rrlB
ms4930
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 5024461 – 5027580
Vulnerability Index (VI):
M. tuberculosis homologs
M. abscessus homologs
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG4926 MSMEG4927 MSMEG4928 rrfB rrlB rrsB murA
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms4930_rrlB_dna
TGGCGCCGGCTTGGTGCACAGCAAACGTTGAGATGCGGTGTGGGAAACGCTGTTTCGATGGACTGCCAGACACACTATTGGGCCCTGAGACAACAGGCCCGTTGTTCCCTGGCCACTGTGTGTGGTGGGAGGCGTGTTGTTGCCCTGCTTTGGTGGTGGGGTGTGGTGTTTGATTTGTGGATAGTGGTTGCGAGCATCTAGTTCGTAAGAGTGTGGCTGCCGGCCTTTGAGGTTGGGTGGCGCATTGTTGCGGACAAATTGATGTGCAATTTTTCTTCTGATTATTGGTTTTTTGTGTTGTAAGTGTTTAAGGGCGCATGGTGGATGCCTTGGCACTGGGAGCCGATGAAGGACGTAGGAGGCTGCGATAAGCCTCGGGGAGCTGTCAACCGAGCGTTGATCCGAGGATGTCCGAATGGGGAAACCCGGCACGAGTGATGTCGTGTCACCAGGCGCTGAATATATAGGCGTCTGGGGGGAACGCGGGGAAGTGAAACATCTCAGTACCCGTAGGAAGAGAAAACAAAATGTGATTCCGTGAGTAGTGGCGAGCGAAAGCGGAGGATGGCTAAACCGTATGCATGTGATACCGGGTAGGGGTTGTGTGTGCGGGGTTGTGGGACCTATCTTTCCGGCTCTACCTGGCTGGAGGGCAGTGAGAAAATGTTGTGGTTAGCGGAAATGGCTTGGGATGGCCTGCCGTAGACGGTGAGAGCCCGGTACGTGAAAACCCGACGTCTGTCTTGATGGTGTTCCCGAGTAGCAGCGGGCCCGTGGAATCTGCTGTGAATCTGCCGGGACCACCCGGTAAGCCTGAATACTTCCCAGTGACCGATAGCGGATTAGTACCGTGAGGGAATGGTGAAAAGTACCCCGGGAGGGGAGTGAAAGAGTACCTGAAACCGTGCGCTTACAATCCGTCAGAGCCCTCGACGTGTCGTGGGGTGATGGCGTGCCTTTTGAAGAATGAGCCTGCGAGTCAGGGACATGTCGCGAGGTTAACCCGGGTGGGGTAGCCGCAGCGAAAGCGAGTCTGAATAGGGCGTATCCACACAAGAGTGTGTGGTGTAGTGGTGTGTTCTGGACCCGAAGCGGAGTGATCTACCCATGGCCAGGGTGAAGCGCGGGTAAGACCGCGTGGAGGCCCGAACCCACTTAGGTTGAAGACTGAGGGGATGAGCTGTGGGTAGGGGTGAAAGGCCAATCAAACTCCGTGATAGCTGGTTCTCCCCGAAATGCATTTAGGTGCAGCGTCGCATGTTTCTTGCCGGAGGTAGAGCTACTGGATGGCCGATGGGCCCCACAGGGTTACTGACGTCAGCCAAACTCCGAATGCCGGTAAGTCCAAGAGTGCGGCAGTGAGACGGCGGGGGATAAGCTCCGTGCGTCGAGAGGGAAACAGCCCAGATCGCCGGCTAAGGCCCCTAAGCGTGTGCTAAGTGGAAAAGGATGTGCAGTCGCGAAGACAACCAGGAGGTTGGCTTAGAAGCAGCCACCCTTGAAAGAGTGCGTAATAGCTCACTGGTCAAGTGATTGTGCGCCGATAATGTAGCGGGGCTCAAGCACACCGCCGAAGCCGCGGCAGCCAACGTGTTGGCTGGGTAGGGGAGCGTCCTGCATCCGGTGAAGCCGCCGAGTGATCGAGTGGTGGAGGGTGTGGGAGTGAGAATGCAGGCATGAGTAGCGATTAGGCAAGTGAGAACCTTGCCCGCCGAAAGACCAAGGGTTCCTGGGCCAGGCCAGTCCGCCCAGGGTGAGTCGGGACCTAAGGCGAGGCCGACAGGCGTAGTCGATGGACAACGGGTTGATATTCCCGTACCCGTGTATGTGCGTCCATGATGAATCAGCGGTACTAACCATCCAAAACCACCGTGACCGCACCTTTCGGGGTGTGGCGTTGGTGGGGCTGCATGGGACCTTCGTTGGTAGTAGTCAAGCGATGGGGTGACGCAGGAAGGTAGCCGTACCGGTCAGTGGTAATACCGGGGTAAGCCTGTAGGGAGTCAGATAGGTAAATCCGTCTGGCATATATCCTGAGAGGTGATGCATAGCCGAGTGAGGCGAATTCGGTGATCCTATGCTGCCGAGAAAAGCCTCTAGCGAGGACATACACGGCCCGTACCCCAAACCAACACAGGTGGTCAGGTAGAGAATACTAAGGCGTACGAGTGAACTATGGTTAAGGAACTCGGCAAAATGCCCCCGTAACTTCGGGAGAAGGGGGACCCACATGGCGTGTAAGCCTTTACGGCCCAAGCGTGAGTGGGTGGCACAAACCAGTGAGAAGCGACTGTTTACTAAAAACACAGGTCCGTGCGAAGTCGCAAGACGATGTATACGGACTGACGCCTGCCCGGTGCTGGAAGGTTAAGAGGACCCGTTAACTCCCTTTGGGGGTGAAGCGGAGAATTTAAGCCCCAGTAAACGGCGGTGGTAACTATAACCATCCTAAGGTAGCGAAATTCCTTGTCGGGTAAGTTCCGACCTGCACGAATGGCGTAACGACTTCTCAACTGTCTCAACCATAGACTCGGCGAAATTGCACTACGAGTAAAGATGCTCGTTACGCGCGGCAGGACGAAAAGACCCCGGGACCTTCACTACAACTTGGTATTGGTGCTCGATACGGTTTGTGTAGGATAGGTGGGAGACTGTGAAGCTCACACGCCAGTGTGGGTGGAGTCGTTGTTGAAATACCACTCTGATCGTATTGGGCCTCTAACCTCGGACCGTATATCCGGTTCAGGGACAGTGCCTGGTGGGTAGTTTAACTGGGGCGGTTGCCTCCTAAAATGTAACGGAGGCGCCCAAAGGTTCCCTCAACCTGGACGGCAATCAGGTGTTGAGTGTAAGTGCACAAGGGAGCTTGACTGCGAGACGGACATGTCGAGCAGGGACGAAAGTCGGGACTAGTGATCCGGCACCTCTGAGTGGAAGGGGTGTCGCTCAACGGATAAAAGGTACCCCGGGGATAACAGGCTGATCTTCCCCAAGAGTCCATATCGACGGGATGGTTTGGCACCTCGATGTCGGCTCGTCGCATCCTGGGGCTGGAGCAGGTCCCAAGGGTTGGGCTGTTCGCCCATTAAAGCGGCACGCGAGCTGGGTTTAGAACGTCGTGAGACAGTTCGGTCTCTATCCGCCGCGCGCGTCAGAAGCTTGAGGAAACCTGTCCCTAGTACGAGAGGACCGGGACGGACGAACCTCTGGTATACCAGTTGTCCCACCAGGGGCACGGCTGGATAGCCACGTTCGGACAGGATAACCGCTGAAAGCATCTAAGCGGGAAACCTCTTCCAAGACCAGGCTTCTCACCCTCTAGGAGGGATAAGGCCCCCCGCAGACCACGGGATTGATAGACCAGACCTGGAAGCCTAGTAATAGGTGCAGGGAACTGGCACTAACCGGCCGAAAACTTAC

