MSMEG2676
ms2676
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 2753996 – 2754322
Vulnerability Index (VI):
M. tuberculosis homologs Rv3474, Rv3381c, Rv3325, Rv3186, Rv3184, [+ 12 remaining orthologs]
M. abscessus homologs
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG2672 MSMEG2675 MSMEG2676 MSMEG2677 MSMEG2678 MSMEG2679 MSMEG2680
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms2676_MSMEG2676_dna
GTTCCTCGGGATGACGTTCGCGAGCTTGGAGTTGTTCGCGACCATCGGCCCCGCGTTGGCGATCGCCATCGGGGTGGCGTTCCTGGCCGCGGTGACCTTGCTGCCCGCCATCATCGTGCTGGCCGGACGTCGTGGCTGGGTCTCACCACGACGCGAGATCACCGCGCGGTTCTGGCGCAGATCCGGCATTCGCATCGTGCGTCGTCCCGTGACCAACCTTGTCGCCAGTTTGATGGTGCTGCTCGTTCGTGATCCGCCCCGGCGTGTCTGGAGAGTTCTTCCGTTGGGAAGGATGGGCACGTGGGATCGAAGTCATCGAGGCGGTATCCAGACGAGCTGAAGGTGCGGGCGGTGCAGATGGTGGCCGATCTGCGCAGCGAGACAGTTTCGGAGTGGGAGGCGATGGGCCGGGTTGCTGACCTGCTGGGCGTCGGTACTGCCGAAACGGTGCGCAAATGGGTCCGCCAGGCTGAGATCGACGCCGGCTCTCGGGCGGGGCAGACCAGCGAGGAATCCGAGGTCCTGCGCAAGCTGCGCCGGGAGAATGCCGAACTCAAGCGGGCCAACGCGATCTTGAAGGCGGCCTCGGTTTTCTTCGCCGCCGAGCTCGACCGGCCCTCTCAGTAG

Protein Sequence 

>Ms2676_MSMEG2676_protein
VGSKSSRRYPDELKVRAVQMVADLRSETVSEWEAMGRVADLLGVGTAETVRKWVRQAEIDAGSRAGQTSEESEVLRKLRRENAELKRANAILKAASVFFAAELDRPSQ

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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