MSMEG2708 (MSMEG2708)

background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 hypE gmhA MSMEG2707 MSMEG2708 MSMEG2709 MSMEG2710 hypF
Species: M. smegmatis
Strain: MC2-155
PATRIC Annotation: -
Synonyms:
M. tuberculosis homologs
M. abscessus homologs
Gene Start: 2780312
Gene End: 2780503
Vulnerability Index (VI):
VI Lower Bound:
VI Upper Bound:
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [Gaia]

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]


DNA and Protein Sequence help

DNA Sequence

GAACTGCCGGATCCGGTGGGGCACGGTCGTCGAGGTCGAAGGCGAGCACGTGAAACTCGAATCCCGTCCCCTGGTTCGCAACGGCCGGCGCATCGAACTCGACAGCGCCGTAGCCGAATACGTCCGCTGGAGCCGCGGCGGCGCGTCGCTCATCGCGGCGCCCCGCCCCGGCGACACAGTCTCGGCACATTGGGACTGGGTGTGCGACACCCTGTCCCCCCACGACGTCACCGCGTTGACCGAATCGACCCTGACCACGCTCGGCGTCGTCAACGCGTTGCGCGAGGTGAAGGAGGAAGCATGACCACTCCGGGCGGACATCTGTCCGAGGAACCACAGGAAGAGCGCGGTGCGCCGGGTTCACGCGACGCCGGATCCGATGAGCCGTCGGGCGGCCCCACCGACCGGCCGTCGGGCACCTATCGGGGCGACGAGAGCGTGCCCGATCACGGTGCCGAAGGGGGCGCCGAAGGAGATGACCAGACCCCATGA

Protein Sequence

MTTPGGHLSEEPQEERGAPGSRDAGSDEPSGGPTDRPSGTYRGDESVPDHGAEGGAEGDDQTP 
Gene not present in the reference CRISPRi library.

Specific References

General References