKHPDEAIPDGLVLTQPWPATSSEKARGIPDRVIHYQFRHDRARRTLRGIDEQVAKAQRAVDGHAPVKRNRYIQLTGATKSVNRTLEAKTRALAGWKGYTTNLVGQPASFVIDAYHQLWHIEKAFRMSKHDLQARPIYHHLRESIEAHLSIVVAAMAVSHFIETQTGWSIKKFVRTARRYRTVKIKAGTQTLTAADPLPEDLRAVLIKIRADGAH

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Growth Advantage in vitro TnSeq [Dragset et al. (2019)]

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