MSMEG3433
ms3433
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 3502304 – 3503770
Vulnerability Index (VI):
M. tuberculosis homologs
M. abscessus homologs
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG3428 MSMEG3429 MSMEG3430 MSMEG3431 MSMEG3432 MSMEG3433 MSMEG3434 MSMEG3435 MSMEG3436
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms3433_MSMEG3433_dna
ATCGACCACCGACATGGGGCCGCGGCCCATCTTCGCCGTGCCGACCTGGTGCCAGAACGAACCACCTGCGTTGCGAAGGAATTCGTCGAGATCCCGGCCGGCGAGGTCACCGGGCATGACCGGGCGACGCACATAAGGCCGACCTGACTTGGCTCACGGTTTCCGGTTTGGGGTAGTGGCGGGTTCTTGACCTGCAGTTTCGGAGTCGGCTCGGCCGGAATTTGCGCACTAAGGTCGGGCCGTAGGCTGCCCTGGTGGCGTACGTGCGCACAGTGAAGACCGCTTCGGGGGCCACTGCGGTGCAGATCGTGTGGTCCACCCGACGCGGGTCACGCAACATCGAGCATGTGGGCTCGGCCCATGATGAGGCCGAGCTCGCAGCGCTCAAGGCCTCCGCTGCCGAGCGGTTGGCGGCCAACCAGGCGGTGCTGGATCTGGAGGTGTCCCCGCCGGCCGGTTCGGAGCCGTTGCCGATCACCTCCTCACAGATGACCCATCTGTGGGACGGGCTCTGTTCGGCGTATCGGATCCTCGGGTTCGACTCAGCCGCCGAGGGCGACAATGTGTTTCGGGATCTGGTGCTGGCCAGGATCATCGAACCCAGCAGCAAGGCCGACGCCGGACGGGTGCTCACCGAGGTCGGTGTCGAACCGGCCTCCTATGCCACGGTCAAACGCCGGCTGCCGATCTACGCCCAGCCGCAGTGGCGGCAGTCCTTGGCCGCGGCCAGTGCACGTCGCGCCGGGTTGGGGCCCGCATCGCTGGTGCTATTCGATGTGAGCACCTTGTATTTCGAGACCGACGCCGGCGACGGCTTCCGCGAGCCCGGATTCTCCAAGGAACGCCGACTCGAGCCGCAGATCACCCTGGGGTTGCTTACCGATGCCGCCGGGTTCCCGCTGACCGTGGAGGCCTTCGAGGGCAACCGCGCCGAGACCGCCACCATGCTGCCGGTGATCAACGCGTTCAAGGCCGCCCATCAACTCACCGATGTCACCGTGGTCGCCGATGCGGGCATGATCTCCGAGGCCAACCAGGTCGCGCTGCAGTCCGCCGGCCTGTCCTACATCCTCGGCGCCAAGATTCCGTTCCTGCCCGATGTGGTGCGCGAATGGCGGGACAAACACCCCGACGAGGCGATCCCCGATGGCCTGGTGCTCACCCAACCGTGGCCGGCCACCAGCAGCGAGAAGGCCCGCGGCATCCCGGACCGGGTCATCCACTACCAATTCCGCCACGACCGCGCCCGGCGCACCCTGCGCGGCATCGACGAGCAAGTGGCCAAGGCCCAGCGCGCAGTCGACGGGCACGCCCCGGTCAAGCGCAACCGCTACATCCAACTCACTGGCGCCACCAAGTCGGTGAACCGCACGCTGGAGGCCAAGACCCGCGCCCTGGCCGGCTGGAAGGGCTACACCACCAACCTCGTCGGGCAGCCCGCGTCGTTTGTCATCGATGCCTATCACCAGCTCTGGCACATCGAGAAGGCCTTCCGGATGTCCAAGCACGACCTGCAGGCCCGCCCGATCTACCACCATTTACGCGAATCGATCGAAGCCCACCTGAGCATCGTGGTCGCCGCAATGGCCGTCAGCCACTTCATCGAGACCCAAACCGGCTGGAGCATCAAGAAATTCGTCCGAACCGCACGCCGCTACCGCACCGTGAAGATCAAGGCCGGCACCCAGACCCTCACCGCCGCCGACCCGCTACCCGAGGACCTACGAGCAGTCCTCATCAAGATCCGCGCCGACGGTGCACACTAA

Protein Sequence 

>Ms3433_MSMEG3433_protein
VQIVWSTRRGSRNIEHVGSAHDEAELAALKASAAERLAANQAVLDLEVSPPAGSEPLPITSSQMTHLWDGLCSAYRILGFDSAAEGDNVFRDLVLARIIEPSSKADAGRVLTEVGVEPASYATVKRRLPIYAQPQWRQSLAAASARRAGLGPASLVLFDVSTLYFETDAGDGFREPGFSKERRLEPQITLGLLTDAAGFPLTVEAFEGNRAETATMLPVINAFKAAHQLTDVTVVADAGMISEANQVALQSAGLSYILGAKIPFLPDVVREWRDKHPDEAIPDGLVLTQPWPATSSEKARGIPDRVIHYQFRHDRARRTLRGIDEQVAKAQRAVDGHAPVKRNRYIQLTGATKSVNRTLEAKTRALAGWKGYTTNLVGQPASFVIDAYHQLWHIEKAFRMSKHDLQARPIYHHLRESIEAHLSIVVAAMAVSHFIETQTGWSIKKFVRTARRYRTVKIKAGTQTLTAADPLPEDLRAVLIKIRADGAH

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Growth Advantage in vitro TnSeq [Dragset et al. (2019)]

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