Protein Sequence 

>Ms4930_RrlB_protein
VFKGAWWMPWHWEPMKDVGGCDKPRGAVNRALIRGCPNGETRHE_CRVTRR_IYRRLGGTRGSETSQYP_EEKTKCDSVSSGERKRRMAKPYACDTG_GLCVRGCGTYLSGSTWLEGSEKMLWLAEMAWDGLP_TVRARYVKTRRLS_WCSRVAAGPWNLL_ICRDHPVSLNTSQ_PIAD_YREGMVKSTPGGE_KST_NRALTIRQSPRRVVG_WRAF_RMSLRVRDMSRG_PGWGSRSESESE_GVSTQECVV_WCVLDPKRSDLPMARVKRG_DRVEARTHLG_RLRG_AVGRGERPIKLRDSWFSPKCI_VQRRMFLAGGRATGWPMGPTGLLTSAKLRMPVSPRVRQ_DGGG_APCVERETAQIAG_GP_ACAKWKRMCSREDNQEVGLEAATLERVRNSSLVK_LCADNVAGLKHTAEAAAANVLAG_GSVLHPVKPPSDRVVEGVGVRMQA_VAIRQVRTLPAERPRVPGPGQSAQGESGPKARPTGVVDGQRVDIPVPVYVRP__ISGTNHPKPP_PHLSGCGVGGAAWDLRW__SSDGVTQEGSRTGQW_YRGKPVGSQIGKSVWHIS_EVMHSRVRRIR_SYAAEKSL_RGHTRPVPQTNTGGQVENTKAYE_TMVKELGKMPP_LREKGDPHGV_AFTAQA_VGGTNQ_EATVY_KHRSVRSRKTMYTD_RLPGAGRLRGPVNSLWG_SGEFKPQ_TAVVTITILR_RNSLSGKFRPARMA_RLLNCLNHRLGEIALRVKMLVTRGRTKRPRDLHYNLVLVLDTVCVG_VGDCEAHTPVWVESLLKYHSDRIGPLTSDRISGSGTVPGG_FNWGGCLLKCNGGAQRFPQPGRQSGVECKCTRELDCETDMSSRDESRD__SGTSEWKGCRSTDKRYPGDNRLIFPKSPYRRDGLAPRCRLVASWGWSRSQGLGCSPIKAARELGLERRETVRSLSAARVRSLRKPVPSTRGPGRTNLWYTSCPTRGTAG_PRSDRITAESI_AGNLFQDQASHPLGGIRPPADHGIDRPDLEA___VQGTGTNRPKTY

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Unknown in vitro TnSeq [Dragset et al. (2019)]

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