MSMEG4927
ms4927
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 5022827 – 5023528
Vulnerability Index (VI):
M. tuberculosis homologs
M. abscessus homologs
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG4925 MSMEG4926 MSMEG4927 MSMEG4928 rrfB rrlB
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms4927_MSMEG4927_dna
GTGCGCTCGCCGGCGAAGTACTCGGCCAGCTGTTCGACAACTTCAGGAAATGCGCTGTCATCGACCTCCCAACCGTCACGGCTGGGCTCATAGGTCTGGTCCTCCATACGAAGGTGCACCAGGTGTCCGTCGCGGCCCGCGAGGGTCAACGGACCGACCGGGCTGTCGACTGTGCGGCATTTCAGGGCTCTTCGCACTTGACGGTGTAGAGACGATCAGCTGCTTTCGCGCTGTGATCGAGGGGTCTGGTTGGCTTGGGGTGTGCCGGAGAAGAAGCGGAAGAGCAAGAGGAAGAGCGGAGTGTCCGGGGGCAGTGTGGACCTGGCGTTGCTGCAGAAGCTAATGGCCGACGCTGGTCGGAACGTGTTCGCGGGAATGTTCGATGAGCCGACGCCCGAGGTGCGGGCGGTGCCGGATCGTGCGCGGGGCTTCCGGGTGCGCGTCGACCTGATGTACGCCAAGCCGCCGATCTGGCGTCGGCTGGACCTGCCGGGCGACCTCATGCTCGATGAGCTCCATGTTGTGCTGCAGGTCGTTATGGGCTGGCAGGACAGTCATCTGCATAAGTTCGGTGTCGGGGCGGACCGGCGGACCCGTGCCTACTTCGTCACCGGGTTTGATCTCAGCGAAGGCGACGACGGTGTCGTCGAGGACAGCGTGCGCCTCGATCAGGTGGTGTCCGATAAGGGCGAGCGGTTGTTCTACGATTACGACTTCGGCGACGGATGGGACCACGTGCTCGTGGTCGAAGACGTTTTCGATGATCCGCCCCCGGCTGCGGTGTGTCTGACGGGAAAGATGGCCTGTCCGCCGGAGGACTGTGGTGGCCTGGGCGGCTATGAGGAGTTGGCTGCGTGGGTTCGCGGCGGGTACGACCCGCGGGAAACGCCGATGGGACTCGGTGCGCAGGAGATGAGGGACTGGCTGCCCCGGGGCTGGCACCCCGACCGTTTCTCGGTGGCCGAGACCAATGACGCTCTGGCCGCGTTGAACACGCGTTGA

Protein Sequence 

>Ms4927_MSMEG4927_protein
VSGGSVDLALLQKLMADAGRNVFAGMFDEPTPEVRAVPDRARGFRVRVDLMYAKPPIWRRLDLPGDLMLDELHVVLQVVMGWQDSHLHKFGVGADRRTRAYFVTGFDLSEGDDGVVEDSVRLDQVVSDKGERLFYDYDFGDGWDHVLVVEDVFDDPPPAAVCLTGKMACPPEDCGGLGGYEELAAWVRGGYDPRETPMGLGAQEMRDWLPRGWHPDRFSVAETNDALAALNTR

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Growth Advantage in vitro TnSeq [Dragset et al. (2019)]

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