MSMEG4550
ms4550
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 4641611 – 4642816
Vulnerability Index (VI):
M. tuberculosis homologs Rv2014, Rv2177c
M. abscessus homologs
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon TSS Legend ? Ju, 2024 (4) Li, 2017 (5) (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 38418874 (5) PMID: 29326668 MSMEG4547 MSMEG4548 MSMEG4549 MSMEG4550 MSMEG4551 ssuD MSMEG4553
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms4550_MSMEG4550_dna
CTCGTCCCCCGACCGGCGCAGTCGGATCATCTGTGGTGGTCACGGTGGTGTCCTTAAGTTCGTAGTTGCAGTTTCTTCGTGTTGTTGAGGCAGTTACGTTGGGCTGTGACCCGGGTGGGTCGGGTGTGGCTGTGGTGTGTGTTGCCGGCCCCTTGGTGCGGCTTGAAAGGACTGGCCGCCCGGCCTGCCTGGACTTCTCTGGCCGCTGATTGAGATCTGCGATGTGATCGCTTGTTTAAGGAAATGCTGGCGGGGTTGTCCTTGGGGATCATGTTGGCAGACAAGCGAAAAGAGGTGTGATGGCGGCGGGCCAGGTGTGGGCTGGAGTGGATGTCGGTAAAGAGCATCACTGGGTATGTGTGGTCGACGACAGCGGGAAGGTGGTGTTGTCGCGCCGGTTGGTTAACGATGAGCAACCGATCCGAGAGCTCGTGGCTGAAATCGACGAGCTGGCCGAGCGAGTGTTGTGGGCGGTGGACCTGACCACGGTGTATGCCGCCCTGTTGTTGACGGTGCTGGCCGACGCTGGCAAAACGGTCCGGTACCTGGCCGGCCGGGCGGTGTGGCAGGCCTCGGCGACCTACCGCGGTGGGGAGGCCAAAACCGACGCCAAAGATGCACGGGTGATCGCCGACCAGTCGCGGATGCGCGGGCAGGACTTGCCCGTTCTGCATCCCAATGATGACTTGATCAGCGAGTTGCGGATGCTCACCGGCCATCGCGCCGACCTCGTGGCCGACCGCACCCGCACAATAAACCGGCTGCGCCAACAACTCGTCGCGGTCTGCCCGGCCCTGGAACGAGCCGCCCAACTGAGCCAAGACCGTGGCTGGGTGGTATTGCTGGCGCGCTACCAGCGTCCCAAAGCGATTCGGCAAAGCGGTGTTTCGCGGCTGACCAAAGTCTTGACCGATGCCGGTGTGCGCAACGCCGCCTCGATCGCGGGGGCTGCGGTGGCCGCGGTGAAAACCCAGACGGTGCGTCTGCCCGGCGAAGAGGTGGCCGCCGGGTTGGTCGCTGATCTGGCACGGGAGGTGATTGCCCTCGATGACCGCATCAAGACCACCGACGCCGACATCGAGGGCCGATTTCGCCGCCATCCACTCGCCGAGGTGATCACCAGTATGCCCGGCATGGGATTTCGACTCGGCGCCGAACTCCTCGCTGCCGTCGGTGATCCCGCACTGATCGGATCGGCTGACCAACTCGCGGCCTGGGCCGGCCTGGCACCAGTGTCTCGAGACTCCAGAAAGCGCACCGGACGACTGCACACCCCCAAGCGCTACAGTCGCCGACTGCGCCGAGTCATGTACATGTCGGCGTTGACCGCGATCCGCTGCGACCCAGATTCCAAGGCCTACTACCAGCGCAAACGAGACGAAGGAAAGCGGCCGATCCCCGCCACCATCTGCCTGGCACGACGGCGCACCAACGTTCTCTACGCCCTCATCCGCGACAACCGGACCTGGCAACCTGAATCACCCCCAAACATCGCGGCGGCTTGA

Protein Sequence 

>Ms4550_MSMEG4550_protein
MAAGQVWAGVDVGKEHHWVCVVDDSGKVVLSRRLVNDEQPIRELVAEIDELAERVLWAVDLTTVYAALLLTVLADAGKTVRYLAGRAVWQASATYRGGEAKTDAKDARVIADQSRMRGQDLPVLHPNDDLISELRMLTGHRADLVADRTRTINRLRQQLVAVCPALERAAQLSQDRGWVVLLARYQRPKAIRQSGVSRLTKVLTDAGVRNAASIAGAAVAAVKTQTVRLPGEEVAAGLVADLAREVIALDDRIKTTDADIEGRFRRHPLAEVITSMPGMGFRLGAELLAAVGDPALIGSADQLAAWAGLAPVSRDSRKRTGRLHTPKRYSRRLRRVMYMSALTAIRCDPDSKAYYQRKRDEGKRPIPATICLARRRTNVLYALIRDNRTWQPESPPNIAAA

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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