MSMEG4223
ms4223
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 4303589 – 4303702
Vulnerability Index (VI):
M. tuberculosis homologs
M. abscessus homologs
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG4217 MSMEG4218 MSMEG4219 MSMEG4220 MSMEG4221 ftsZ MSMEG4223 MSMEG4224 MSMEG4225 murC
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms4223_MSMEG4223_dna
CACACGACCGGCGTGCGCGGCCGCGACCACACCCGCGCGGGCGTCGGCCATTAACACCGGAACACAATCGGCGGTAACCACCGCCAAAGCCAAACCGGGAACCGTGGTCACCAATGCGTCGGTGTCATTTACCGCACGTTCACGTGGACCGTCCACGGTGACAACACGATCACCGTGGACCTGATTCATCCACACGATTGCGTCGGCGCTCACCGCGTCCGCGAGGCGTTGACGATTGGCGGCCACCGCGGCCGGATCGTCACCCACGTGATCGCCGAGGTTGAACGAATCGTAGGGCGGTGCCGAAACACCACCGGCGCGGGTCGTCGTCACGCGCCGAATACGAACACTCACGGTTTCAGTATCCGGACCATTCGAACGCGGTGGCCGGCCGTCGGCTCAGTGCCGCATGA

Protein Sequence 

>Ms4223_MSMEG4223_protein
VPKHHRRGSSSRAEYEHSRFQYPDHSNAVAGRRLSAA

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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