MSMEG1591
ms1591
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1678351 – 1679754
Vulnerability Index (VI):
M. tuberculosis homologs
M. abscessus homologs
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG1586 MSMEG1587 MSMEG1588 MSMEG1589 MSMEG1590 MSMEG1591 MSMEG1592 MSMEG1593 MSMEG1594 MSMEG1595
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1591_MSMEG1591_dna
TGCTGCTGGGACCCGTGCTGGAAGTGGTGTCCGATGCCGAGACGCTGTCGGTTTCGGCCGCGGCGATTCCAGGGCTGGTGCAGACAAGCACCAGGCCGGCGGAGAGGAGACACGCACCCGCCGTCAGTTGAATACCGGTAACAATCGGGAGACTCCTCGCAGTAACGCCGCGATACTTAGCCTCGATCCACCGATGAATCGCCTGGTCGGAGGGTGTTGATATAAGGAAAGTGCCCTTTGAGCTGGGATGATTGGAGTTACCACACTTCGATCAGCCCACGGTCAGAAAGGCACTTCCGGTGCAAGTGTCCCATAGGTTCGCCGTGTCGTCGGCGGTCTTCGATGATGCCCATCTCGTGTCGTGCGCCGGGCTGGTGCCGGTGATGACGTTGGCGGCCCAGACCGGACTACCGAAGTTGTTGGCCGACAAGATTTCCATTCCGGCACCGAAGATCAAATCCGGCTCGGCGAATCCGTCCCCGAAGCTGACCACGGTGATCGCCGGCATGTGTGTCGGCGCGGACAGCATTGATGACCTCGACCTCGTGCGTGGCGGCGGGATGAAGACACTCTTTGGCGGTGTGTATGCACCGTCAACTGTTGGTACTTTGTTGCGGGAGTTCACCTTCGGACACGCCCGGCAGTTGGAGTCGGTCCTGCGTCATCATCTGGCCGCACTCTGTGCGCGGGTGGACCTGCTGCCCGGATCCGACACGGGGGCGTTCATCGACATCGACTCACTGCTGCGCCCGGTCTATGGCCACGCCAAACAGGGTGCCTCCTACGGGCATACCAAGATCGCTGGTAAGCAGGTTCTGCGTAAAGGGCTCTCCCCGTTGGCGACGACGATCAGCACCCCCGGAGCGGCGCCGGTGATCGCCGGGATGCGGCTGCGCGCCGGTAAGACCAGTTCCGGGAAGGGTGCGGGCCGCATGGTCGCCCAAGCCATCGCCACCGCCCGCGCCGCCGGCGTGCGCGGGCAACTGCTGGTGCGTGGCGATTCGTCCTACGGCACCCGGTCGGTGGTGGGCGCCTGCCGAGCCCACAATGCGCACTTCTCGGTGGTGATGACCCGCAATACCGCGGTTGATCGGGCCATCAGTTCGATCGACGAGCAGGCCTGGGAGCCGGTCAACTATCCCGGTGCAGTGCGTGATCCCGACACCGGTGACTGGATTTCTGATGCCGAGGTCGCCGAGGTCAGCTACACCGCCTTCGCCTCTACCAAAGATCGGTTCACCGCGCGGTTGGTGGTGCGGCGAGTCAAAGACGCGAGATTTCGGGACGCGCTGTTCCCGGTGTGGCGGTATCACCCGTTCTTCACCAACACAGACTTGCCGACCGCCGAGGCTGACATCACCCACCGCCAGCACGCGATCATCGAAACCGTCTTCGCCGATCTGATCGACGGACCCCTGGCCCACATGCCCTCAGGACAGTTCGGTGCCAACAGTGCGTGGGTGTTGTGCGCGGCGATCGCGCACAACCTGCTGCGCGCCGCCGGCGTGCTCGCAGGAGGTGCCCACGTGGTTGCCCGCGGCGCGACGCTGCGCCGCAAGATCGTCAACATTCCCGCCCGTCTGGCCCGACCCCAGCGTCGACCGATCCTGCACCTCCCCGAGCACTGGCCCTGGACAGAGCACTGGCTCACGTTGTGGCGCAACACCATCGGATACAGCCCACCGCTACCGGCAACGACCTGA

Protein Sequence 

>Ms1591_MSMEG1591_protein
VQVSHRFAVSSAVFDDAHLVSCAGLVPVMTLAAQTGLPKLLADKISIPAPKIKSGSANPSPKLTTVIAGMCVGADSIDDLDLVRGGGMKTLFGGVYAPSTVGTLLREFTFGHARQLESVLRHHLAALCARVDLLPGSDTGAFIDIDSLLRPVYGHAKQGASYGHTKIAGKQVLRKGLSPLATTISTPGAAPVIAGMRLRAGKTSSGKGAGRMVAQAIATARAAGVRGQLLVRGDSSYGTRSVVGACRAHNAHFSVVMTRNTAVDRAISSIDEQAWEPVNYPGAVRDPDTGDWISDAEVAEVSYTAFASTKDRFTARLVVRRVKDARFRDALFPVWRYHPFFTNTDLPTAEADITHRQHAIIETVFADLIDGPLAHMPSGQFGANSAWVLCAAIAHNLLRAAGVLAGGAHVVARGATLRRKIVNIPARLARPQRRPILHLPEHWPWTEHWLTLWRNTIGYSPPLPATT

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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