MSMEG4133
ms4133
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 4212793 – 4213806
Vulnerability Index (VI):
M. tuberculosis homologs Rv3430c
M. abscessus homologs
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon TSS Legend ? Ju, 2024 (5) Li, 2017 (4) (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 29326668 (5) PMID: 38418874 MSMEG4128 MSMEG4129 MSMEG4130 MSMEG4131 MSMEG4132 MSMEG4133 MSMEG4134 MSMEG4135 MSMEG4136 MSMEG4137
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms4133_MSMEG4133_dna
GCCTGTACGACCAACGATGGTGGGGCGTACCTGCGCGTTGAGGGGTTGTATTCCTCGCAGATCGCCGAGTGGCGCAAACAACGCGATGCTGGGGTGTTGGAAGGCAAGGCACCTGGGGAGAAGGTCGGTAAACTCACCCGCGAGCAGGCCGAGATCGCCCGCCTGAAAAAGGAACTCGCCCAGGCCAATAATCGGCTGGCGACCACCGAGGCTGCCCTGGGGATCATGGGAAAAGCACACGCGCTCTTGGAGTCTCTCTCCGAGAGCGCGGACACCGACACGCCGCCGACCAAGCGCTGATGGATGCCTACAACGATCTGCGGGATATCCAGATTCCGACCCGCAAGGCCGCGGAGGTGACCGGCATGCACCGCTCGACGGCCACTCGACGCGCCAAACCCGCGCCGGCGCCTGCCGATCGGGCACCACGACCGGTCCCGGTCAACAAGCTCACCGAGTCCGAATGCACCCGGGTGGTTGAGGTGCTCAACAGTGCCCGGTTCGTCGATGCCGCGCCGATGCAGGTGTGGGCCACGTTGCTCGATGAAGGCAGCTACCTGTGTTCGGTGTCGACGATGTACCGCGTCCTCAATGCCAACAAGCTGGTCAAGGAGCGCCGTCGGCTGGCCCGGCACCGCAAAGCGGTCTGCCCGGAACTGGTGGCCACCGCGCCGCGGCAGGTGTATTCGTGGGACATCACCAAACTGGCCGGCCCGGTCAAAGGGGTCTACTACGACGCCTACGTGATGATCGACATTCACTCGCGTTACATCGTCGGGGTCCATGTGCACGCCCGCGAATGCGGCCAGCTGGCCAAGGAGATGATGGAACAGATCTTCGGCACCTACGGCATCCCACACGTCGTGCACGCTGATCGGGGCACCTCGATGACCAGCAACACCGTCGCCGGACTGCTCTCGGATCTGGGCGTCATCCGCTCGCATTCGCGGCCCAAGGTATCCAACGACAACCCCTACAGCGAGTCCTGGTTCAAGACCTTGAAGTATGCGCCGGCGTTCCCGGAACGCTTCGAATCCATCCATCACGCGAGGGATTTCATGGACCGATTCGTGCAGTGGTACAACCATGAACACCGCCACAGCGGCATCGGGCTGCACACACCCGCCGATGTGTTCTACGGCCTCGCCGGCGGGAAAGACACCCAGCGCCGAGCCGTGCTCGCCGACGCCAGGGCGCGCCACCCACGCCGATTCGGCCGCGACACCGCACCCAAGGTCATCGACCTACCTGAATCCGCGGCGATCAACCCACCCAAACCGGCCGAACAGGAGACCGAAACGGAAGCCGCTTAA

Protein Sequence 

>Ms4133_MSMEG4133_protein
MDAYNDLRDIQIPTRKAAEVTGMHRSTATRRAKPAPAPADRAPRPVPVNKLTESECTRVVEVLNSARFVDAAPMQVWATLLDEGSYLCSVSTMYRVLNANKLVKERRRLARHRKAVCPELVATAPRQVYSWDITKLAGPVKGVYYDAYVMIDIHSRYIVGVHVHARECGQLAKEMMEQIFGTYGIPHVVHADRGTSMTSNTVAGLLSDLGVIRSHSRPKVSNDNPYSESWFKTLKYAPAFPERFESIHHARDFMDRFVQWYNHEHRHSGIGLHTPADVFYGLAGGKDTQRRAVLADARARHPRRFGRDTAPKVIDLPESAAINPPKPAEQETETEAA

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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