MSMEG4522
ms4522
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 4610407 – 4611492
Vulnerability Index (VI):
M. tuberculosis homologs
M. abscessus homologs
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon TSS Legend ? Ju, 2024 (4) Li, 2017 (5) (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 38418874 (5) PMID: 29326668 MSMEG4519 MSMEG4520 MSMEG4521 MSMEG4522 MSMEG4523 MSMEG4524 MSMEG4525 MSMEG4526 MSMEG4527
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms4522_MSMEG4522_dna
CCCAAGGCCGAGAGCATGGACGCGATCCTGCGTCTCGACGAGGCGCCGCGCGGGCTGTACTCGGGTGCGGTGGTGACGTTCTCGGCCGACGGCGCGATGGACGCCGCGCTGACGTTGCGATCGGCCTACGAGGCGCACGGCGCGACGTGGCTGCGCGCCGGGGCGGGCATCATCGCCGAGTCGACCCCCGAGCGTGAGTTCGAGGAGACCTGCGAGAAACTCACCACCCTTGCGCCGCACCTGGTGCCGCGGGTCTAGTGTCCTGAGTCATTAATTGCGGCCTAGTTGTTAAACTAGGTCGTGCCGACTCCTCATGCCGCTGAGATTGTGTTGTCCGCTGATGAGCGGGCCGAGTTGGAGGGCTGGGCGCGGCGACGTACGAGTGCTGCCGGCCTGGCCATGCGGGCTCGAATTGTGTTGGCAGCTGCCGATGGTGGGTCCAATACTGAACTGGCCGATCGCCTGGAGTTGTCGATCGGCACGGTGCGGCGCTGGCGCAATCGGTTCGCTGAGCTGCGACTGGACGGCCTCGTTGATGAACCACGTCCGGGTCGGCCGCGGGTTGTCGGTGACGAGCAGATCGAAGCGTTGATCACCGCGACGTTGGAGACCACCCCGCCTGATGCCACCCATTGGTCAACCCGCTCGATGGCTGCCCATCTGGGGTTGAGTCAGTCGATGGTCTCGCGCGTCTGGCGAGCGTTCGGACTGGCTCCCCACAAGCAGGACTCGTGGAAACTGTCGAAAGACCCGCTGTTTGTGGCCAAGGTCCGCGATGTCGTCGGGCTGTACCTGAACCCACCGGAACGGGCCTTGGTGCTGTGCGTGGACGAGAAAACCCAGATCCAGGCACTGAACCGGACCCAACCGGTGTTCCCGATGTTGCCCGGCACCCCGGCGCGGGCCAGCCATGACTACGTTCGCCACGGCACCTCCAGCCTCTACGCCGCTCTCGACCTGACCACCGGCAAGGTGATCGGCGCCCTGCACTCTCGCCACCGAGCCACGGAGTTTCTGGCTTTTCTCAAGAAGATCGACGTCGAGGTCCCCGACGATCTTGATGTGCACTTGGTTCTCGACAACGCCTCCACGCACAAGACCCCTGCGGTAAAACGTTGGCTGACAGGCCATCCCAGATTTGTCCTGCACTTCACCCCGACCAGCTCGTCCTGGCTCAATCTCGTGGAACGCTGGTTCGCCGAGCTGACCACCAAGAAGCTGCGACGCTCCACCCACACCTCAGTTCGGCAACTCAACGCCGACATCCGAGCGTGGATCGACACCTGGAACGACAACCCCAAGCCCTACGTCTGGACCAAGACCGCCGATCAAATCCTGGCCAGCATCGCCAACTACTGCGCCCGAATTAATGACTCAGGACACTAG

Protein Sequence 

>Ms4522_MSMEG4522_protein
VPTPHAAEIVLSADERAELEGWARRRTSAAGLAMRARIVLAAADGGSNTELADRLELSIGTVRRWRNRFAELRLDGLVDEPRPGRPRVVGDEQIEALITATLETTPPDATHWSTRSMAAHLGLSQSMVSRVWRAFGLAPHKQDSWKLSKDPLFVAKVRDVVGLYLNPPERALVLCVDEKTQIQALNRTQPVFPMLPGTPARASHDYVRHGTSSLYAALDLTTGKVIGALHSRHRATEFLAFLKKIDVEVPDDLDVHLVLDNASTHKTPAVKRWLTGHPRFVLHFTPTSSSWLNLVERWFAELTTKKLRRSTHTSVRQLNADIRAWIDTWNDNPKPYVWTKTADQILASIANYCARINDSGH

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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