MSMEG3984
ms3984
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 4053599 – 4054810
Vulnerability Index (VI):
M. tuberculosis homologs Rv2013, Rv2014
M. abscessus homologs
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG3981 MSMEG3982 MSMEG3984 MSMEG3985 MSMEG3986
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms3984_MSMEG3984_dna
ACAAGGCAAGGGCACCGTGGAAATCTTTTGTAGCCACCTAATGGGTGTTGATCGGCGTGCCTCGAACGGATAACCGTCCAGCGCGGGGACGCTGATCACCGAGCCGCTGGCCGGTGAGCACTCCTGCCGCCTGGAACGATGGTCGATTTCTAGGGTTAGATCGTGCCCCGGCCGGTTGGTGAGGTCATCTACAGCGCTCATGGGATGTCGTGCCGGTTCGAGCACTGATCCATTAGGTCGCCGCCAGATGTCCTTCGGCTCGAACGGTTTCATCCACATCGAGCCAAGGAGGCGATGCGATGCTCTTCGTCGGAGACGACTGGGCAGAAGACCACCACGACCTGTACCTGATGAACGAGGCCGGCGACAGGCTGGCCTCACGGCGGCTGCCCGAGGGGCTGGCCGGAATTCGACTACTGCACGATCTCATCGCGGCCCACGCCGATGACCCCGCTCAGGTCGCCGTCGGAATCGAAACCGACCGCGGACTGTGGGTGGAGGCACTGACCGGCGCCGGTTATCAGGTGTACGCGGTCAATCCGCTGGCTGTGGCCCGCTATCGCGACCGCCACGCGGTGTCGGGAGCCAAGTCCGATGCCGCCGACGCCAAGCTGTTGGCCGATCTAGTGCGCACCGACCGACACAACCACCGTCTGATCGCCGGCGACACACCCGACGCCGAAGCGGTCAAGGTCCTCGCGCGGGCGCATCAGAATCTGATCTGGACCCGCAACCGGCACACCAACGCACTGCGCTCGGCACTACGCGAGTACTACCCCGCGGCGCTGGAGGCCTTCGACGATCTGTCCGACCGCGACGCGTTGGCGATCCTCGGACATGCACCCGACCCCCGACAAGCATCCAGCCTGAGCCTGGCCAAGATCCGCTCCGCACTCAAAGCTGCTGGGCGCCAACGCAACATCGACATCCGAGCCCAGGAGATCCAGGCCGCACTACGATCCGAACAACTCGCAGCACCGGCTGCGGTCACCGCGGCGTTCGCAGCGACAACGCGGGCCACCGTCGGGCTCGTCGTCGAGTTGAGTCGTCAGATCGACGACCTGGAGAACGAACTGGCCGCGCATTTTGAGACGCACCCGGACGCCGACATCTACCGCTCCCTGCCAGGACTTGGTGTCATCCTCGGCGCCCGGGTGCTCGGTGAGTTCGGGGACGACCCGAACCGATACACCAACGCCCAGTGTCGCAAAAACTACGCCGGAACCTCGCCATTGACCATTGCGTCCGGCAGGAAGCGCGCCGTACTGGCCCGCCACATCCGCAACCGTCGGCTCTACGACGCGATCGACCAGTGGGCCTTCTGCGCGCTAACCCGAAGTCCCGGAGCTCGACAGTTCTACGACCATCGCCGCGCTGAAGGCGACCTCCATCACCAAGCACTGCGGGCTCTGGGCAACCGCCTCGTCGGCATCCTGCACGGTTGCCTACGCCACCGGACCCGCTACGACGAACACAAAGCCTGGGCACACCGCACACCTGCCGCCGCTTGA

Protein Sequence 

>Ms3984_MSMEG3984_protein
MLFVGDDWAEDHHDLYLMNEAGDRLASRRLPEGLAGIRLLHDLIAAHADDPAQVAVGIETDRGLWVEALTGAGYQVYAVNPLAVARYRDRHAVSGAKSDAADAKLLADLVRTDRHNHRLIAGDTPDAEAVKVLARAHQNLIWTRNRHTNALRSALREYYPAALEAFDDLSDRDALAILGHAPDPRQASSLSLAKIRSALKAAGRQRNIDIRAQEIQAALRSEQLAAPAAVTAAFAATTRATVGLVVELSRQIDDLENELAAHFETHPDADIYRSLPGLGVILGARVLGEFGDDPNRYTNAQCRKNYAGTSPLTIASGRKRAVLARHIRNRRLYDAIDQWAFCALTRSPGARQFYDHRRAEGDLHHQALRALGNRLVGILHGCLRHRTRYDEHKAWAHRTPAAA

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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